- Ph.D. Training in Cancer Biology
[作者：Torti, FM; Altieri, D; Broach, J; Fan, H; Lotze, M; Manfredi, J; Matrisian, L; Yu, DH; Giaccia, A,期刊：Cancer research, 页码：9122-9124 , 文章类型： Article，,卷期：2008年68-22]
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- Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal
[作者：Godlewski, J; Nowicki, MO; Bronisz, A; Williams, S; Otsuki, A; Nuovo, G; RayChaudhury, A; Newton, HB; Chiocca, EA; Lawler, S,期刊：Cancer research, 页码：9125-9130 , 文章类型： Article，,卷期：2008年68-22]
- MicroRNAs (miR) show characteristic expression signatures in various cancers and can profoundly affect cancer cell behavior. We carried out miR expression profiling of human glioblastoma specimens versus adjacent brain d...
- Induction of Cytoplasmic Accumulation of p53: A Mechanism for Low Levels of Arsenic Exposure to Predispose Cells for Malignant Transformation
[作者：Huang, YL; Zhang, JL; McHenry, KT; Kim, MM; Zeng, WQ; Lopez-Pajares, V; Dibble, CC; Mizgerd, JP; Yuan, ZM,期刊：Cancer research, 页码：9131-9136 , 文章类型： Article，,卷期：2008年68-22]
- Although epidemiologic studies have linked arsenic exposure to the development of human cancer, the mechanisms underlying the tumorigenic role of arsenic remain largely undefined. We report here that treatment of cells w...
- Smokers with the CHRNA Lung Cancer-Associated Variants Are Exposed to Higher Levels of Nicotine Equivalents and a Carcinogenic Tobacco-Specific Nitrosamine
[作者：Le Marchand, L; Derby, KS; Murphy, SE; Hecht, SS; Hatsukami, D; Carmella, SG; Tiirikainen, M; Wang, HS,期刊：Cancer research, 页码：9137-9140 , 文章类型： Article，,卷期：2008年68-22]
- A locus at 15q24/15q25.1, which includes the nicotinic acetylcholine receptor A subunits 3 and 5 (CHRNA3 and CHRNA5) genes, has recently been associated with lung cancer risk, self-reported number of cigarettes smoked pe...
- Erlotinib Attenuates Homologous Recombinational Repair of Chromosomal Breaks in Human Breast Cancer Cells
[作者：Li, LP; Wang, H; Yang, ES; Arteaga, CL; Xia, F,期刊：Cancer research, 页码：9141-9146 , 文章类型： Article，,卷期：2008年68-22]
- The epidermal growth factor receptor (EGFR) family has been implicated in several cancers, including breast, and its members have become the target of novel cancer therapies. In this report, we show a novel link between ...
- Lysosomal Cathepsin B Participates in the Podosome-Mediated Extracellular Matrix Degradation and Invasion via Secreted Lysosomes in v-Src Fibroblasts
[作者：Tu, C; Ortega-Cava, CF; Chen, GS; Fernandes, ND; Cavallo-Medved, D; Sloane, BF; Band, V; Band, H,期刊：Cancer research, 页码：9147-9156 , 文章类型： Article，,卷期：2008年68-22]
- Podosomes mediate cell migration and invasion by coordinating the reorganization of actin cytoskeleton and focal matrix degradation. MMP and serine proteases have been found to function at podosomes. The lysosomal cystei...
- Bone Morphogenetic Protein-7 Inhibits Telomerase Activity, Telomere Maintenance, and Cervical Tumor Growth
[作者：Cassar, L; Li, H; Pinto, AR; Nicholls, C; Bayne, S; Liu, JP,期刊：Cancer research, 页码：9157-9166 , 文章类型： Article，,卷期：2008年68-22]
- Telomere maintenance is critical in tumor cell immortalization. Here, we report that the cytokine bone morphogenetic protein-7 (BMP7) inhibits telomerase activity that is required for telomere maintenance in cervical can...
