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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Caspase-dependent and -independent lipotoxic cell-death pathways in fission yeast [作者：Low, CP; Shui, GH; Liew, LP; Buttner, S; Madeo, F; Dawes, IW; Wenk, MR; Yang, HY,期刊：Journal of cell science, 页码：2671-2684 , 文章类型： Article，,卷期：2008年121-16] Understanding the mechanisms underlying lipid-induced cell death has significant implications in both cell biology and human diseases. Previously, we showed that fission-yeast Schizosaccharomyces pombe cells deficient in... The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes [作者：Shvets, E; Fass, E; Scherz-Shouval, R; Elazar, Z,期刊：Journal of cell science, 页码：2685-2695 , 文章类型： Article，,卷期：2008年121-16] LC3 belongs to a novel ubiquitin-like protein family that is involved in different intracellular trafficking processes, including autophagy. All members of this family share a unique three-dimensional structure composed ... Fibrillin-1 microfibril deposition is dependent on fibronectin assembly [作者：Kinsey, R; Williamson, MR; Chaudhry, S; Mellody, KT; McGovern, A; Takahashi, S; Shuttleworth, CA; Kielty, CM,期刊：Journal of cell science, 页码：2696-2704 , 文章类型： Article，,卷期：2008年121-16] Newly deposited microfibrils strongly colocalise with fibronectin in primary fibroblasts. Microfibril formation is grossly inhibited by fibronectin depletion, but rescued by supplementation with exogenous cellular fibron... The MAGUK-family protein CASK is targeted to nuclei of the basal epidermis and controls keratinocyte proliferation [作者：Ojeh, N; Pekovic, V; Jahoda, C; Maatta, A,期刊：Journal of cell science, 页码：2705-2717 , 文章类型： Article，,卷期：2008年121-16] The Ca2+/calmodulin-associated Ser/Thr kinase (CASK) binds syndecans and other cell-surface proteins through its PDZ domain and has been implicated in synaptic assembly, epithelial polarity and neuronal gene transcriptio... Signalling by neurotrophins and hepatocyte growth factor regulates axon morphogenesis by differential beta-catenin phosphorylation [作者：David, MD; Yeramian, A; Dunach, M; Llovera, M; Canti, C; de Herreros, AG; Comella, JX; Herreros, J,期刊：Journal of cell science, 页码：2718-2730 , 文章类型： Article，,卷期：2008年121-16] Tyrosine phosphorylation of beta-catenin, a component of adhesion complexes and of the Wnt pathway, affects cell adhesion, migration and gene transcription. By reducing beta-catenin availability using shRNA-mediated gene... Dynamics of component exchange at PML nuclear bodies [作者：Weidtkamp-Peters, S; Lenser, T; Negorev, D; Gerstner, N; Hofmann, TG; Schwanitz, G; Hoischen, C; Maul, G; Dittrich, P; Hemmerich, P,期刊：Journal of cell science, 页码：2731-2743 , 文章类型： Article，,卷期：2008年121-16] PML nuclear bodies (NBs) are involved in the regulation of key nuclear pathways but their biochemical function in nuclear metabolism is unknown. In this study PML NB assembly dynamics were assessed by live cell imaging a... An intact connexin N-terminus is required for function but not gap junction formation [作者：Kyle, JW; Minogue, PJ; Thomas, BC; Domowicz, DAL; Berthoud, VM; Hanck, DA; Beyer, EC,期刊：Journal of cell science, 页码：2744-2750 , 文章类型： Article，,卷期：2008年121-16] The cytoplasmic N-termini of connexins have been implicated in protein trafficking, oligomerization and channel gating. To elucidate the role of the N-terminus in connexin37 (CX37), we studied mutant constructs containin... P311 functions in an alternative pathway of lipid