- Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway
[作者：Shamimi-Noori, S; Yeow, WS; Ziauddin, MF; Xin, H; Tran, TLN; Xie, J; Loehfelm, A; Patel, P; Yang, J; Schrump, DS; Fang, BL; Nguyen, DM,期刊：Cancer gene therapy, 页码：356-370 , 文章类型： Article，,卷期：2008年15-6]
- Despite adequately expressing tumor necrosis factor-related apoptosis-inducing ligand ( TRAIL) receptors DR4/ DR5, malignant cells are frequently refractory to the cytotoxic effect of this apoptosis-inducing ligand. The ...
- Adenovirus-mediated restoration of expression of the tumor suppressor gene DLC1 inhibits the proliferation and tumorigenicity of aggressive, androgen-independent human prostate cancer cell lines: prospects for gene therapy
[作者：Guan, M; Tripathi, V; Zhou, X; Popescu, NC,期刊：Cancer gene therapy, 页码：371-381 , 文章类型： Article，,卷期：2008年15-6]
- Our recent study showing highly recurrent loss of function of DLC1 ( deleted in liver cancer 1), a tumor suppressor gene in primary prostate carcinoma ( PCA), implicates this gene in the pathogenesis of this disease. To ...
- Genetically engineered T cells expressing a HER2-specific chimeric receptor mediate antigen-specific tumor regression
[作者：Li, S; Yang, J; Urban, FA; MacGregor, JN; Hughes, DPM; Chang, AE; Mcdonagh, KT; Li, Q,期刊：Cancer gene therapy, 页码：382-392 , 文章类型： Article，,卷期：2008年15-6]
- In this report, we developed a chimeric receptor ( N29 gamma chR) involving the single chain Fv ( scFv) derived from N29 monoclonal antibody ( mAb) specific for p185HER2 and characterized the therapeutic efficacy of prim...
- Tumor-targeting prodrug-activating bacteria for cancer therapy
[作者：Cheng, CM; Lu, YL; Chuang, KH; Hung, WC; Shiea, J; Su, YC; Kao, CH; Chen, BM; Roffler, S; Cheng, TL,期刊：Cancer gene therapy, 页码：393-401 , 文章类型： Article，,卷期：2008年15-6]
- Increasing the specificity of chemotherapy may improve the efficacy of cancer treatment. Toward this aim, we developed a strain of bacteria to express enzymes for selective prodrug activation and non-invasive imaging in ...
- Silencing Livin gene expression to inhibit proliferation and enhance chemosensitivity in tumor cells
[作者：Wang, R; Lin, F; Wang, X; Gao, P; Dong, K; Zou, AM; Cheng, SY; Wei, SH; Zhang, HZ,期刊：Cancer gene therapy, 页码：402-412 , 文章类型： Article，,卷期：2008年15-6]
- Livin, a novel member of the human inhibitors of apoptosis protein ( IAP) family, plays an important role in tumor progression and occurrence by inhibiting cell apoptosis. It is selectively expressed in the most common h...
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