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  • Stopping treatment can reverse acquired resistance to letrozole
    [作者:Salnis, GJ; Macedo, LF; Goloubeva, O; Schayowitz, A; Brodie, AMH,期刊:Cancer research, 页码:4518-4524 , 文章类型: Article,,卷期:2008年68-12]
  • Using the intratumoral aromatase xenograft model, we have observed that despite long-lasting growth inhibition, tumors eventually begin to grow during continued letrozole treatment. In cells isolated from these long-term...
  • Underexpression of RhoH in hairy cell leukemia
    [作者:Galiegue-Zouitina, S; Delestre, L; Dupont, C; Troussard, X; Shelley, CS,期刊:Cancer research, 页码:4531-4540 , 文章类型: Article,,卷期:2008年68-12]
  • The cause of hairy cell leukemia (HCL) is unknown. Current treatments seem effective only for a limited period of time. In addition, a significant proportion of patients remain refractive to ail treatment options. These ...
  • Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas
    [作者:Peinado, H; Moreno-Bueno, G; Hardisson, D; Perez-Gomez, E; Santos, V; Mendiola, M; de Diego, JI; Nistal, M; Quintanilla, M; Portillo, F; Cano, A,期刊:Cancer research, 页码:4541-4550 , 文章类型: Article,,卷期:2008年68-12]
  • Lysyl oxidase-like 2 (Loxl2) interacts with and stabilizes Snail transcription factor, promoting epithelial-mesenchymal transition. Either Loxl2 or Snail knock-down blocks tumor growth and induces differentiation, but th...
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