accumulation that is induced by retinoic acid [作者：Leung, JK; Cases, S; Vu, TH,期刊：Journal of cell science, 页码：2751-2758 , 文章类型： Article，,卷期：2008年121-16] Lipid droplets are complex and dynamic intracellular organelles that have an essential role in cholesterol and lipid homeostasis, and profoundly affect cellular structure and function. Variations in lipid-droplet composi... Distinct motifs in the chemokine receptor CCR7 regulate signal transduction, receptor trafficking and chemotaxis [作者：Otero, C; Eisele, PS; Schaeuble, K; Groettrup, M; Legler, DF,期刊：Journal of cell science, 页码：2759-2767 , 文章类型： Article，,卷期：2008年121-16] The chemokine receptor CCR7, together with its ligands CCL19 and CCL21, is responsible for the correct homing and trafficking of dendritic cells and lymphocytes to secondary lymphoid tissues. Moreover, cancer cells ca... Rab18 and Rab43 have key roles in ER-Golgi trafficking [作者：Dejgaard, SY; Murshid, A; Erman, A; Kizilay, O; Verbich, D; Lodge, R; Dejgaard, K; Ly-Hartig, TBN; Pepperkok, R; Simpson, JC; Presley, JF,期刊：Journal of cell science, 页码：2768-2781 , 文章类型： Article，,卷期：2008年121-16] Rabs and Arfs/Arls are Ras-related small GTPases of particular relevance to membrane trafficking. It is thought that these proteins regulate specific pathways through interactions with coat, motor, tether and SNARE prote... Eukaryotic chemotaxis at a glance [作者：Bagorda, A; Parent, CA,期刊：Journal of cell science, 页码：2621-2624 , 文章类型： Article，,卷期：2008年121-16] The secreted Dictyostelium protein CfaD is a chalone (vol 121, pg 2473, 2008) [作者：Bakthavatsalam, D; Brock, DA; Nikravan, NN; Houston, KD; Hatton, RD; Gomer, RH,期刊：Journal of cell science, 页码：2782-2782 , 文章类型： Correction，,卷期：2008年121-16] On the shape of migrating cells - a 'front-to-back' model [作者：Bretscher, MS,期刊：Journal of cell science, 页码：2625-2628 , 文章类型： Article，,卷期：2008年121-16] The wide range of shapes that are seen in stationary animal cells is believed to be the result of an interplay between giant filamentous complexes - largely the microfilaments and microtubules - although how this is achi... Klf5 is involved in self-renewal of mouse embryonic stem cells [作者：Parisi, S; Passaro, F; Aloia, L; Manabe, I; Nagai, R; Pastore, L; Russo, T,期刊：Journal of cell science, 页码：2629-2634 , 文章类型： Article，,卷期：2008年121-16] Self-renewal of embryonic stem cells (ESCs) is maintained by a complex regulatory mechanism involving transcription factors Oct3/4 (Pou5f1), Nanog and Sox2. Here, we report that Klf5, a Zn-finger transcription factor of ... Phosphorylation and activation of the Rac1 and Cdc42 GEF Asef in A431 cells stimulated by EGF [作者：Itoh, RE; Kiyokawa, E; Aoki, K; Nishioka, T; Akiyama, T; Matsuda, M,期刊：Journal of cell science, 页码：2635-2642 , 文章类型： Article，,卷期：2008年121-16] Rac1 has a crucial role in epidermal growth factor (EGF)induced membrane ruffling, lamellipodial protrusion, and cell migration. Several guanine nucleotide exchange factors (GEFs) including Sos1, Sos2, Tiam1 and Vav2 hav... Dynein and Star interact in EGFR signaling and ligand trafficking [作者：Iyadurai, SJP; Robinson, JT; Ma, LZ; He, YG; Mische, S; Li, MG; Brown, W; Guichard, A; Bier, E; Hays, TS,期刊：Journal of cell science, 页码：2643-2651 , 文章类型： Article，,卷期：2008年121-16] Intracellular transport and processing of ligands is critical to the activation of signal transduction pathways that guide development. Star is an essential gene in Drosophila that has been implicated in the trafficking ...