- Ionizing Radiation Induces Prostate Cancer Neuroendocrine Differentiation through Interplay of CREB and ATF2: Implications for Disease Progression
[作者：Deng, XH; Liu, H; Huang, JT; Cheng, L; Keller, ET; Parsons, SJ; Hu, CD,期刊：Cancer research, 页码：9663-9670 , 文章类型： Article，,卷期：2008年68-23]
- Radiation therapy is a first-line treatment for prostate cancer patients with localized tumors. Although some patients respond well to the treatment, similar to 10% of low-risk and up to 60% of high-risk prostate cancer ...
- Weekly Docetaxel (vol 68, pg 9033, 2008)
[作者：Gorelik, B; Ziv, I; Shohat, R; Wick, M; Hankins, WD; Sidransky, D; Agur, Z,期刊：Cancer research, 页码：10005-10005 , 文章类型： Correction，,卷期：2008年68-23]
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- Epigenetic Enhancement of Antigen Processing and Presentation Promotes Immune Recognition of Tumors
[作者：Setiadi, AF; Omilusik, K; David, MD; Seipp, RP; Hartikainen, J; Gopaul, R; Choi, KB; Jefferies, WA,期刊：Cancer research, 页码：9601-9607 , 文章类型： Article，,卷期：2008年68-23]
- Histone deacetylase inhibitors (HDACi) have been hailed as a powerful new class of anticancer drugs. The HDACi, trichostatin A (TSA), is thought to interfere with epigenetic control of cell cycle progression in G(1) and ...
- The ARF Tumor Suppressor Can Promote the Progression of Some Tumors
[作者：Humbey, O; Pimkina, J; Zilfou, JT; Jarnik, M; Dominguez-Brauer, C; Burgess, DJ; Eischen, CM; Murphy, ME,期刊：Cancer research, 页码：9608-9613 , 文章类型： Article，,卷期：2008年68-23]
- p14/p19(ARF) (ARF) is a tumor suppressor gene that is frequently mutated in human cancer. ARF has multiple tumor suppressor functions, some of which are mediated by signaling to p53. Surprisingly, a significant fraction ...
- Gene Therapy Using TRAIL-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells against Intracranial Glioma
[作者：Kim, SM; Lim, JY; Park, SI; Jeong, CH; Oh, JH; Jeong, M; Oh, W; Park, SH; Sung, YC; Jeun, SS,期刊：Cancer research, 页码：9614-9623 , 文章类型： Article，,卷期：2008年68-23]
- Adenovirus-mediated gene therapies against brain tumors have been limited by the difficulty in tracking glioma cells infiltrating the brain parenchyma. Human umbilical cord blood-derived mesenchymal stem cells (UCB-MSC) ...
- Metastasis Research Society-American Association for Cancer Research Joint Conference on Metastasis
[作者：Welch, DR; Cooper, CR; Hurst, DR; Lynch, CC; Martin, MD; Vaidya, KS; VanSaun, MN; Mastro, AM,期刊：Cancer research, 页码：9578-9582 , 文章类型： Article，,卷期：2008年68-23]
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- Defining the Cooperative Genetic Changes That Temporally Drive Alveolar RhabdomyosarcomaU
[作者：Naini, S; Etheridge, KT; Adam, SJ; Qualman, SJ; Bentley, RC; Counter, CM; Linardic, CM,期刊：Cancer research, 页码：9583-9588 , 文章类型： Article，,卷期：2008年68-23]
- Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and adolescence. Despite advances in therapy, patients with a histologic variant of RMS known as alveolar (aRMS) have a 5-year survival rate of <...
- Effects of Dasatinib on Src Kinase Activity and Downstream Intracellular Signaling in Primitive Chronic Myelogenous Leukemia Hematopoietic Cells
[作者：Konig, H; Copland, M; Chu, S; Jove, R; Holyoake, TL; Bhatia, R,期刊：Cancer research, 页码：9624-9633 , 文章类型： Article，,卷期：2008年68-23]
- Bcr-Abl tyrosine kinase inhibitors (TKI) are effective in inducing remissions in chronic myelogenous leukemia (CML) patients but do not eliminate primitive CML hematopoietic cells. There is a need to identify mechanisms ...
