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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共13条记录   Contribution of a TANK-Binding Kinase 1-Interferon (IFN) Regulatory Factor 7 Pathway to IFN-gamma-Induced Gene Expression [作者：Farlik, M; Rapp, B; Marie, I; Levy, DE; Jamieson, AM; Decker, T,期刊：Molecular and Cellular Biology, 页码：1032-1043 , 文章类型： Article，,卷期：2012年32-6] Signal transducers and activators of transcription (STATs) and interferon regulatory factors (IRFs) share common target genes. Here we show that the Irf7 gene is regulated by transcription factors STAT1 and IRF9 in respo... Dynamic Loss of H2B Ubiquitylation without Corresponding Changes in H3K4 Trimethylation during Myogenic Differentiation [作者：Vethantham, V; Yang, Y; Bowman, C; Asp, P; Lee, JH; Skalnik, DG; Dynlacht, BD,期刊：Molecular and Cellular Biology, 页码：1044-1055 , 文章类型： Article，,卷期：2012年32-6] Ubiquitylation of H2B on lysine 120 (H2Bub) is associated with active transcriptional elongation. H2Bub has been implicated in histone cross talk and is generally regarded to be a prerequisite for trimethylation of histo... CD2AP Regulates SUMOylation of CIN85 in Podocytes [作者：Tossidou, I; Niedenthal, R; Klaus, M; Teng, BN; Worthmann, K; King, BL; Peterson, KJ; Haller, H; Schiffer, M,期刊：Molecular and Cellular Biology, 页码：1068-1079 , 文章类型： Article，,卷期：2012年32-6] Podocytes are highly differentiated and polarized epithelial cells located on the visceral side of the glomerulus. They form an indispensable component of the glomerular filter, the slit diaphragm, formed by several tran... T-Cell Protein Tyrosine Phosphatase Regulates Bone Resorption and Whole-Body Insulin Sensitivity through Its Expression in Osteoblasts [作者：Zee, T; Settembre, C; Levine, RL; Karsenty, G,期刊：Molecular and Cellular Biology, 页码：1080-1088 , 文章类型： Article，,卷期：2012年32-6] Insulin signaling in osteoblasts contributes to whole-body glucose homeostasis in the mouse and in humans by increasing the activity of osteocalcin. The osteoblast insulin signaling cascade is negatively regulated by ESP... Evidence Providing New Insights into TOB-Promoted Deadenylation and Supporting a Link between TOB's Deadenylation-Enhancing and Antiproliferative Activities [作者：Ezzeddine, N; Chen, CYA; Shyu, AB,期刊：Molecular and Cellular Biology, 页码：1089-1098 , 文章类型： Article，,卷期：2012年32-6] The mammalian TOB1 and TOB2 proteins have emerged as key players in repressing cell proliferation. Accumulating evidence indicates that TOBs regulate mRNA deadenylation. A recruitment model was proposed in which TOBs pro... Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is a Cell-Autonomous Regulator of Lipolysis Essential for Adipocyte Differentiation [作者：Chen, WQ; Chang, B; Saha, P; Hartig, SM; Li, L; Reddy, VT; Yang, YS; Yechoor, V; Mancini, MA; Chan, L,期刊：Molecular and Cellular Biology, 页码：1099-1111 , 文章类型： Article，,卷期：2012年32-6] Mutations in BSCL2 underlie human congenital generalized lipodystrophy. We inactivated Bscl2 in mice to examine the mechanisms whereby absence of Bscl2 leads to adipose tissue loss and metabolic disorders. Bscl2(-/-) mic... snRNA 3 ' End Formation Requires Heterodimeric Association of Integrator Subunits [作者：Albrecht, TR; Wagner, EJ,期刊：Molecular and Cellular Biology, 页码：1112-1123 , 文章类型： Article，,卷期：2012年32-6] The Integrator Complex is