- Maturation cleavage within the ectodomain of Lassa virus glycoprotein relies on stabilization by the cytoplasmic tail
[作者:Schlie, K; Strecker, T; Garten, W,期刊:FEBS Letters, 页码:4379-4382 , 文章类型: Article,,卷期:2010年584-21]
- The Lassa virus glycoprotein consists of an ectodomain, a transmembrane anchor, and a cytoplasmic domain. It is synthesized as an inactive precursor and cleaved within the ectodomain to yield the mature form. Here, we sh...
- Grb14 inhibits FGF receptor signaling through the regulation of PLC gamma recruitment and activation
[作者:Browaeys-Poly, E; Blanquart, C; Perdereau, D; Antoine, AF; Goenaga, D; Luzy, JP; Chen, HX; Garbay, C; Issad, T; Cailliau, K; Burnol, AF,期刊:FEBS Letters, 页码:4383-4388 , 文章类型: Article,,卷期:2010年584-21]
- To decipher the mechanism involved in Grb14 binding to the activated fibroblast growth factor receptor (FGFR), we used the bioluminescence resonance energy transfer (BRET) technique and the Xenopus oocyte model. We showe...
- Golgi-localized KIAA0725p regulates membrane trafficking from the Golgi apparatus to the plasma membrane in mammalian cells
[作者:Sato, S; Inoue, H; Kogure, T; Tagaya, M; Tani, K,期刊:FEBS Letters, 页码:4389-4395 , 文章类型: Article,,卷期:2010年584-21]
- Mammals have three members of the intracellular phospholipase A(1) protein family (phosphatidic acid preferring-phospholipase A(1), p125, and KIAA0725p). In this study, we showed that KIAA0725p is localized in the Golgi,...
- Regulation of splicing enhancer activities by RNA secondary structures
[作者:Liu, W; Zhou, Y; Hu, ZX; Sun, T; Denise, A; Fu, XD; Zhang, Y,期刊:FEBS Letters, 页码:4401-4407 , 文章类型: Article,,卷期:2010年584-21]
- In this report, we studied the effect of RNA structures on the activity of exonic splicing enhancers on the SMN1 minigene model by engineering known ESEs into different positions of stable hairpins. We found that as shor...
- Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor
[作者:Kovac, S; Xiao, L; Shulkes, A; Patel, O; Baldwin, GS,期刊:FEBS Letters, 页码:4413-4418 , 文章类型: Article,,卷期:2010年584-21]
- The involvement of the gastrointestinal hormone gastrin in the development of gastrointestinal cancer is highly controversial. Here we demonstrate a positive-feedback loop whereby gastrin, acting via the CCK2 receptor, i...
- A novel secreted metzincin metalloproteinase from Bacillus intermedius
[作者:Sabirova, AR; Rudakova, NL; Balaban, NP; Ilyinskaya, ON; Demidyuk, IV; Kostrov, SV; Rudenskaya, GN; Sharipova, MR,期刊:FEBS Letters, 页码:4419-4425 , 文章类型: Article,,卷期:2010年584-21]
- The mprBi gene from Bacillus intermedius 3-19 encoding a novel secreted metalloproteinase was identified. The mpriBi gene was expressed in an extracellular proteinase-deficient Bacillus subtilis BG 2036 strain and the co...
- The small RNA expression profile of the developing murine urinary and reproductive systems
[作者:Aguilar, ALG; Piskol, R; Beitzinger, M; Zhu, JY; Kruspe, D; Aszodi, A; Moser, M; Englert, C; Meister, G,期刊:FEBS Letters, 页码:4426-4434 , 文章类型: Article,,卷期:2010年584-21]
- microRNAs (miRNAs) are small non-coding RNAs with fundamental roles in the regulation of gene expression. miRNAs assemble with Argonaute (Ago) proteins to miRNA-protein complexes (miRNPs), which interact with distinct bi...
- Protein kinase C mu mediates adenosine-stimulated steroidogenesis in primary rat adrenal cells
[作者:Chen, YC; Chen, Y; Huang, SH; Wang, SM,期刊:FEBS Letters, 页码:4442-4448 , 文章类型: Article,,卷期:2010年584-21]
- Adenosine (Ado), an endogenous nucleoside, can stimulate corticosterone synthesis in adrenal cells via the A(2A)/A(2B) adenosine receptors (ARs). This study evaluated the contribution of protein kinase C (PKC) isoforms i...
- Studying base pair open-close kinetics of tRNA(Leu) by TROSY-based proton exchange NMR spectroscopy
[作者:Hao, ZX; Tan, M; Liu, CD; Feng, R; Wang, ED; Zhu, G,期刊:FEBS Letters, 页码:4449-4452 , 文章类型: Article,,卷期:2010年584-21]
- The millisecond conformational flexibility is functionally important for nucleic acids and can be studied through probing the base pair open-close kinetics by proton exchange nuclear magnetic resonance (NMR) spectroscopy...
- NMR study of hydrogen exchange during the B-Z transition of a DNA duplex induced by the Z alpha domains of yatapoxvirus E3L
[作者:Lee, EH; Seo, YJ; Ahn, HC; Kang, YM; Kim, HE; Lee, YM; Choi, BS; Lee, JH,期刊:FEBS Letters, 页码:4453-4457 , 文章类型: Article,,卷期:2010年584-21]
- The Yaba-like disease viruses (YLDV) are members of the Yatapoxvirus family and have double-stranded DNA genomes. The E3L protein, which is essential for pathogenesis in the vaccinia virus, consists of two domains: an N-...
- Delta 160p53 is a novel N-terminal p53 isoform encoded by Delta 133p53 transcript
[作者:Marcel, V; Perrier, S; Aoubala, M; Ageorges, S; Groves, MJ; Diot, A; Fernandes, K; Tauro, S; Bourdon, JC,期刊:FEBS Letters, 页码:4463-4468 , 文章类型: Article,,卷期:2010年584-21]
- p53 gene expresses several protein isoforms modulating p53-mediated responses through regulation of gene expression. Here, we identify a novel p53 isoform, Delta 160p53, lacking the first 159 residues. By knockdown exper...
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