- Recruitment of mismatch repair proteins to the site of DNA damage in human cells
[作者:Hong, Z; Jiang, J; Hashiguchi, K; Hoshi, M; Lan, L; Yasui, A,期刊:Journal of cell science, 页码:3146-3154 , 文章类型: Article,,卷期:2008年121-19]
- Mismatch repair (MMR) proteins contribute to genome stability by excising DNA mismatches introduced by DNA polymerase. Although MMR proteins are also known to influence cellular responses to DNA damage, how MMR proteins ...
- Analysis of WASp function during the wound inflammatory response - live-imaging studies in zebrafish larvae
[作者:Cvejic, A; Hall, C; Bak-Maier, M; Flores, MV; Crosier, P; Redd, MJ; Martin, P,期刊:Journal of cell science, 页码:3196-3206 , 文章类型: Article,,卷期:2008年121-19]
- Wiskott-Aldrich syndrome protein (WASp) is haematopoietically restricted, and is the causative protein underlying a severe human disorder that can lead to death due to immunodeficiency and haemorrhaging. Much is known ab...
- Diphthamide modification of eEF2 requires a J-domain protein and is essential for normal development
[作者:Webb, TR; Cross, SH; McKie, L; Edgar, R; Vizor, L; Harrison, J; Peters, J; Jackson, IJ,期刊:Journal of cell science, 页码:3140-3145 , 文章类型: Article,,卷期:2008年121-19]
- The intracellular target of diphtheria toxin is a modified histidine residue, diphthamide, in the translation elongation factor, eEF2 (also known as EFT1). This enigmatic modification occurs in all eukaryotes and is prod...
- DEN1 deneddylates non-cullin proteins in vivo
[作者:Chan, Y; Yoon, J; Wu, JT; Kim, HJ; Pan, KT; Yim, J; Chien, CT,期刊:Journal of cell science, 页码:3218-3223 , 文章类型: Article,,卷期:2008年121-19]
- The ubiquitin-like protein Nedd8/Rub1 covalently modifies and activates cullin ubiquitin ligases. However, the repertoire of Nedd8-modified proteins and the regulation of protein neddylation status are not clear. The cys...
- STRA8-deficient spermatocytes initiate, but fail to complete, meiosis and undergo premature chromosome condensation
[作者:Mark, M; Jacobs, H; Oulad-Abdelghani, M; Dennefeld, C; Feret, B; Vernet, N; Codreanu, CA; Chambon, P; Ghyselinck, NB,期刊:Journal of cell science, 页码:3233-3242 , 文章类型: Article,,卷期:2008年121-19]
- We analysed the phenotypic outcome of a Stra8-null mutation on male meiosis. Because the mutant spermatocytes (1) underwent premeiotic DNA replication, (2) displayed cytological features attesting initiation of recombina...
- The voltage-gated Na+ channel Na(v)1.8 contains an ER-retention/retrieval signal antagonized by the beta 3 subunit
[作者:Zhang, ZN; Li, Q; Liu, C; Wang, HB; Wang, Q; Bao, L,期刊:Journal of cell science, 页码:3243-3252 , 文章类型: Article,,卷期:2008年121-19]
- Voltage-gated Na+ channel (Na-v) 1.8 contributes to the majority of the Na+ current that underlies the depolarizing phase of action potentials. Na(v)1.8 is mainly distributed intracellularly and its current amplitude can...
- ATP-induced P2X(7)-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages
[作者:Schachter, J; Motta, AP; Zamorano, AD; da Silva-Souza, HA; Guimaraes, MZP; Persechini, PM,期刊:Journal of cell science, 页码:3261-3270 , 文章类型: Article,,卷期:2008年121-19]
- Macrophages express the P2X(7) receptor and other nucleotide (P2) receptors, and display the phenomenon of extracellular ATP (ATP(e))-induced P2X(7)-dependent membrane permeabilization, which occurs through a poorly unde...
- p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
[作者:Soria, G; Speroni, J; Podhajcer, OL; Prives, C; Gottifredi, V,期刊:Journal of cell science, 页码:3271-3282 , 文章类型: Article,,卷期:2008年121-19]
- Although p21 upregulation is required to block cell-cycle progression following many types of genotoxic insult, UV irradiation triggers p21 proteolysis. The significance of the increased p21 turnover is unclear and might...
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