- Conjugated eicosapentaenoic acid inhibits human topoisomerase IB with a mechanism different from camptothecin
[作者:Castelli, S; Campagna, A; Vassallo, O; Tesauro, C; Fiorani, P; Tagliatesta, P; Oteri, F; Falconi, M; Majumder, HI; Desideri, A,期刊:Archives of Biochemistry and Biophysics , 页码:103-110 , 文章类型: Article,,卷期:2009年486-2]
- Conjugated eicosapentaenoic acid (cEPA) has been found to have antitumor effects which has been ascribed to their ability to inhibit DNA topoisomerases and DNA polymerases. We here show that cEPA inhibits the catalytic a...
- Role of matrix metalloproteinase-9 in lipopolysaccharide-induced mucin production in human airway epithelial cells
[作者:Wang, YH; Yao, S; Ka, L; Zhang, PH; Wang, GF; Lei, G; Bai, CX,期刊:Archives of Biochemistry and Biophysics , 页码:111-118 , 文章类型: Article,,卷期:2009年486-2]
- Matrix metalloproteinases (MMPs) have been found to be involved in the pathogenesis of inflammatory airway diseases. However, the role of MMPs in lipopolysaccharide (LPS)-induced mucin overproduction remains unclear. We ...
- Thermal stability and redox properties of M. tuberculosis CuSOD
[作者:D'Orazio, M; Cervoni, L; Giartosio, A; Rotilio, G; Battistoni, A,期刊:Archives of Biochemistry and Biophysics , 页码:119-124 , 文章类型: Article,,卷期:2009年486-2]
- The superoxide dismutase from Mycobacterium tuberculosis is the only Cu-containing Superoxide dismutase that lacks zinc in the active site. To explore the structural properties of this unusual enzyme, we have investigate...
- Structure-function correlation of human programmed cell death 5 protein
[作者:Yao, HW; Xu, LJ; Feng, YG; Liu, DS; Chen, YY; Wang, JF,期刊:Archives of Biochemistry and Biophysics , 页码:141-149 , 文章类型: Article,,卷期:2009年486-2]
- Human programmed cell death 5 (PDCD5) is a translocatory protein playing ail important role in the apoptotic process of cells. Although there are accumulated data about PDCD5 function, the correlation of the structure wi...
- The cytoplasmic domain of influenza M2 protein interacts with caveolin-1
[作者:Peng, Z; Fan, W; Lu, L; Huang, JH; Chen, YH,期刊:Archives of Biochemistry and Biophysics , 页码:150-154 , 文章类型: Article,,卷期:2009年486-2]
- The cytoplasmic domain of influenza M2 protein (M2c) consists of 54 amino acid (aa) residues from aa44 to aa97. In this paper, M2c and its deletion mutant M2c(Delta 47-55) were expressed using prokaryotic expression syst...
- Multiple molecular targets of resveratrol: Anti-carcinogenic mechanisms
[作者:Athar, M; Back, JH; Kopelovich, L; Bickers, DR; Kim, AL,期刊:Archives of Biochemistry and Biophysics , 页码:95-102 , 文章类型: Review,,卷期:2009年486-2]
- Plant-derived polyphenolic compounds, such as the stilbene resveratrol (trans-3,4',5-trihydroxystilbene), have been identified as potent anti-cancer agents. Extensive in vitro studies revealed multiple intracellular targ...
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