- Targeting the HGF/Met signaling pathway in cancer therapy
[作者:Cecchi, F; Rabe, DC; Bottaro, DP,期刊:Expert Opinion on Therapeutic Targets, 页码:553-572 , 文章类型: Review,,卷期:2012年16-6]
- Introduction: Under normal conditions, hepatocyte growth factor (HGF)-induced activation of its cell surface receptor, the Met tyrosine kinase (TK), is tightly regulated by paracrine ligand delivery, ligand activation at...
- Nur77: a potential therapeutic target in cancer
[作者:To, SKY; Zeng, JZ; Wong, AST,期刊:Expert Opinion on Therapeutic Targets, 页码:573-585 , 文章类型: Review,,卷期:2012年16-6]
- Introduction: The orphan nuclear receptor Nur77 (also known as NR4A1, NGFIB, TR3, TIS1, NAK-1, or N10) is a unique transcription factor encoded by an immediate early gene. Nur77 signaling is deregulated in many cancers a...
|