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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共17条记录   FHA Domain pThr Binding Specificity: It's All about Me [作者：Coquelle, N; Glover, JNM,期刊：Structure, 页码：1549-1550 , 文章类型： Editorial Material，,卷期：2010年18-12] The FHA domain is a phospho-peptide binding module involved in a wide range of cellular pathways, with a striking specificity for phospho-threonine over phospho-serine binding partners. Biochemical, structural, and dynam... Finding the Path in an RNA Folding Landscape [作者：Boodram, SN; Johnson, PE,期刊：Structure, 页码：1550-1551 , 文章类型： Editorial Material，,卷期：2010年18-12] In this issue of Structure, Reymond et al. (2010) combine molecular and computational biology approaches to provide structural details for intermediates in the folding pathway of the hepatitis delta virus ribozyme. Toward a Structural Understanding of Art Family: Effector Specificity [作者：Chavrier, P; Menetrey, J,期刊：Structure, 页码：1552-1558 , 文章类型： Review，,卷期：2010年18-12] Art family proteins are critical regulators of intracellular trafficking and actin cytoskeleton dynamics. To carry out their cellular functions, Arf family proteins interact with various effectors that differ in nature a... A View into the Blind Spot: Solution NMR Provides New Insights into Signal Transduction Across the Lipid Bilayer [作者：Call, ME; Chou, JJ,期刊：Structure, 页码：1559-1569 , 文章类型： Review，,卷期：2010年18-12] One of the most fundamental problems in cell biology concerns how cells communicate with their surroundings through surface receptors. The last few decades have seen major advances in understanding the mechanisms of rece... The Third Conformation of p38 alpha MAP Kinase Observed in Phosphorylated p38 alpha and in Solution [作者：Akella, R; Min, XS; Wu, QO; Gardner, KH; Goldsmith, EJ,期刊：Structure, 页码：1571-1578 , 文章类型： Article，,卷期：2010年18-12] MAPKs engage substrates, MAP2Ks, and phosphatases via a docking groove in the C-terminal domain of the kinase. Prior crystallographic studies on the unphosphorylated MAPKs p38 alpha and ERK2 defined the docking groove an... In Vivo Assembly of an Archaeal Virus Studied with Whole-Cell Electron Cryotomography [作者：Fu, CY; Wang, K; Gan, L; Lanman, J; Khayat, R; Young, MJ; Jensen, GJ; Doerschuk, PC; Johnson, JE,期刊：Structure, 页码：1579-1586 , 文章类型： Article，,卷期：2010年18-12] We applied whole-cell electron cryotomography to the archaeon Sulfolobus infected by Sulfolobus turreted icosahedral virus (STIV), which belongs to the PRD1-Adeno lineage of dsDNA viruses. STIV infection induced the form... Structural and Functional Analysis of Phosphothreonine-Dependent FHA Domain Interactions [作者：Pennell, S; Westcott, S; Ortiz-Lombardia, M; Patel, D; Li, JJ; Nott, TJ; Mohammed, D; Buxton, RS; Yaffe, MB; Verma, C; Smerdon, SJ,期刊：Structure, 页码：1587-1595 , 文章类型： Article，,卷期：2010年18-12] FHA domains are well established as phospho-dependent binding modules mediating signal transduction in Ser/Thr kinase signaling networks in both eukaryotic and prokaryotic species. Although they are unique in binding exc... Nanometer Propagation of Millisecond Motions in V-Type Allostery [作者：Lipchock, JM; Loria, JP,期刊：Structure, 页码：1596-1607 , 文章类型： Article，,卷期：2010年18-12] Imidazole glycerol phosphate synthase (IGPS) is a V-type allosteric enzyme, which is catalytically inactive for glutamine hydrolysis until the allosteric effector, N'-[(5'-phosphoribulosyl)formimino]-5-aminoimidazole-4-c... Developing Three-Dimensional Models of Putative-Folding Intermediates of the HDV Ribozyme [作者：Reymond, C; Levesque, D; Bisaillon, M; Perreault, JP,期刊：Structure, 页码：1608-1616 , 文章类型： Article，,卷期：2010年18-12] Both the role and the interacting partners of an RNA molecule can change depending on its tertiary structure. Consequently, it is important to be able to accurately predict the complete folding pathway of an RNA molecule... Structural Basis for the Differential Effects of CaBP1 and Calmodulin on Ca(v)1.2 Calcium-Dependent Inactivation [作者：Findeisen, F; Minor, DL,期刊：Structure, 页码：1617-1631 , 文章类型： Article，,卷期：2010年18-12] Calcium-binding protein 1 (CaBP1), a calmodulin (CaM) homolog, endows certain voltage-gated calcium channels (Gays) with unusual properties. CaBP1 inhibits Ca(v)1.2 calcium-dependent inactivation (CDI) and introduces cal... Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody [作者：Freeman, MM; Seaman, MS; Rits-Volloch, S; Hong, XG; Kao, CY; Ho, DD; Chen, B,期刊：Structure, 页码：1632-1641 , 文章类型： Article，,卷期：2010年18-12] lbalizumab is a humanized, anti-CD4 monoclonal antibody. It potently blocks HIV-1 infection and targets an epitope in the second domain of CD4 without interfering with immune functions mediated by interaction of CD4 with... Structural Characterization of the DAXX N-Terminal Helical Bundle Domain and Its Complex with Rassf1C [作者：Escobar-Cabrera, E; Lau, DKW; Giovinazzi, S; Ishov, AM; McIntosh, LP,期刊：Structure, 页码：1642-1653 , 文章类型： Article，,卷期：2010年18-12] DAXX is a scaffold protein with diverse roles including transcription and cell cycle regulation. Using NMR spectroscopy, we demonstrate that the C-terminal half of DAXX is intrinsically disordered, whereas a folded domai... Structural Diversity in Integrin/Talin Interactions [作者：Anthis, NJ; Wegener, KL; Critchley, DR; Campbell, ID,期刊：Structure, 页码：1654-1666 , 文章类型： Article，,卷期：2010年18-12] The adhesion of integrins to the extracellular matrix is regulated by binding of the cytoskeletal protein talin to the cytoplasmic tail of the beta-integrin subunit. Structural studies of this interaction have hitherto l... Allosteric Activation Mechanism of the Mycobacterium tuberculosis Receptor Ser/Thr Protein Kinase, PknB [作者：Lombana, TN; Echols, N; Good, MC; Thomsen, ND; Ng, HL; Greenstein, AE; Falick, AM; King, DS; Alber, T,期刊：Structure, 页码：1667-1677 , 文章类型： Article，,卷期：2010年18-12] The essential Mycobacterium tuberculosis Ser/Thr protein kinase (STPK), PknB, plays a key role in regulating growth and division, but the structural basis of activation has not been defined. Here, we provide biochemical ... Toward a Structure Determination Method for Biomineral-Associated Protein Using Combined Solid-State NMR and Computational Structure Prediction [作者：Masica, DL; Ash, JT; Ndao, M; Drobny, GP; Gray, JJ,期刊：Structure, 页码：1678-1687 , 文章类型： Article，,卷期：2010年18-12] Protein-biomineral interactions are paramount to materials production in biology, including the mineral phase of hard tissue. Unfortunately, the structure of biomineral-associated proteins cannot be determined by X-ray c... Structure of the PTEN-like Region of Auxilin, a Detector of Clathrin-Coated Vesicle Budding (Vol 18, 1191, 2010) [作者：Guan, R; Dai, H; Harrison, SC; Kirchhausen, T,期刊：Structure, 页码：1688-1688 , 文章类型： Correction，,卷期：2010年18-12]