a group of proteins responsible for the endonucleolytic cleavage of primary small nuclear RNA (snRNA) transcripts within the nucleus. Integrator subunits 9 and 11 (IntS9/11) are thought to conta... Identification of an AAA ATPase VPS4B-Dependent Pathway That Modulates Epidermal Growth Factor Receptor Abundance and Signaling during Hypoxia [作者：Lin, HH; Li, X; Chen, JL; Sun, XZ; Cooper, FN; Chen, YR; Zhang, WY; Chung, YY; Li, A; Cheng, CT; Yang, LX; Deng, XT; Liu, XY; Yen, Y; Johnson, DL; Shih, HM; Yang, A; Ann, DK,期刊：Molecular and Cellular Biology, 页码：1124-1138 , 文章类型： Article，,卷期：2012年32-6] VPS4B, an AAA ATPase (ATPase associated with various cellular activities), participates in vesicular trafficking and autophagosome maturation in mammalian cells. In solid tumors, hypoxia is a common feature and an indica... RYBP Represses Endogenous Retroviruses and Preimplantation- and Germ Line-Specific Genes in Mouse Embryonic Stem Cells [作者：Hisada, K; Sanchez, C; Endo, TA; Endoh, M; Roman-Trufero, M; Sharif, J; Koseki, H; Vidal, M,期刊：Molecular and Cellular Biology, 页码：1139-1149 , 文章类型： Article，,卷期：2012年32-6] Polycomb repressive complexes (PRCs) are important chromatin regulators of embryonic stem (ES) cell function. RYBP binds Polycomb H2A monoubiquitin ligases Ring1A and Ring1B and has been suggested to assist PRC localizat... Paf1 Restricts Gcn4 Occupancy and Antisense Transcription at the ARG1 Promoter [作者：Crisucci, EM; Arndt, KM,期刊：Molecular and Cellular Biology, 页码：1150-1163 , 文章类型： Article，,卷期：2012年32-6] The conserved Paf1 complex negatively regulates the expression of numerous genes, yet the mechanisms by which it represses gene expression are not well understood. In this study, we use the ARG1 gene as a model to invest... Dcp2 Decapping Protein Modulates mRNA Stability of the Critical Interferon Regulatory Factor (IRF) IRF-7 [作者：Li, Y; Dai, JH; Song, MG; Fitzgerald-Bocarsly, P; Kiledjian, M,期刊：Molecular and Cellular Biology, 页码：1164-1172 , 文章类型： Article，,卷期：2012年32-6] The mammalian Dcp2 mRNA-decapping protein functions primarily on a subset of mRNAs in a transcript-specific manner. Here we show that Dcp2 is an important modulator of genes involved in the type I interferon (IFN) respon... Sam50 Functions in Mitochondrial Intermembrane Space Bridging and Biogenesis of Respiratory Complexes [作者：Ott, C; Ross, K; Straub, S; Thiede, B; Gotz, M; Goosmann, C; Krischke, M; Mueller, MJ; Krohne, G; Rudel, T; Kozjak-Pavlovic, V,期刊：Molecular and Cellular Biology, 页码：1173-1188 , 文章类型： Article，,卷期：2012年32-6] Mitochondria possess an outer membrane (OMM) and an inner membrane (IMM), which folds into invaginations called cristae. Lipid composition, membrane potential, and proteins in the IMM influence organization of cristae. H... RNA Profiling and Chromatin Immunoprecipitation-Sequencing Reveal that PTF1a Stabilizes Pancreas Progenitor Identity via the Control of MNX1/HLXB9 and a Network of Other Transcription Factors [作者：Thompson, N; Gesina, E; Scheinert, P; Bucher, P; Grapin-Botton, A,期刊：Molecular and Cellular Biology, 页码：1189-1199 , 文章类型： Article，,卷期：2012年32-6] Pancreas development is initiated by the specification and expansion of a small group of endodermal cells. Several transcription factors are crucial for progenitor maintenance and expansion, but their interactions and th...