- Signal peptide of FadA adhesin from Fusobacterium nucleatum plays a novel structural role by modulating the filament's length and width
[作者:Temoin, S; Wu, KL; Wu, V; Shoham, M; Han, YPW,期刊:FEBS Letters, 页码:1-6 , 文章类型: Article,,卷期:2012年586-1]
- FadA, a novel adhesin of periodontal pathogen Fusobacterium nucleatum is composed of two forms, pre-FadA and mature FadA (mFadA), constituting the functional FadA complex (FadAc). By electron microscopy, we observed that...
- Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR (vol 585, pg 3582, 2011)
[作者:Huang, TC; Chang, HY; Chen, CY; Wu, PY; Lee, H; Liao, YF; Hsu, WM; Huang, HC; Juan, HF,期刊:FEBS Letters, 页码:107-107 , 文章类型: Correction,,卷期:2012年586-1]
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- Rpa43 and its partners in the yeast RNA polymerase I transcription complex (vol 585, pg 3355, 2011)
[作者:Beckouet, F; Mariotte-Labarre, S; Peyroche, G; Nogi, Y; Thuriaux, P,期刊:FEBS Letters, 页码:108-108 , 文章类型: Correction,,卷期:2012年586-1]
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- Muscle FBPase binds to cardiomyocyte mitochondria under glycogen synthase kinase-3 inhibition or elevation of cellular Ca(2+) level
[作者:Gizak, A; Pirog, M; Rakus, D,期刊:FEBS Letters, 页码:13-19 , 文章类型: Article,,卷期:2012年586-1]
- A growing body of research suggests that fructose 1,6-bisphosphatase (FBPase) might be involved in regulation of cell mortality/survival. However, the precise role of FBPase in the process remains unknown. Here, we show ...
- MicroRNA-451 regulates p38 MAPK signaling by targeting of Ywhaz and suppresses the mesangial hypertrophy in early diabetic nephropathy
[作者:Zhang, Z; Luo, XM; Ding, ST; Chen, JX; Chen, T; Chen, X; Zha, H; Yao, L; He, XY; Peng, HM,期刊:FEBS Letters, 页码:20-26 , 文章类型: Article,,卷期:2012年586-1]
- Diabetic nephropathy (DN) is a major diabetic complication. However, the initiating molecular events triggering DN are unknown. In this study we focused on microRNA-451 (miR-451), which is downregulated during early DN. ...
- Subsets of ATP-sensitive potassium channel (K(ATP)) inhibitors increase gap junctional intercellular communication in metastatic cancer cell lines independent of SUR expression
[作者:Bodenstine, TM; Vaidya, KS; Ismail, A; Beck, BH; Diers, AR; Edmonds, MD; Kirsammer, GT; Landar, A; Welch, DR,期刊:FEBS Letters, 页码:27-31 , 文章类型: Article,,卷期:2012年586-1]
- Gap junctional intercellular communication (GJIC) regulates cellular homeostasis by propagating signaling molecules, exchanging cellular metabolites, and coupling electrical signals. In cancer, cells exhibit altered rate...
- Tristetraprolin down-regulates IL-17 through mRNA destabilization
[作者:Lee, HH; Yoon, NA; Vo, MT; Kim, CW; Woo, JM; Cha, HJ; Cho, YW; Lee, BJ; Cho, WJ; Park, JW,期刊:FEBS Letters, 页码:41-46 , 文章类型: Article,,卷期:2012年586-1]
- An excess of interleukin 17 (IL-17) may contribute to chronic inflammatory disorders, but mechanisms that regulate IL-17 in immune cells are unclear. Here we report that tristetraprolin (TTP) inhibits IL-17 production in...
- Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles
[作者:Simon, D; Garcia-Garcia, E; Royo, F; Falcon-Perez, JM; Avila, J,期刊:FEBS Letters, 页码:47-54 , 文章类型: Article,,卷期:2012年586-1]
- Increasing amounts of tau protein were expressed in non-neuronal cells. When intracellular amounts reached a threshold level, tau protein was released to the extracellular culture medium in association with membrane vesi...
- The molecular basis for inhibition of sulindac and its metabolites towards human aldose reductase
[作者:Zheng, XH; Zhang, LP; Zhai, J; Chen, YY; Luo, HB; Hu, XP,期刊:FEBS Letters, 页码:55-59 , 文章类型: Article,,卷期:2012年586-1]
- Sulindac (SLD) exhibits both the highest inhibitory activity towards human aldose reductase (AR) among popular non-steroidal anti-inflammatory drugs and clear beneficial clinical effects on Type 2 diabetes. However, the ...
- Length-dependent compaction of intrinsically disordered proteins
[作者:Uversky, VN; Santambrogio, C; Brocca, S; Grandori, R,期刊:FEBS Letters, 页码:70-73 , 文章类型: Article,,卷期:2012年586-1]
- This work investigates the effect of chain length on the degree of compaction of intrinsically disordered proteins (IDPs). The three main IDP types, native coil (NC), pre-molten globule (PMG) and molten globule (MG), are...
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