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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   AFAMELANOTIDE Melanocortin MC1 Receptor Agonist Photoprotective Agent [作者：Minder, EI,期刊：Drugs of the Future, 页码：365-372 , 文章类型： Article，,卷期：2010年35-5] Artificial tanning or induction of skin pigmentation may protect individuals with light-induced skin diseases. The paracrine skin hormone a-melanocyte-stimulating hormone (MSH), acting locally at epidermal melanocytes, i... COMPOUNDS ACTING ON THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM AS POTENTIAL REGULATORS OF AUTOIMMUNE NEUROINFLAMMATION [作者：Lee, DH; Gold, R; Linker, RA,期刊：Drugs of the Future, 页码：393-398 , 文章类型： Review，,卷期：2010年35-5] In recent years, an increasing body of evidence has shown that the renin-angiotensin-aldosterone system (RAAS) may play a crucial role as a mediator of cardiovascular and renal morbidity and in vascular inflammation. How... TANEZUMAB Anti-NCT Monoclonal Antibody Treatment of Pain Treatment of Osteoarthritis [作者：Haddley, K,期刊：Drugs of the Future, 页码：373-378 , 文章类型： Article，,卷期：2010年35-5] Current therapies for the treatment of pain and inflammation in diseases such as osteoarthritis largely rely upon the use of nonsteroidal anti-inflammatory drugs (NSAIDs) in combination with opiates such as morphine sulf... VISMODEGIB SMO Receptor Antagonist Hedgehog Signaling Inhibitor Oncolytic [作者：Haddley, K,期刊：Drugs of the Future, 页码：379-384 , 文章类型： Article，,卷期：2010年35-5] When it became apparent that aberrant hedgehog (HH) pathway signaling was a likely mediator in the development of tumors, especially basal cell carcinoma, many companies began to investigate the use of small-molecule inh... ANTIVIRAL COMPOUNDS IN THE PIPELINE TO TACKLE H1N1 INFLUENZA INFECTION [作者：Beigel, JH,期刊：Drugs of the Future, 页码：385-392 , 文章类型： Review，,卷期：2010年35-5] The recent pandemic of H1N1 has demonstrated the potential vulnerability of the human population to novel influenza viruses. While there is recent increased interest and effort in developing effective anti-influenza agen... GINSENG PHARMACOLOGY: MULTIPLE MOLECULAR TARGETS AND RECENT CLINICAL TRIALS [作者：Wahid, F; Khan, T; Subhan, F; Khan, MA; Kim, YY,期刊：Drugs of the Future, 页码：399-407 , 文章类型： Review，,卷期：2010年35-5] Ginseng has been used as a folk medicine in Far East Asian countries for several thousand years. Recently, its use has also expanded to Western countries. A number of studies provide evidence for its various pharmacologi... NEW INSIGHTS IN CHAGAS' DISEASE TREATMENT [作者：Urbina, JA,期刊：Drugs of the Future, 页码：409-419 , 文章类型： Article，,卷期：2010年35-5] Chagas' disease, caused by the kinetoplastid protozoon Trypanosoma cruzi, remains the highest parasitic disease burden in the American continent and is now spreading to nonendemic countries due to international migration... LESCH-NYHAN SYNDROME [作者：Torres, RJ; Puig, JG,期刊：Drugs of the Future, 页码：421-427 , 文章类型： Article，,卷期：2010年35-5] Lesch Nyhan syndrome (LNS) is an inborn error of purine metabolism characterized by hyperuricemia, severe action dystonia, choreoathetosis, ballismus, cognitive and attention deficits and self-injurious behavior. The syn... AMPK - A NOVEL THERAPEUTIC TARGET IN CARDIOVASCULAR DISEASES [作者：Heidrich, F; Schuenemann, J; Mokashi, SA; Schmitto, JD,期刊：Drugs of the Future, 页码：429-435 , 文章类型： Article，,卷期：2010年35-5] AMP-activated protein kinase (AMPK) is a heterotrimeric protein functioning as a sensitive molecular switch that is activated by physical and chemical stress. In the myocardium, its triggers include hypoxia, ischemia, my...