- Molecular reorganization of Cx43, Zo-1 and Src complexes during the endocytosis of gap junction plaques in response to a non-genomic carcinogen
[作者:Gilleron, J; Fiorini, C; Carette, D; Avondet, C; Falk, MM; Segretain, D; Pointis, G,期刊:Journal of cell science, 页码:4069-4078 , 文章类型: Article,,卷期:2008年121-24]
- The gap junction protein connexin 43 (Cx43) exhibits dynamic trafficking that is altered in most tumor cells and in response to carcinogen exposure. A number of connexin (Cx)-binding proteins are known to be involved in ...
- p53 is localized to a sub-nucleolar compartment after proteasomal inhibition in an energy-dependent manner
[作者:Karni-Schmidt, O; Zupnick, A; Castillo, M; Ahmed, A; Matos, T; Bouvet, P; Cordon-Cardo, C; Prives, C,期刊:Journal of cell science, 页码:4098-4105 , 文章类型: Article,,卷期:2008年121-24]
- The tumor suppressor p53 is activated in response to many forms of cellular stress leading to cell cycle arrest, senescence or apoptosis. Appropriate sub-cellular localization is essential for modulating p53 function. We...
- Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3
[作者:Evdokimov, E; Sharma, P; Lockett, SJ; Lualdi, M; Kuehn, MR,期刊:Journal of cell science, 页码:4106-4113 , 文章类型: Article,,卷期:2008年121-24]
- Conjugation of the small ubiquitin-like modifier (SUMO) to target proteins regulates numerous biological processes and has been implicated in tumorigenesis and metastasis. The three SUMO isoforms in vertebrates, SUMO1 an...
- MOR1, the Arabidopsis thaliana homologue of Xenopus MAP215, promotes rapid growth and shrinkage, and suppresses the pausing of microtubules in vivo
[作者:Kawamura, E; Wasteneys, GO,期刊:Journal of cell science, 页码:4114-4123 , 文章类型: Article,,卷期:2008年121-24]
- MOR1, the Arabidopsis thaliana homologue of the Xenopus microtubule-associated protein MAP215, is required for spatial organization of the acentrosomal microtubule arrays of plant cells. To determine how loss of MOR1 fun...
- Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages
[作者:Papakonstanti, EA; Zwaenepoel, O; Bilancio, A; Burns, E; Nock, GE; Houseman, B; Shokat, K; Ridley, AJ; Vanhaesebroeck, B,期刊:Journal of cell science, 页码:4124-4133 , 文章类型: Article,,卷期:2008年121-24]
- The class IA isoforms of phosphoinositide 3-kinase (p110 alpha, p110 beta and p110 delta) often have non-redundant functions in a given cell type. However, for reasons that are unclear, the role of a specific PI3K isofor...
- Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing
[作者:Li, SQ; Lian, SL; Moser, JJ; Fritzler, ML; Fritzler, MJ; Satoh, M; Chan, EKL,期刊:Journal of cell science, 页码:4134-4144 , 文章类型: Article,,卷期:2008年121-24]
- RNA interference is triggered by small interfering RNA and microRNA, and is a potent mechanism in post-transcriptional regulation for gene expression. GW182 ( also known as TNRC6A), an 182-kDa protein encoded by TNRC6A, ...
- Different GPI-attachment signals affect the oligomerisation of GPI-anchored proteins and their apical sorting
[作者:Paladino, S; Lebreton, S; Tivodar, S; Campana, V; Tempre, R; Zurzolo, C,期刊:Journal of cell science, 页码:4001-4007 , 文章类型: Article,,卷期:2008年121-24]
- To understand the mechanism involved in the apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) we fused to the C-terminus of GFP the GPI-anchor-attachment signal of the folate receptor (FR) ...
- The nuclear lamina promotes telomere aggregation and centromere peripheral localization during senescence of human mesenchymal stem cells
[作者:Raz, V; Vermolen, BJ; Garini, Y; Onderwater, JJM; Mommaas-Kienhuis, MA; Koster, AJ; Young, IT; Tanke, H; Dirks, RW,期刊:Journal of cell science, 页码:4018-4028 , 文章类型: Article,,卷期:2008年121-24]
- Ex vivo, human mesenchymal stem cells (hMSCs) undergo spontaneous cellular senescence after a limited number of cell divisions. Intranuclear structures of the nuclear lamina were formed in senescent hMSCs, which are iden...
- AQP4 knockout impairs proliferation, migration and neuronal differentiation of adult neural stem cells
[作者:Kong, H; Fan, Y; Xie, J; Ding, JH; Sha, LL; Shi, XR; Sun, XL; Hu, G,期刊:Journal of cell science, 页码:4029-4036 , 文章类型: Article,,卷期:2008年121-24]
- Aquaporin-4 (AQP4), a key molecule for maintaining water and ion homeostasis in the central nervous system, is expressed in adult neural stem cells (ANSCs) as well as astrocytes. However, little is known about the functi...
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