- Transplantation of Reprogrammed Embryonic Stem Cells Improves Visual Function in a Mouse Model for Retinitis Pigmentosa
[作者:Wang, NK; Tosi, J; Kasanuki, JM; Chou, CL; Kong, J; Parmalee, N; Wert, KJ; Allikmets, R; Lai, CC; Chien, CL; Nagasaki, T; Lin, CS; Tsang, SH,期刊:Transplantation, 页码:911-919 , 文章类型: Article,,卷期:2010年89-8]
- Background. To study whether C57BL/6J-Tyr(c-2j)/J (C2J) mouse embryonic stem (ES) cells can differentiate into retinal pigment epithelial (RPE) cells in vitro and then restore retinal function in a model for retinitis pi...
- Effects of Phlebotomy and Phenylephrine Infusion on Portal Venous Pressure and Systemic Hemodynamics During Liver Transplantation
[作者:Massicotte, L; Perrault, MA; Denault, AY; Klinck, JR; Beaulieu, D; Roy, JD; Thibeault, L; Roy, A; McCormack, M; Karakiewicz, P,期刊:Transplantation, 页码:920-927 , 文章类型: Article,,卷期:2010年89-8]
- Background. A regimen of fluid restriction, phlebotomy, vasopressors, and strict, protocol-guided product replacement has been associated with low blood product use during orthotopic liver transplantation. However, the p...
- Impact of Immunosuppressants on the Therapeutic Efficacy of In Vitro-Expanded CD4(+) CD25(+) Foxp3(+) Regulatory T Cells in Allotransplantation
[作者:Lim, DG; Koo, SK; Park, YH; Kim, Y; Kim, HM; Park, CS; Kim, SC; Han, DJ,期刊:Transplantation, 页码:928-936 , 文章类型: Article,,卷期:2010年89-8]
- Background. Although the therapeutic potential of regulatory T lymphocytes (Tregs) in preventing allograft rejection has been well documented, accumulating evidence indicates that supplemental measures, such as concomita...
- Interleukin-15 Receptor Blockade in Non-Human Primate Kidney Transplantation
[作者:Haustein, S; Kwun, J; Fechner, J; Kayaoglu, A; Faure, JP; Roenneburg, D; Torrealba, J; Knechtle, SJ,期刊:Transplantation, 页码:937-944 , 文章类型: Article,,卷期:2010年89-8]
- Background. Interleukin (IL)-15 is a chemotactic factor to T cells. It induces proliferation and promotes survival of activated T cells. IL-15 receptor blockade in mouse cardiac and islet allotransplant models has led to...
- Activation of Adventitial Fibroblasts in the Early Stage of the Aortic Transplant Vasculopathy in Rat
[作者:Ji, J; Xu, F; Li, L; Chen, R; Wang, JL; Hu, WC,期刊:Transplantation, 页码:945-953 , 文章类型: Article,,卷期:2010年89-8]
- Background. Transplant vasculopathy (TV) is the most significant obstacle to long-term success of organ transplantation. Increasing attention has been paid to the role of adventitia in vascular diseases. We evaluated the...
- Successful Human Islet Isolation and Transplantation Indicating the Importance of Class 1 Collagenase and Collagen Degradation Activity Assay
[作者:Balamurugan, AN; Breite, AG; Anazawa, T; Loganathan, G; Wilhelm, JJ; Papas, KK; Dwulet, FE; McCarthy, RC; Hering, BJ,期刊:Transplantation, 页码:954-961 , 文章类型: Article,,卷期:2010年89-8]
- Background. Purified tissue dissociation enzymes (TDEs) are critical to successful human islet isolation required for clinical transplantation, but little is known about the characteristics of the key enzymes-class I (C1...
- Beyond Histology: Lowering Human Leukocyte Antigen Antibody to Improve Renal Allograft Survival in Acute Rejection
[作者:Everly, MJ; Rebellato, LM; Ozawa, M; Briley, KP; Catrou, PG; Haisch, CE; Terasaki, PI,期刊:Transplantation, 页码:962-967 , 文章类型: Article,,卷期:2010年89-8]
- Background. The common endpoint in the treatment of antibody-mediated rejection (AMR) is functional reversal (creatinine levels). Reduction of human leukocyte antigen (HLA) antibody strength is not commonly considered as...
- Individualized Immune Monitoring of Cardiac Transplant Recipients by Noninvasive Longitudinal Cellular Immunity Tests
[作者:Israeli, M; Ben-Gal, T; Yaari, V; Valdman, A; Matz, I; Medalion, B; Battler, A; Sredni, B; Kristt, D; Klein, T,期刊:Transplantation, 页码:968-976 , 文章类型: Article,,卷期:2010年89-8]
- Background. Common immunosuppression strategies after heart transplantation (HTx) are based on accepted target drug levels, disregarding that drug levels do not correlate with the individual patient's pharmacokinetics or...
- Predictors of Renal Dysfunction at 1 Year in Heart Transplant Patients
[作者:Navarro-Manchon, J; Martinez-Dolz, L; Bonet, LA; Sanchez-Lazaro, I; Raso, RR; Grima, EZ; Ramon-Llin, JA; Fuentes, FB; Sanchez-Gomez, JM; Sanz, AS,期刊:Transplantation, 页码:977-982 , 文章类型: Article,,卷期:2010年89-8]
- Background. Renal dysfunction (RD) is one of the most significant long-term complications of heart transplantation (HT). Although RD is generally attributed to a direct effect of calcineurin inhibitors, it is more probab...
- Assessment of Allograft Fibrosis by Transient Elastography and Noninvasive Biomarker Scoring Systems in Liver Transplant Patients
[作者:Beckebaum, S; Iacob, S; Klein, CG; Dechene, A; Varghese, J; Baba, HA; Sotiropoulos, GC; Paul, A; Gerken, G; Cicinnati, VR,期刊:Transplantation, 页码:983-993 , 文章类型: Article,,卷期:2010年89-8]
- Background. This prospective, monocentric study was designed to assess the efficacy of transient elastography (TE), biochemical tests, and more complex scores in determining fibrosis stage in 157 patients transplanted fo...
- Interaction Between Everolimus and Tacrolimus in Renal Transplant Recipients: A Pharmacokinetic Controlled Trial
[作者:Pascual, J; del Castillo, D; Cabello, M; Pallardo, L; Grinyo, JM; Fernandez, AM; Brunet, M,期刊:Transplantation, 页码:994-1000 , 文章类型: Article,,卷期:2010年89-8]
- Background. Clinical data are lacking concerning therapeutic action and systemic exposure of tacrolimus (TAC) and everolimus (EVL) in a combined regimen in renal transplantation.Methods. A prospective randomized phase II...
- Cardiovascular Disease in Kidney Transplant Recipients: The Prognostic Value of Inflammatory Cytokine Genotypes
[作者:La Manna, G; Cappuccilli, ML; Cianciolo, G; Conte, D; Comai, G; Carretta, E; Scolari, MP; Stefoni, S,期刊:Transplantation, 页码:1001-1008 , 文章类型: Article,,卷期:2010年89-8]
- Background. Cardiovascular disease (CVD) represents the main cause of morbidity and mortality after renal transplantation. In view of the modern paradigm of atherosclerosis as an inflammatory disease, this study investig...
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