个性化文献订阅>文章检索

文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共11条记录   Structure of the LSm657 Complex: An Assembly Intermediate of the LSm1-7 and LSm2-8 Rings [作者：Mund, M; Neu, A; Ullmann, J; Neu, U; Sprangers, R,期刊：Journal of Molecular Biology, 页码：165-176 , 文章类型： Article，,卷期：2011年414-2] The nuclear LSm2-8 (like Sm) complex and the cytoplasmic LSm1-7 complex play a central role in mRNA splicing and degradation, respectively. The LSm proteins are related to the spliceosomal Sm proteins that form a heteroh... LEDGF/p75 TATA-Less Promoter Is Driven by the Transcription Factor Sp1 [作者：Desfarges, S; Abderrahmani, A; Hernandez-Novoa, B; Munoz, M; Ciuffi, A,期刊：Journal of Molecular Biology, 页码：177-193 , 文章类型： Article，,卷期：2011年414-2] PSIP1 (PC4 and SFRS1 interacting protein 1) encodes two splice variants: lens epithelium-derived growth factor or p75 (LEDGF/p75) and p52. PSIP1 gene products were shown to be involved in transcriptional regulation, affe... Interactions of Interleukin-8 with the Human Chemokine Receptor CXCR1 in Phospholipid Bilayers by NMR Spectroscopy [作者：Park, SH; Casagrande, F; Cho, L; Albrecht, L; Opella, SJ,期刊：Journal of Molecular Biology, 页码：194-203 , 文章类型： Article，,卷期：2011年414-2] CXCR1 is a receptor for the chemokine interleukin-8 (IL-8), a mediator of immune and inflammatory responses. Strategically located in the cell membrane, CXCR1 binds to IL-8 with high affinity and subsequently transduces ... Myosin Binding Surface on Actin Probed by Hydroxyl Radical Footprinting and Site-Directed Labels [作者：Durer, ZAO; Kamal, JKA; Benchaar, S; Chance, MR; Reisler, E,期刊：Journal of Molecular Biology, 页码：204-216 , 文章类型： Article，,卷期：2011年414-2] Actin and myosin are the two main proteins required for cell motility and muscle contraction. The structure of their strongly bound complex-rigor state is a key for delineating the functional mechanism of actomyosin moto... Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain [作者：Das, S; Raychaudhuri, M; Sen, U; Mukhopadhyay, D,期刊：Journal of Molecular Biology, 页码：217-230 , 文章类型： Article，,卷期：2011年414-2] It has been hypothesized previously that synergistic effect of both amyloid precursor protein intracellular C-terminal domain (AICD) and A beta aggregation could contribute to Alzheimer's disease pathogenesis. Structural... Crystal Structure of the LG3 Domain of Endorepellin, an Angiogenesis Inhibitor [作者：Le, BV; Kim, H; Choi, J; Kim, JH; Hahn, MJ; Lee, C; Kim, KK; Hwang, HY,期刊：Journal of Molecular Biology, 页码：231-242 , 文章类型： Article，,卷期：2011年414-2] Endorepellin, the C-terminal region of perlecan, inhibits angiogenesis by disrupting actin cytoskeleton and focal adhesions. The C-terminal laminin-like globular domain (LG3) of endorepellin directs most of this antiangi... Mapping the Deltex-Binding Surface on the Notch Ankyrin Domain Using Analytical Ultracentrifugation [作者：Allgood, AG; Barrick, D,期刊：Journal of Molecular Biology, 页码：243-259 , 文章类型： Article，,卷期：2011年414-2] The Notch signal transduction pathway controls cell fate determination during metazoan development. The Notch gene encodes a transmembrane receptor that is cleaved upon activation, liberating the Notch intracellular doma... Stepwise Expansion of the Bacteriophage phi 6 Procapsid: Possible Packaging Intermediates [作者：Nemecek, D; Cheng, NQ; Qiao, J; Mindich, L; Steven, AC; Heymann, JB,期刊：Journal of Molecular Biology, 页码：260-271 , 文章类型： Article，,卷期：2011年414-2] The initial assembly product of bacteriophage 416, the procapsid, undergoes major structural transformation during the sequential packaging of its three segments of single-stranded RNA. The procapsid, a compact icosahedr... Comparison of SARS and NL63 Papain-Like Protease Binding Sites and Binding Site Dynamics: Inhibitor Design Implications [作者：Chaudhuri, R; Tang, SS; Zhao, GJ; Lu, H; Case, DA; Johnson, ME,期刊：Journal of Molecular Biology, 页码：272-288 , 文章类型： Article，,卷期：2011年414-2] The human severe acute respiratory syndrome coronavirus (SARS-CoV) and the NL63 coronaviruses are human respiratory pathogens for which no effective antiviral treatment exists. The papain-like cysteine proteases encoded ... Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology [作者：Fleishman, SJ; Whitehead, TA; Strauch, EM; Corn, JE; Qin, SB; Zhou, HX; Mitchell, JC; Demerdash, ONA; Takeda-Shitaka, M; Terashi, G; Moal, IH; Li, XF; Bates, PA; Zacharias, M; Park, H; Ko, JS; Lee, H; Seok, C; Bourquard, T; Bernauer, J; Poupon, A; Aze, J; Soner, S; Ovali, SK; Ozbek, P; Ben Tal, N; Haliloglu, T; Hwang, H; Vreven, T; Pierce, BG; Weng, ZP; Perez-Cano, L; Pons, C; Fernandez-Recio, J; Jiang, F; Yang, F; Gong, XQ; Cao, LB; Xu, XJ; Liu, B; Wang, PW; Li, CH; Wang, CX; Robert, CH; Guharoy, M; Liu, SY; Huang, YY; Li, L; Guo, DC; Chen, Y; Xiao, Y; London, N; Itzhaki, Z; Schueler-Furman, O; Inbar, Y; Potapov, V; Cohen, M; Schreiber, G; Tsuchiya, Y; Kanamori, E; Standley, DM; Nakamura, H; Kinoshita, K; Driggers, CM; Hall, RG; Morgan, JL; Hsu, VL; Zhan, J; Yang, YD; Zhou, YQ; Kastritis, PL; Bonvin, AMJJ; Zhang, WY; Camacho, CJ; Kilambi, KP; Sircar, A; Gray, JJ; Ohue, M; Uchikoga, N; Matsuzaki, Y; Ishida, T; Akiyama, Y; Khashan, R; Bush, S; Fouches, D; Tropsha, A; Esquivel-Rodriguez,,期刊：Journal of Molecular Biology, 页码：289-302 , 文章类型： Article，,卷期：2011年414-2] The CAPRI (Critical Assessment of Predicted Interactions) and CASP (Critical Assessment of protein Structure Prediction) experiments have demonstrated the power of community-wide tests of methodology in assessing the cur... Surfactant Effects on Amyloid Aggregation Kinetics [作者：Friedman, R; Caflisch, A,期刊：Journal of Molecular Biology, 页码：303-312 , 文章类型： Article，,卷期：2011年414-2] There is strong experimental evidence of the influence of surfactants (e.g., fatty acids) on the kinetics of amyloid fibril formation. However, the structures of mixed assemblies and interactions between surfactants and ...