- The Mitogen-Activated Protein Kinase Phosphatase Vaccinia H1-Related Protein Inhibits Apoptosis in Prostate Cancer Cells and Is Overexpressed in Prostate Cancer
[作者：Arnoldussen, YJ; Lorenzo, PI; Pretorius, ME; Waehre, H; Risberg, B; Maelandsmo, GM; Danielsen, HE; Saatcioglu, F,期刊：Cancer research, 页码：9255-9264 , 文章类型： Article，,卷期：2008年68-22]
- Androgen ablation during the initial stages of prostate cancer causes regression of the tumor due to an increase in apoptosis and reduced cellular proliferation. However, prostate cancer invariably progresses to an andro...
- Human Adrenomedullin Up-regulates Interleukin-13 Receptor alpha 2 Chain in Prostate Cancer In vitro and In vivo: A Novel Approach to Sensitize Prostate Cancer to Anticancer Therapy
[作者：Joshi, BH; Leland, P; Calvo, A; Green, JE; Puri, RK,期刊：Cancer research, 页码：9311-9317 , 文章类型： Article，,卷期：2008年68-22]
- Interleukin-13 (IL-13) receptor alpha 2 (IL-13R alpha 2), a high-affinity IL-13 binding subunit and a tumor antigen, is amplified in a variety of human tumor cell lines and tumors in vivo. By cDNA microarray, we have sho...
- Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma
[作者：Ding, ZB; Shi, YH; Zhou, J; Qiu, SJ; Xu, Y; Dai, Z; Shi, GM; Wang, XY; Ke, AW; Wu, B; Fan, J,期刊：Cancer research, 页码：9167-9175 , 文章类型： Article，,卷期：2008年68-22]
- Hepatocellular carcinoma (HCC) is an aggressive cancer with a poor prognosis. The role of autophagy and the prognostic value of autophagic genes are largely unknown in HCC. Here, we showed decreased expression of autopha...
- Active Cancer Immunotherapy by Anti-Met Antibody Gene Transfer
[作者：Vigna, E; Pacchiana, G; Mazzone, M; Chiriaco, C; Fontani, L; Basilico, C; Pennacchietti, S; Comoglio, PM,期刊：Cancer research, 页码：9176-9183 , 文章类型： Article，,卷期：2008年68-22]
- Gene therapy provides a still poorly explored opportunity to treat cancer by "active" immunotherapy as it enables the transfer of genes encoding antibodies directed against specific oncogenic proteins. By a bidirectional...
- Hypoxia-Inducible Factor-2 alpha Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer
[作者：Helczynska, K; Larsson, AM; Mengelbier, LH; Bridges, E; Fredlund, E; Borgquist, S; Landberg, G; Pahlman, S; Jirstrom, K,期刊：Cancer research, 页码：9212-9220 , 文章类型： Article，,卷期：2008年68-22]
- Differential regulation as well as target gene specificity of the two hypoxia-inducible factor (HIF)-alpha subunits HIF-1 alpha and HIF-2 alpha in various tumors and cell lines have been suggested. In breast cancer, the ...
- Phosphatidylinositol 3-Kinase Hyperactivation Results in Lapatinib Resistance that Is Reversed by the mTOR/Phosphatidylinositol 3-Kinase Inhibitor NVP-BEZ235
[作者：Eichhorn, PJA; Gili, M; Scaltriti, M; Serra, V; Guzman, M; Nijkamp, W; Beijersbergen, RL; Valero, V; Seoane, J; Bernards, R; Baselga, J,期刊：Cancer research, 页码：9221-9230 , 文章类型： Article，,卷期：2008年68-22]
- Small molecule inhibitors of HER2 are clinically active in women with advanced HER2-positive breast cancer who have progressed on trastuzumab treatment. However, the effectiveness of this class of agents is limited by ei...
- Small Interfering RNA Molecules Targeting Endothelin-Converting Enzyme-1 Inhibit Endothelin-1 Synthesis and the Invasive Phenotype of Ovarian Carcinoma Cells
[作者：Rayhman, O; Klipper, E; Muller, L; Davidson, B; Reich, R; Meidan, R,期刊：Cancer research, 页码：9265-9273 , 文章类型： Article，,卷期：2008年68-22]
- Endothelin-1 (ET-1) has been implicated in the progression of various cancers, including ovarian carcinoma. We found that the ovarian carcinoma cell lines ES2 and OVCAR3 and tumors from different anatomic sites expressed...
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