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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   BRIVARACETAM SV2A Ligand Antiepileptic Drug [作者：Bestha, DP; Yang, B; Madaan, V,期刊：Drugs of the Future, 页码：165-172 , 文章类型： Article，,卷期：2010年35-3] Brivaracetam is a racetam derivative with anticonvulsant properties. It binds to synoptic vesicle glycoprotein 2A (SV2A) to produce its clinical effect. Brivaracetam is believed to have brood antiseizure activity, a rela... PEPTIDE-BASED ANTIFUNGAL THERAPIES AGAINST EMERGING INFECTIONS [作者：Matejuk, A; Leng, Q; Begum, MD; Woodle, MC; Scaria, P; Chou, ST; Mixson, AJ,期刊：Drugs of the Future, 页码：197-217 , 文章类型： Review，,卷期：2010年35-3] Acquired drug resistance to mycotic infections is rapidly emerging as a major medical problem. Opportunistic fungal infections create therapeutic challenges, particularly in high-risk immunocompromised patients with AIDS... rAAV2-CBSB-hRPE65 Ophthalmic Gene Therapy Treatment of Leber's Congenital Amaurosis [作者：Haddley, K,期刊：Drugs of the Future, 页码：173-178 , 文章类型： Article，,卷期：2010年35-3] Leber's congenital amaurosis (LCA) is a group of genetic disorders that produces defects in the retinal epithelium photoreceptors of the eye. It manifests at on early age, resulting in impaired vision and ultimately blin... RAXIBACUMAB Treatment of Anthrax Infection [作者：Adusumilli, S,期刊：Drugs of the Future, 页码：179-182 , 文章类型： Article，,卷期：2010年35-3] Raxibacumab, a human monoclonal IgG(1 lambda) antibody, is effective in the treatment of Bacillus anthracis infection or anthrax toxin exposure in animal studies due to its ability to inhibit the binding of B. anthracis ... ONCOLYTIC HERPES SIMPLEX VIRUS 1 (HSV-1) VECTORS: INCREASING TREATMENT EFFICACY AND RANGE THROUGH STRATEGIC VIRUS DESIGN [作者：Carson, J; Haddad, D; Bressman, M; Fong, Y,期刊：Drugs of the Future, 页码：183-195 , 文章类型： Review，,卷期：2010年35-3] Viruses have long been considered potential anticancer treatments. Wild-type viruses have been tested as anticancer agents in clinical trials since the 1960s. The possibility of viral oncolysis as an alternate cancer the... THERAPEUTIC TARGETS FOR ACUTE LUNG INJURY/ACUTE RESPIRATORY DISTRESS SYNDROME [作者：Sorbera, LA; Graul, AI; Sundaravinayagam, D; Dulsat, C; Rosa, E,期刊：Drugs of the Future, 页码：245-250 , 文章类型： Article，,卷期：2010年35-3] Acute lung injury (ALI) describes the numerous symptoms and syndromes associated with hypoxemic respiratory failure, the most severe form of which is acute respiratory distress syndrome (ARDS). ALI/ARDS con be triggered ... THERAPY-RELATED MYELODYSPLASTIC SYNDROMES AND ACUTE MYELOID LEUKEMIA: ETIOLOGY, PROGNOSIS AND TREATMENT [作者：Kujawski, E; Burnham, MR; Mousa, SS; Mousa, SA,期刊：Drugs of the Future, 页码：219-236 , 文章类型： Review，,卷期：2010年35-3] Acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) are a group of heterogeneous disorders characterized by abnormal hematopoiesis of myeloid cells, uni- or multilineage peripheral cytopenia, marrow dysplasia... MYOTONIC DYSTROPHY: A NEW PERSPECTIVE ON THE TREATMENT OF A MULTISYSTEMIC DISEASE [作者：Marra, C; Quaranta, D; Silvestri, C; Modoni, A,期刊：Drugs of the Future, 页码：237-244 , 文章类型： Article，,卷期：2010年35-3] So far, myotonic dystrophy (DM) has been linked to two distinct loci: DM1, associated with an abnormal CTC triplet expansion in the 3'-untranslated region of the myotonin-protein kinase gene (DMPK), and DM2, associated w... HIGHLIGHTS FROM THE 39(TH) ANNUAL MEETING OF THE SOCIETY FOR NEUROSCIENCE [作者：Arjona, A; Rosa, E; Vasiliou, S; Cole, P,期刊：Drugs of the Future, 页码：251-260 , 文章类型： Article，,卷期：2010年35-3] The 39(th) Annual Meeting of the Society for Neuroscience (October 17-21, 2009) was hosted in the city of Chicago. Over 30,000 attendees from around the world gathered in the windy city to share and discuss the latest de...