- Beta-2 adrenergic receptor mediated ERK activation is regulated by interaction with MAGI-3
[作者：Yang, XM; Zheng, JF; Xiong, Y; Shen, H; Sun, LC; Huang, Y; Sun, CY; Li, Y; He, JQ,期刊：FEBS Letters, 页码：2207-2212 , 文章类型： Article，,卷期：2010年584-11]
- The beta-2 adrenergic receptor (beta 2AR) has a carboxyl terminus motif that can interact with PSD-95/discs-large/ZO1 homology (PDZ) domain-containing proteins. In this paper, we identified membrane-associated guanylate ...
- Hexokinase inhibits flux of fluorescently labeled ATP through mitochondrial outer membrane porin
[作者：Perevoshchikova, IV; Zorov, SD; Kotova, EA; Zorov, DB; Antonenko, YN,期刊：FEBS Letters, 页码：2397-2402 , 文章类型： Article，,卷期：2010年584-11]
- Mitochondrial function requires maintaining metabolite fluxes across the mitochondrial outer membrane, which is mediated primarily by the voltage dependent anion channel (VDAC). We applied fluorescence correlation spectr...
- Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice
[作者：Lipina, C; Kendall, H; McPherron, AC; Taylor, PM; Hundal, HS,期刊：FEBS Letters, 页码：2403-2408 , 文章类型： Article，,卷期：2010年584-11]
- Myostatin deficiency leads to both an increased rate of protein synthesis and skeletal muscle hypertrophy. However, the mechanisms involved in mediating these effects are not yet fully understood. Here, we demonstrate th...
- Evidence for leptin receptor isoforms heteromerization at the cell surface
[作者：Bacart, J; Leloire, A; Levoye, A; Froguel, P; Jockers, R; Couturier, C,期刊：FEBS Letters, 页码：2213-2217 , 文章类型： Article，,卷期：2010年584-11]
- Leptin mediates its metabolic effects through several leptin receptor (LEP-R) isoforms. In humans, long (LEPRb) and short (LEPRa,c,d) isoforms are generated by alternative splicing. Most of leptin's effects are believed ...
- Cellular factors implicated in prion replication
[作者：Abid, K; Morales, R; Soto, C,期刊：FEBS Letters, 页码：2409-2414 , 文章类型： Article，,卷期：2010年584-11]
- Prions are the unconventional infectious agents responsible for prion diseases, which are composed mainly by the misfolded prion protein (PrPSc) that replicates by converting the host associated cellular prion protein (P...
- Regulation of Trk-dependent potassium transport by the calcineurin pathway involves the Hal5 kinase
[作者：Casado, C; Yenush, L; Melero, C; Ruiz, MD; Serrano, R; Perez-Valle, J; Arino, J; Ramos, J,期刊：FEBS Letters, 页码：2415-2420 , 文章类型： Article，,卷期：2010年584-11]
- The phosphatase calcineurin and the kinases Hal4/Hal5 regulate high-affinity potassium uptake in Saccharomyces cerevisiae through the Trk1 transporter. We demonstrate that calcineurin is necessary for high-affinity potas...
- The steroid receptor RNA activator protein is recruited to promoter regions and acts as a transcriptional repressor
[作者：Chooniedass-Kothari, S; Hamedani, MK; Auge, C; Wang, XM; Carascossa, S; Yan, Y; Cooper, C; Vincett, D; Myal, Y; Jalaguier, S; Cavailles, V; Leygue, E,期刊：FEBS Letters, 页码：2218-2224 , 文章类型： Article，,卷期：2010年584-11]
- Products of the steroid receptor RNA activator (SRA1) gene have the unusual property to function both at the RNA and the protein levels. SRA-RNA has long been known to increase the activity of multiple nuclear receptors....
- Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter
[作者：Min, JY; Lim, SO; Jung, G,期刊：FEBS Letters, 页码：2427-2432 , 文章类型： Article，,卷期：2010年584-11]
- Catalase, which decomposes reactive oxygen species (ROS), is reduced in hepatocellular carcinoma (HCC); however, the reasons are poorly defined. In this study, it is demonstrated that prolonged exposure to ROS induced me...
- K+ transport characteristics of the plasma membrane tandem-pore channel TPK4 and pore chimeras with its vacuolar homologs
[作者：Marcel, D; Muller, T; Hedrich, R; Geiger, D,期刊：FEBS Letters, 页码：2433-2439 , 文章类型： Article，,卷期：2010年584-11]
- Vacuolar tandem-pore channels could not be analysed in Xenopus oocytes so far, due to misguided translocation. Owing to the conservation of their pore regions, we were able to prepare functional pore-chimeras between the...
- Involvement of androgen receptor in nitric oxide production induced by icariin in human umbilical vein endothelial cells
[作者：Koizumi, H; Yu, J; Hashimoto, R; Ouchi, Y; Okabe, T,期刊：FEBS Letters, 页码：2440-2444 , 文章类型： Article，,卷期：2010年584-11]
- Icariin, a flavonoid isolated from Epimedii herba, stimulated phosphorylation of endothelial nitric oxide synthase (eNOS) at Ser1177, Akt (Ser473) and ERK1/2 (Thr202/Tyr204). The icariin-induced eNOS phosphorylation was ...
- Histone deacetylase 3 is selectively involved in L3MBTL2-mediated transcriptional repression
[作者：Yoo, JY; Choi, KC; Kang, H; Kim, YJ; Lee, J; Jun, WJ; Kim, MJ; Lee, YH; Lee, OH; Yoon, HG,期刊：FEBS Letters, 页码：2225-2230 , 文章类型： Article，,卷期：2010年584-11]
- This is the first report that L(3) mbt-like 2 (L3MBTL2) specifically interacts with the histone deacetylase domain of histone deacetylase 3 (HDAC3) via its MBT domain. Here, we show that L3MBTL2 selectively interacts wit...
- Evidence for a positive role of PtdIns5P in T-cell signal transduction pathways
[作者：Guittard, G; Mortier, E; Tronchere, H; Firaguay, G; Gerard, A; Zimmermann, P; Payrastre, B; Nunes, JA,期刊：FEBS Letters, 页码：2455-2460 , 文章类型： Article，,卷期：2010年584-11]
Phosphatidylinositol 5-phosphate (PtdIns5P) is emerging as a potential lipid messenger involved in several cell types, from plants to mammals. Expression of IpgD, a PtdIns(4, 5)P-2 4-phosphatase induces Src kinase and...
- NirJ, a radical SAM family member of the d(1) heme biogenesis cluster
[作者：Brindley, AA; Zajicek, R; Warren, MJ; Ferguson, SJ; Rigby, SEJ,期刊：FEBS Letters, 页码：2461-2466 , 文章类型： Article，,卷期：2010年584-11]
- NirJ is involved in the transformation of precorrin-2 into heme d(1), although its precise role in the process has not been established. The purified protein was found to contain a 4Fe-4S centre, in line with the predict...
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