- beta-catenin promotes self-renewal of skeletal-muscle satellite cells
[作者:Perez-Ruiz, A; Ono, Y; Gnocchi, VF; Zammit, PS,期刊:Journal of cell science, 页码:1373-1382 , 文章类型: Article,,卷期:2008年121-9]
- Satellite cells are the resident stem cells of adult skeletal muscle. As with all stem cells, how the choice between self-renewal or differentiation is controlled is central to understanding their function. Here, we have...
- Slk1 is a meiosis-specific Sid2-related kinase that coordinates meiotic nuclear division with growth of the forespore membrane
[作者:Perez-Hidalgo, L; Rozalen, AE; Martin-Castellanos, C; Moreno, S,期刊:Journal of cell science, 页码:1383-1392 , 文章类型: Article,,卷期:2008年121-9]
- Septation and spore formation in fission yeast are compartmentalization processes that occur during the mitotic and meiotic cycles, and that are regulated by the septation initiation network (SIN). In mitosis, activation...
- Fibroblast migration is mediated by CD44-dependent TGF beta activation
[作者:Acharya, PS; Majumdar, S; Jacob, M; Hayden, J; Mrass, P; Weninger, W; Assoian, RK; Pure, E,期刊:Journal of cell science, 页码:1393-1402 , 文章类型: Article,,卷期:2008年121-9]
- CD44 contributes to inflammation and fibrosis in response to injury. As fibroblast recruitment is critical to wound healing, we compared cytoskeletal architecture and migration of wildtype (CD44WT) and CD44-deficient (CD...
- Pathway selection to the axon depends on multiple targeting signals in NgCAM
[作者:Yap, CC; Nokes, RL; Wisco, D; Anderson, E; Foelsch, H; Winckler, B,期刊:Journal of cell science, 页码:1514-1525 , 文章类型: Article,,卷期:2008年121-9]
- Similar to most differentiated cells, both neurons and epithelial cells elaborate distinct plasma membrane domains that contain different membrane proteins. We have previously shown that the axonal cell-adhesion molecule...
- Binding of ATP to UAP56 is necessary for mRNA export
[作者:Kota, KP; Wagner, SR; Huerta, E; Underwood, JM; Nickerson, JA,期刊:Journal of cell science, 页码:1526-1537 , 文章类型: Article,,卷期:2008年121-9]
- The major-histocompatibility-complex protein UAP56 (BAT1) is a DEAD-box helicase that is deposited on mRNA during splicing. UAP56 is retained on spliced mRNA in an exon junction complex (EJC) or, alternatively, with the ...
- TbG63, a golgin involved in Golgi architecture in Trypanosoma brucei
[作者:Ramirez, IBR; de Graffenried, CL; Ebersberger, I; Yelinek, J; He, CY; Price, A; Warren, G,期刊:Journal of cell science, 页码:1538-1546 , 文章类型: Article,,卷期:2008年121-9]
- Golgins are coiled-coil proteins that have been implicated in the structure and function of the Golgi complex. Here, we identify and characterize a trypanosomal golgin, TbG63, showing that it has a C-terminal membrane an...
- Organellar dynamics during the cell cycle of Toxoplasma gondii
[作者:Nishi, M; Hu, K; Murray, JM; Roos, DS,期刊:Journal of cell science, 页码:1559-1568 , 文章类型: Article,,卷期:2008年121-9]
- The protozoan phylum Apicomplexa encompasses similar to 5000 species of obligate intracellular parasites, including those responsible for malaria and toxoplasmosis. Rather than dividing by binary fission, apicomplexans u...
- Asymmetric localization of the adaptor protein Miranda in neuroblasts is achieved by diffusion and sequential interaction of Myosin II and VI
[作者:Erben, V; Waldhuber, M; Langer, D; Fetka, I; Jansen, RP; Petritsch, C,期刊:Journal of cell science, 页码:1403-1414 , 文章类型: Article,,卷期:2008年121-9]
- The adaptor protein Miranda plays a pivotal role in the asymmetric cell division of neuroblasts by asymmetrically segregating key differentiation factors. Miranda localization requires Myosin VI and Myosin II. The apical...
- Dynamics of an F-actin aggresome generated by the actin-stabilizing toxin jasplakinolide
[作者:Lazaro-Dieguez, F; Aguado, C; Mato, E; Sanchez-Ruiz, Y; Esteban, I; Alberch, J; Knecht, E; Egea, G,期刊:Journal of cell science, 页码:1415-1425 , 文章类型: Article,,卷期:2008年121-9]
- In this study, we report the formation of several cytoplasmic inclusion bodies composed of filamentous actin (F-actin) and generated by experimental treatments using depolymerizing or stabilizing actin toxins in neuronal...
- Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation
[作者:Luth, ES; Jun, SJ; Wessen, MK; Liadaki, K; Gussoni, E; Kunkel, LM,期刊:Journal of cell science, 页码:1426-1434 , 文章类型: Article,,卷期:2008年121-9]
- Although the contribution of bone marrow-derived cells to regenerating skeletal muscle has been repeatedly documented, there remains considerable debate as to whether this incorporation is exclusively a result of inflamm...
- Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells
[作者:Feutz, AC; Barrandon, Y; Monard, D,期刊:Journal of cell science, 页码:1435-1443 , 文章类型: Article,,卷期:2008年121-9]
- In hair follicles, dermal papilla (DP) and dermal sheath (DS) cells exhibit striking levels of plasticity, as each can regenerate both cell types. Here, we show that thrombin induces a phosphoinositide 3-kinase (PI3K)-Ak...
- ABBA regulates plasma-membrane and actin dynamics to promote radial glia extension
[作者:Saarikangas, J; Hakanen, J; Mattila, PK; Grumet, M; Salminen, M; Lappalainen, P,期刊:Journal of cell science, 页码:1444-1454 , 文章类型: Article,,卷期:2008年121-9]
- Radial glia play key roles in neuronal migration, axon guidance, and neurogenesis during development of the central nervous system. However, the molecular mechanisms regulating growth and morphology of these extended cel...
- Inhibition of beta-catenin signaling causes defects in postnatal cartilage development
[作者:Chen, M; Zhu, M; Awad, H; Li, TF; Sheu, TJ; Boyce, BF; Chen, D; O'Keefe, RJ,期刊:Journal of cell science, 页码:1455-1465 , 文章类型: Article,,卷期:2008年121-9]
- The Wnt/beta-catenin signaling pathway is essential for normal skeletal development because conditional gain or loss of function of beta-catenin in cartilage results in embryonic or early postnatal death. To address the ...
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