- CDDO-Me inhibits breast tumor by inactivating STAT3 (vol 67, pg 4210, 2007)
[作者:Ling, X; Konopleva, M; Zeng, Z; Ruvolo, V; Stephens, LC; Schober, W; McQueen, T; Dietrich, M; Madden, TL; Andreeff, M,期刊:Cancer research, 页码:4958-4958 , 文章类型: Correction,,卷期:2008年68-12]
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- alpha-particle radioimmunotherapy of metastases (vol 68, pg 3873, 2008)
[作者:Song, H; Shahverdi, K; Huso, DL; Esaias, C; Fox, J; Liedy, A; Zhang, Z; Reilly, RT; Apostolidis, C; Morgenstern, A; Sgouros, G,期刊:Cancer research, 页码:4958-4958 , 文章类型: Correction,,卷期:2008年68-12]
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- Oncolytic vesicular stomatitis viruses are potent agents for intravesical treatment of high-risk bladder cancer
[作者:Hadaschik, BA; Zhang, K; So, AI; Fazli, L; Jia, W; Bell, JC; Gleave, ME; Rennie, PS,期刊:Cancer research, 页码:4506-4510 , 文章类型: Article,,卷期:2008年68-12]
- Bladder cancer is the second most common genitourinary malignancy. At initial diagnosis, similar to 70% of cases are nonmuscle-invasive; however, current treatment options for superficial disease are of limited efficacy ...
- Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells
[作者:Abedini, MR; Muller, EJ; Brun, J; Bergeron, R; Gray, DA; Tsang, BK,期刊:Cancer research, 页码:4511-4517 , 文章类型: Article,,卷期:2008年68-12]
- Understanding the mechanism of cisplatin (CDDP) action may improve therapeutic strategy for ovarian cancer. Although p53 and FLICE-like inhibitory protein (FLIP) are determinants of CDDP sensitivity in ovarian cancer, th...
- Stopping treatment can reverse acquired resistance to letrozole
[作者:Salnis, GJ; Macedo, LF; Goloubeva, O; Schayowitz, A; Brodie, AMH,期刊:Cancer research, 页码:4518-4524 , 文章类型: Article,,卷期:2008年68-12]
- Using the intratumoral aromatase xenograft model, we have observed that despite long-lasting growth inhibition, tumors eventually begin to grow during continued letrozole treatment. In cells isolated from these long-term...
- Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes
[作者:Lyons, JG; Patel, V; Roue, NC; Fok, SY; Soon, LL; Halliday, GM; Gutkind, JS,期刊:Cancer research, 页码:4525-4530 , 文章类型: Article,,卷期:2008年68-12]
- The transcriptional repressor Snail2 is overexpressed in head and neck squamous cell carcinomas (HNSCC) relative to nonmalignant head and neck mucosal epithelium, and in locally recurrent relative to nonrecurrent HNSCCs....
- Underexpression of RhoH in hairy cell leukemia
[作者:Galiegue-Zouitina, S; Delestre, L; Dupont, C; Troussard, X; Shelley, CS,期刊:Cancer research, 页码:4531-4540 , 文章类型: Article,,卷期:2008年68-12]
- The cause of hairy cell leukemia (HCL) is unknown. Current treatments seem effective only for a limited period of time. In addition, a significant proportion of patients remain refractive to ail treatment options. These ...
- Lysyl oxidase-like 2 as a new poor prognosis marker of squamous cell carcinomas
[作者:Peinado, H; Moreno-Bueno, G; Hardisson, D; Perez-Gomez, E; Santos, V; Mendiola, M; de Diego, JI; Nistal, M; Quintanilla, M; Portillo, F; Cano, A,期刊:Cancer research, 页码:4541-4550 , 文章类型: Article,,卷期:2008年68-12]
- Lysyl oxidase-like 2 (Loxl2) interacts with and stabilizes Snail transcription factor, promoting epithelial-mesenchymal transition. Either Loxl2 or Snail knock-down blocks tumor growth and induces differentiation, but th...