- Molecular Basis for the Critical Role of Suppressor of Cytokine Signaling-1 in Melanoma Brain Metastasis
[作者：Huang, FJ; Steeg, PS; Price, JE; Chiu, WT; Chou, PC; Me, KP; Sawaya, R; Huang, SY,期刊：Cancer research, 页码：9634-9642 , 文章类型： Article，,卷期：2008年68-23]
- Our recent study found that activation of signal transducer and activator of transcription 3 (Stat3) is up-regulated in human brain metastatic cells and contributes to brain metastasis of melanoma. However, the molecular...
- Activation of Phosphatidylinositol 3-Kinase by Membrane Localization of p110 alpha Predisposes Mammary Glands to Neoplastic Transformation
[作者：Renner, O; Blanco-Aparicio, C; Grassow, M; Canamero, M; Leal, JFM; Carnero, A,期刊：Cancer research, 页码：9643-9653 , 文章类型： Article，,卷期：2008年68-23]
- Phosphatidylinositol 3-kinases (PI3K) constitute important regulators of various signaling pathways with relevance in cancer. Enhanced activation of p110 alpha, the catalytic subunit of PI3K, was found in a high proporti...
- N-Myc Regulates a Widespread Euchromatic Program in the Human Genome Partially Independent of Its Role as a Classical Transcription Factor
[作者：Cotterman, R; Jin, VX; Krig, SR; Lemen, JM; Wey, A; Farnham, PJ; Knoepfler, PS,期刊：Cancer research, 页码：9654-9662 , 文章类型： Article，,卷期：2008年68-23]
- Myc proteins have long been modeled to operate strictly as classic gene-specific transcription factors; however, we find that N-Myc has a robust role in the human genome in regulating global cellular euchromatin, includi...
- Nuclear Bile Acid Receptor FXR Protects against Intestinal Tumorigenesis
[作者：Modica, S; Murzilli, S; Salvatore, L; Schmidt, DR; Moschetta, A,期刊：Cancer research, 页码：9589-9594 , 文章类型： Article，,卷期：2008年68-23]
- Bile acids have been considered intestinal tumor promoters, and because they are natural ligands for the nuclear receptor FXR, we examined the role of FXR in intestinal tumorigenesis. Using gain- and loss-of-function stu...
- Chemotherapy Induces Tumor Clearance Independent of Apoptosis
[作者：Guerriero, JL; Ditsworth, D; Fan, YJ; Zhao, FP; Crawford, HC; Zong, WX,期刊：Cancer research, 页码：9595-9600 , 文章类型： Article，,卷期：2008年68-23]
- Dysregulation of apoptosis is associated with the development of human cancer and resistance to anticancer therapy. The ultimate goal of cancer treatment is to selectively induce cancer cell death and overcome drug resis...
- A Polymorphism in the TC21 Promoter Associates with an Unfavorable Tamoxifen Treatment Outcome in Breast Cancer
[作者：Rokavec, M; Schroth, W; Amaral, SMC; Fritz, P; Antoniadou, L; Glavac, D; Simon, W; Schwab, M; Eichelbaum, M; Branch, H,期刊：Cancer research, 页码：9799-9808 , 文章类型： Article，,卷期：2008年68-23]
- Tamoxifen therapy is a standard in the treatment of estrogen receptor (ER)-positive breast cancer; however, its efficacy varies widely among patients. In addition to interpatient differences in the tamoxifen-metabolizing...
- SMAD6 Contributes to Patient Survival in Non-Small Cell Lung Cancer and Its Knockdown Reestablishes TGF-beta Homeostasis in Lung Cancer Cells
[作者：Jeon, HS; Dracheva, T; Yang, SH; Meerzaman, D; Fukuoka, J; Shakoori, A; Shilo, K; Travis, WD; Jen, J,期刊：Cancer research, 页码：9686-9692 , 文章类型： Article，,卷期：2008年68-23]
- The malignant transformation in several types of cancer, including lung cancer, results in a loss of growth inhibition by transforming growth factor-beta (TGF-beta). Here, we show that SMAD6 expression is associated with...
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