- A controlled pharmacogenetic trial of sibutramine on weight loss and body composition in obese or overweight adults
[作者：Grudell, ABM; Sweetser, S; Camilleri, M; Eckert, DJ; Vazquez-Roque, MI; Carlson, PJ; Burton, DD; Braddock, AE; Clark, MM; Graszer, KM; Kalsy, SA; Zinsmeister, AR,期刊：Gastroenterology, 页码：1142-1154 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Weight loss in response to sibutramine is highly variable. We assessed the association of specific markers of polymorphisms of candidate alpha 2A adrenoreceptor, S-HT transporter, and GN beta 3 genes a...
- Impact of hepatopulmonary syndrome on quality of life and survival in liver transplant candidates
[作者：Fallon, MB; Krowka, MJ; Brown, RS; Trotter, JF; Zacks, S; Roberts, KE; Shah, VH; Kaplowitz, N; Forman, L; Wille, K; Kawut, SM,期刊：Gastroenterology, 页码：1168-1175 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Hepatopulmonary syndrome (HPS) affects 10%-30% of patients with cirrhosis and portal hypertension, but the impact on functional status, quality of fife, and survival is poorly defined. We assessed the ...
- New insight into intestinal motor function via noninvasive endoluminal image analysis
[作者：Malagelada, C; De Iorio, F; Azpiroz, F; Accarino, A; Segul, S; Radeva, P; Malagelada, JR,期刊：Gastroenterology, 页码：1155-1162 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Evaluation of small bowel motility by intestinal manometry is invasive and requires expertise for interpretation. Our aim was to use capsule technology for evaluation of small bowel motor function base...
- Randomized, placebo-controlled trial of pioglitazone in nondiabetic subjects with nonalcoholic steatohepatitis
[作者：Aithal, GP; Thomas, JA; Kaye, PV; Lawson, A; Ryder, SD; Spendlove, I; Austin, AS; Freeman, JG; Morgan, L; Weeber, J,期刊：Gastroenterology, 页码：1176-1184 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease for which there is limited therapy available. Insulin sensitizing, anti-inflammatory, and antifibrotic properties of thia...
- Prospective study of dietary fiber, whole grain foods, and small intestinal cancer
[作者：Schatzkin, A; Park, Y; Leitzmann, MF; Hollenbeck, AR; Cross, AJ,期刊：Gastroenterology, 页码：1163-1167 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Although a number of epidemiologic studies have found dietary fiber and whole grains to be inversely associated with colorectal cancer incidence, studies of dietary and other risk factors for small int...
- Efficacy of serologic marker screening in identifying hepatitis B virus infection in organ, tissue, and cell donors
[作者：Challine, D; Chevaliez, S; Pawlotsky, JM,期刊：Gastroenterology, 页码：1185-1191 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Screens for serologic markers of hepatitis B virus (HBV) are used to prevent its transmission through transplantation. However, exclusion of noninfectious seropositive donors exacerbates graft shortage...
- Natural history of pediatric Crohn's disease: A population-based cohort study
[作者：Vernier-Massouille, G; Balde, M; Salleron, J; Turck, D; Dupas, JL; Mouterde, O; Merle, V; Salomez, JL; Branche, J; Marti, R; Lerebours, E; Cortot, A; Gower-Rousseau, C; Colombel, JF,期刊：Gastroenterology, 页码：1106-1113 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: The natural history of pediatric Crohn's disease and risk factors necessitating surgery have not been thoroughly described. Methods: In a geographically derived incidence cohort diagnosed from 1988 to ...
- Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease
[作者：Van Limbergent, J; Russell, RK; Drummond, HE; Aldhous, MC; Round, NK; Nimmo, ER; Smith, L; Gillett, PM; McGrogan, P; Weaver, LT; Bisset, WM; Mahdi, G; Arnott, ID; Satsangi, J; Wilsont, DC,期刊：Gastroenterology, 页码：1114-1122 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Childhood-onset inflammatory bowel disease (IBD) might be etiologically different from adult-onset IBD. We analyzed disease phenotypes and progression of childhood-onset disease and compared them with ...
- Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: A controlled randomized trial
[作者：D'Haens, GR; Vermeire, S; Van Assche, G; Noman, M; Aerden, I; Van Olmew, G; Rutgeerts, P,期刊：Gastroenterology, 页码：1123-1129 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: More than 80% of Crohn's disease (CD) patients undergoing resection suffer recurrence of their disease. Therapy with aminosalicylates, antimetabolites, or antibiotics leads to a modest reduction in the...
- A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
[作者：Sandborn, WJ; Feagan, BG; Fedorak, RN; Scherl, E; Fleisher, MR; Katz, S; Johanns, J; Blank, M; Rutgeerts, P,期刊：Gastroenterology, 页码：1130-1141 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Interleukin-12 and interleukin-23 are inflammatory cytokines implicated in Crohn's disease pathophysiology. Ustekinumab is a monoclonal antibody against the p40 subunit of interleukin-12/23. Methods: W...
- Impact of wide-angle, high-definition endoscopy in the diagnosis of colorectal neoplasia: A randomized controlled trial
[作者：Pellise, M; Fernandez-Esparrach, G; Cardenas, A; Sendino, O; Ricart, E; Vaquero, E; Gimeno-Garcia, AZ; De Miguel, C; Zabalza, M; Gines, A; Pique, JM; Llach, J; Castells, A,期刊：Gastroenterology, 页码：1062-1068 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: It is essential to optimize standard colonoscopy technique to be able to increase polyp detection. We sought to compare the performance of colonoscopy using a high-definition, wide-angle endoscope (HDE...
- Spectroscopic microvascular blood detection from the endoscopically normal colonic mucosa: Biomarker for neoplasia risk
[作者：Roy, HK; Gomes, A; Turzhitsky, V; Goldberg, MJ; Rogers, J; Ruderman, S; Young, KL; Kromine, A; Brand, RE; Jameel, M; Vakil, P; Hasabou, N; Backman, V,期刊：Gastroenterology, 页码：1069-1078 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: We previously used a novel biomedical optics technology, 4-dimensional elastically scattered light fingerprinting, to show that in experimental colon carcinogenesis the predysplastic epithelial microva...
- Role of ghrelin in the relationship between hyperphagia and accelerated gastric emptying in diabetic mice
[作者：Verhulst, PJ; De Smet, B; Saels, I; Thijs, T; Donck, LV; Moechars, D; Peeters, TL; Depoortere, I,期刊：Gastroenterology, 页码：1267-1276 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: Ghrelin is an orexigenic peptide with gastroprokinetic effects. Mice with streptozotocin (STZ)-induced diabetes exhibit hyperphagia, altered gastric emptying, and increased plasma ghrelin levels. We in...
- Overexpression of interleukin-1 beta in the murine pancreas results in chronic pancreatitis
[作者：Marrache, F; Tu, SP; Bhagat, G; Pendyala, S; Osterreicher, CH; Gordon, S; Ramanathan, V; Penz-Oesterreicher, M; Betz, KS; Song, ZG; Wang, TC,期刊：Gastroenterology, 页码：1277-1287 , 文章类型： Article，,卷期：2008年135-4]
- Background & Aims: chronic pancreatitis is a significant cause of morbidity and a known risk factor for pancreatic adenocarcinoma. Interleukin-1 beta is a proinflammatory cytokine involved in pancreatic inflammation. We ...
|