- Redox properties of the oxygen-detoxifying flavodiiron protein from the human parasite Giardia intestinalis
[作者:Vicente, JB; Testa, F; Mastronicola, D; Forte, E; Sarti, P; Teixeira, M; Giuffre, A,期刊:Archives of Biochemistry and Biophysics , 页码:9-13 , 文章类型: Article,,卷期:2009年488-1]
- Flavodiiron proteins (FDPs) are enzymes identified in prokaryotes and a few pathogenic protozoa, which protect microorganisms by reducing O-2 to H2O and/or NO to N2O. Unlike most prokaryotic FDPs, the protozoan enzymes f...
- Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5
[作者:Li, XJ; Lu, C; Stewart, M; Xu, HY; Strong, RK; Igumenova, T; Li, PW,期刊:Archives of Biochemistry and Biophysics , 页码:23-33 , 文章类型: Article,,卷期:2009年488-1]
- RIG-I, MIDA5 and LGP2 are cytosolic pattern recognition receptors detecting single-stranded or double-stranded RNA in virally infected cells. The activation of RIG-I or MDA5 stimulates the secretion of type I interferons...
- Induction of antioxidant and phase 2 drug-metabolizing enzymes by falcarindiol isolated from Notopterygium incisum extract, which activates the Nrf2/ARE pathway, leads to cytoprotection against oxidative and electrophilic stress
[作者:Ohnuma, T; Komatsu, T; Nakayama, S; Nishiyama, T; Ogura, K; Hiratsuka, A,期刊:Archives of Biochemistry and Biophysics , 页码:34-41 , 文章类型: Article,,卷期:2009年488-1]
- In the present study, we isolated falcarindiol from Notopterygium incisum and investigated the effect of falcarindiol on the expression of antioxidant enzymes (AOEs), such as catalase, and phase 2 drug-metabolizing enzym...
- Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) is indispensable for normal embryogenesis in zebrafish, Danio rerio
[作者:Sueyoshi, N; Nimura, T; Ishida, A; Taniguchi, T; Yoshimura, Y; Ito, M; Shigeri, Y; Kameshita, I,期刊:Archives of Biochemistry and Biophysics , 页码:48-59 , 文章类型: Article,,卷期:2009年488-1]
- Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP) dephosphorylates and regulates multifunctional Ca2+/calmodulin-dependent protein kinases (CaMKs). However, the biological functions of this enzyme have not bee...
- Carboplatin-induced alteration of the thiol homeostasis in the isolated perfused rat kidney
[作者:Giustarini, D; Dalle-Donne, I; Paccagnini, E; Milzani, A; Rossi, R,期刊:Archives of Biochemistry and Biophysics , 页码:83-89 , 文章类型: Article,,卷期:2009年488-1]
- Carboplatin elicits minor side effects with respect to its first generation analogue cisplatin. Nevertheless, a close-dependent nephrotoxicity of the drug has been reported to occur both in patients and in rats and a pos...
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