- Novel Roles of Caenorhabditis elegans Heterochromatin Protein HP1 and Linker Histone in the Regulation of Innate Immune Gene Expression
[作者：Studencka, M; Konzer, A; Moneron, G; Wenzel, D; Opitz, L; Salinas-Riester, G; Bedet, C; Kruger, M; Hell, SW; Wisniewski, JR; Schmidt, H; Palladino, F; Schulze, E; Jedrusik-Bode, M,期刊：Molecular and Cellular Biology, 页码：251-265 , 文章类型： Article，,卷期：2012年32-2]
- Linker histone (H1) and heterochromatin protein 1 (HP1) are essential components of heterochromatin which contribute to the transcriptional repression of genes. It has been shown that the methylation mark of vertebrate h...
- RAD6 Regulates the Dosage of p53 by a Combination of Transcriptional and Posttranscriptional Mechanisms
[作者：Chen, S; Wang, DL; Liu, Y; Zhao, L; Sun, FL,期刊：Molecular and Cellular Biology, 页码：576-587 , 文章类型： Article，,卷期：2012年32-2]
- Maintaining an appropriate cellular concentration of p53 is critical for cell survival and normal development in various organisms. In this study, we provide evidence that the human E2 ubiquitin-conjugating enzyme RAD6 p...
- The RecQ4 Orthologue Hrq1 Is Critical for DNA Interstrand Cross-Link Repair and Genome Stability in Fission Yeast
[作者：Groocock, LM; Prudden, J; Perry, JJP; Boddy, MN,期刊：Molecular and Cellular Biology, 页码：276-287 , 文章类型： Article，,卷期：2012年32-2]
- Of the five human RecQ family helicases, RecQ4, BLM, and WRN suppress distinct genome instability-linked diseases with severe phenotypes, often with indeterminate etiologies. Here, we functionally define Hrq1, a novel or...
- Frat Is a Phosphatidylinositol 3-Kinase/Akt-Regulated Determinant of Glycogen Synthase Kinase 3 beta Subcellular Localization in Pluripotent Cells
[作者：Bechard, M; Trost, R; Singh, AM; Dalton, S,期刊：Molecular and Cellular Biology, 页码：288-296 , 文章类型： Article，,卷期：2012年32-2]
- Suppressing the activity of Gsk3 beta is critical for maintenance of murine pluripotent stem cells. In murine embryonic stem cells (mESCs), Gsk3 beta is inhibited by multiple mechanisms, including its inhibitory phosphor...
- Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway
[作者：Lin, X; Yang, XS; Li, Q; Ma, YL; Cui, S; He, DC; Lin, X; Schwartz, RJ; Chang, J,期刊：Molecular and Cellular Biology, 页码：297-308 , 文章类型： Article，,卷期：2012年32-2]
- Protein tyrosine phosphatase-like A (PTPLa) has been implicated in skeletal myogenesis and cardiogenesis. Mutations in PTPLa correlated with arrhythmogenic right ventricular dysplasia in humans and congenital centronucle...
- Mitochondrial Fission Contributes to Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
[作者：Jheng, HF; Tsal, PJ; Guo, SM; Rua, LH; Chang, CS; Su, IJ; Chang, CR; Tsai, YS,期刊：Molecular and Cellular Biology, 页码：309-319 , 文章类型： Article，,卷期：2012年32-2]
- Mitochondrial dysfunction in skeletal muscle has been implicated in the development of insulin resistance and type 2 diabetes. Considering the importance of mitochondrial dynamics in mitochondrial and cellular functions,...
- Identification of a Src Tyrosine Kinase/SIAH2 E3 Ubiquitin Ligase Pathway That Regulates C/EBP delta Expression and Contributes to Transformation of Breast Tumor Cells
[作者：Sarkar, TR; Sharan, S; Wang, J; Pawar, SA; Cantwell, CA; Johnson, PF; Morrison, DK; Wang, JM; Sterneck, E,期刊：Molecular and Cellular Biology, 页码：320-332 , 文章类型： Article，,卷期：2012年32-2]
- The transcription factor CCAAT/enhancer-binding protein delta (C/EBP delta, CEBPD) is a tumor suppressor that is downregulated during breast cancer progression but may also promote metastasis. Here, we have investigated ...
- Satb1 Ablation Alters Temporal Expression of Immediate Early Genes and Reduces Dendritic Spine Density during Postnatal Brain Development
[作者：Balamotis, MA; Tamberg, N; Woo, YJ; Li, JC; Davy, B; Kohwi-Shigematsu, T; Kohwi, Y,期刊：Molecular and Cellular Biology, 页码：333-347 , 文章类型： Article，,卷期：2012年32-2]
- Complex behaviors, such as learning and memory, are associated with rapid changes in gene expression of neurons and subsequent formation of new synaptic connections. However, how external signals are processed to drive s...
- TIN2 Stability Is Regulated by the E3 Ligase Siah2
[作者：Bhanot, M; Smith, S,期刊：Molecular and Cellular Biology, 页码：376-384 , 文章类型： Article，,卷期：2012年32-2]
- Telomeres are coated by shelterin, a six-subunit complex that is required for protection and replication of chromosome ends. The central subunit TIN2, with binding sites to three subunits (TRF1, TRF2, and TPP1), is essen...
- The Forkhead Transcription Factor FOXK2 Promotes AP-1-Mediated Transcriptional Regulation
[作者：Ji, ZL; Donaldson, IJ; Liu, JR; Hayes, A; Zeef, LAH; Sharrocks, AD,期刊：Molecular and Cellular Biology, 页码：385-398 , 文章类型： Article，,卷期：2012年32-2]
- The transcriptional control circuitry in eukaryotic cells is complex and is orchestrated by combinatorially acting transcription factors. Forkhead transcription factors often function in concert with heterotypic transcri...
- Integration of Regulatory Networks by NKX3-1 Promotes Androgen-Dependent Prostate Cancer Survival
[作者：Tan, PY; Chang, CW; Chng, KR; Wansa, KDSA; Sung, WK; Cheung, E,期刊：Molecular and Cellular Biology, 页码：399-414 , 文章类型： Article，,卷期：2012年32-2]
- The NKX3-1 gene is a homeobox gene required for prostate tumor progression, but how it functions is unclear. Here, using chromatin immunoprecipitation coupled to massively parallel sequencing (ChIP-seq) we showed that NK...
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