- Targeting the BAF57 SWI/SNF subunit in prostate cancer: A novel platform to control androgen receptor activity
[作者:Link, KA; Balasubramaniam, S; Sharma, A; Comstock, CES; Godoy-Tundidor, S; Powers, N; Cao, KH; Haelens, A; Claessens, F; Revelo, MP; Knudsen, KE,期刊:Cancer research, 页码:4551-4558 , 文章类型: Article,,卷期:2008年68-12]
- The androgen receptor (AIR) is critical for disseminated prostate cancer proliferation and survival. AR activity is targeted either through prevention of ligand synthesis or through the use of antagonists that bind the C...
- Serine/arginine protein-specific kinase 2 promotes leukemia cell proliferation by phosphorylating acinus and regulating cyclin A1
[作者:Jang, SW; Yang, SJ; Ehlen, A; Dong, SZ; Khoury, H; Chen, J; Persson, JL; Ye, KQ,期刊:Cancer research, 页码:4559-4570 , 文章类型: Article,,卷期:2008年68-12]
- Serine/arginine (SR) protein-specific kinase (SRPK), a family of cell cycle-regulated protein kinases, phosphorylate SR domain-containing proteins in nuclear speckles and mediate the pre-mRNA splicing. However, the physi...
- Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma
[作者:Bennett, KL; Karpenko, M; Lin, MT; Claus, R; Arab, K; Dyckhoff, G; Plinkert, P; Herpel, E; Smiraglia, D; Plass, C,期刊:Cancer research, 页码:4494-4499 , 文章类型: Article,,卷期:2008年68-12]
- Head and neck squamous cell carcinoma (HNSCC) is a very aggressive cancer. In advanced stages, the patient has poor chances of receiving effective treatment, and survival rates are low. To facilitate timely diagnosis and...
- Early-onset lymphoma and extensive embryonic apoptosis in two domain-specific Fen1 mice mutants
[作者:Larsen, E; Kleppa, L; Meza, TJ; Meza-Zepeda, LA; Rada, C; Castellanos, CG; Lien, GF; Nesse, GJ; Neuberger, MS; Laerdahl, JK; Doughty, RW; Klungland, A,期刊:Cancer research, 页码:4571-4579 , 文章类型: Article,,卷期:2008年68-12]
- Flap endonuclease 1 (FEN1) processes Okazaki fragments in lagging strand DNA synthesis, and FEN1 is involved in several DNA repair pathways. The interaction of FEN1 with the proliferating cell nuclear antigen (PCNA) proc...
- Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2
[作者:Dhar, G; Banerjee, S; Dhar, K; Tawfik, O; Mayo, MS; VanVeldhuizen, PJ; Banerjee, SK,期刊:Cancer research, 页码:4580-4587 , 文章类型: Article,,卷期:2008年68-12]
- CCN5/WISP-2 is overexpressed in noninvasive breast cancer cells and tissue samples, whereas its expression is minimal or undetected in invasive conditions. CCN5/WISP-2 has been considered as an antiinvasive gene because ...
- The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis
[作者:Heckman, CA; Holopainen, T; Wirzenius, M; Keskitalo, S; Jeltsch, M; Yla-Herttuala, S; Wedge, SR; Jurgensmeier, JM; Alitalo, K,期刊:Cancer research, 页码:4754-4762 , 文章类型: Article,,卷期:2008年68-12]
- Solid tumors express a range of factors required to sustain their growth and promote their dissemination. Among these are vascular endothelial growth factor-A (VEGF-A), the key angiogenic stimulant, and VEGF-C, a primary...
- ArgBP2-dependent signaling regulates pancreatic cell migration, adhesion, and tumorigenicity
[作者:Taieb, D; Roignot, J; Andre, F; Garcia, S; Masson, B; Pierres, A; Iovanna, JL; Soubeyran, P,期刊:Cancer research, 页码:4588-4596 , 文章类型: Article,,卷期:2008年68-12]
- The poor prognosis of pancreatic cancer is due to rapid locoregional invasion, the early development of metastases, and the limited efficacy of current therapies. To date, none of the identified oncogenes and suppressors...
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