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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共28条记录   Cleaving Carbon-Carbon Bonds by the Release of Trifluoroacetate to Remodel Molecules and Assemble Fluorinated Structures [作者：HAN CHANGHO; KIM EUN HOO; COLBY DAVID A,期刊：SYNLETT, 页码：1559-1563 , 文章类型： Article，,卷期：2012年-11] Cleaving carbon-carbon bonds is a significant synthetic challenge. The release of trifluoroacetate presents a powerful force to break these strong bonds. Herein, a brief review of the role of the release of trifluoroacet... Process Research and Development for Heterocyclic p38 MAP Kinase Inhibitors [作者：THIEL OLIVER R; ACHMATOWICZ MICHAL; MILBURN ROBERT M,期刊：SYNLETT, 页码：1564-1574 , 文章类型： Article，,卷期：2012年-11] The need to access different heterocyclic cores as part of p38 MAP kinase inhibitors led to the discovery and development of several efficient approaches to three separate classes of heterocycles, namely phthalazines, py... Bio-inspired Chiral Primary Amine Catalysis [作者：ZHANG LONG; LUO SANZHONG,期刊：SYNLETT, 页码：1575-1589 , 文章类型： Article，,卷期：2012年-11] The search for new catalysts with superior performance and broad applicability remains a central theme in asymmetric organocatalysis. Inspired by Nature as well as by numerous previous efforts, we have developed chiral p... Conjugate Additions to Vinyl-Substituted Aromatic N-Heterocycles [作者：KLUMPP DOUGLAS A,期刊：SYNLETT, 页码：1590-1604 , 文章类型： Article，,卷期：2012年-11] Conjugate or Michael addition to vinyl-substituted aromatic N-heterocycles has been a useful synthetic method for the synthesis of functionalized heterocyclic compounds. A wide variety of heterocycles and nucleophiles un... Palladium-Catalyzed Direct 1,4-Addition of Heteroarenes to alpha,beta-Unsaturated Ketones via C-H Activation [作者：ZHANG XUAN; YU XIAOQIANG; FENG XIUJUAN; BAO MING,期刊：SYNLETT, 页码：1605-1608 , 文章类型： Article，,卷期：2012年-11] Palladium-catalyzed direct conjugate additions of heteroarenes to alpha,beta-unsaturated ketones via C-H activation are described. The reactions of heteroarenes with alpha,beta-unsaturated ketones proceeded smoothly in t... One-Pot Synthesis of beta-Keto Esters and Preparation of 3-Ketopalmitoyl-CoA [作者：KOSAK URBAN; KOVAC ANDREJA; GOBEC STANISLAV,期刊：SYNLETT, 页码：1609-1612 , 文章类型： Article，,卷期：2012年-11] beta-Keto esters were synthesized from acyl chlorides and sodium ethyl acetoacetate in EtOH using a simple 'one-pot, one-step' method. The deacetylation of alpha-acetyl beta-keto ester to beta-keto ester was performed si... Metal-Free Phosphorylations of 1,3,4-Oxadiazoles and Related Heterocycles [作者：ZOU LIANGHUA; DONG ZHIBING; BOLM CARSTEN,期刊：SYNLETT, 页码：1613-1616 , 文章类型： Article，,卷期：2012年-11] 1,3,4-Oxadiazoles have been phosphorylated at C5 in yields of >90% under mild metal-free reactions conditions using triethylamine as base. Other azoles undergo analogous phosphorylations albeit in lower yields. A Method for the Generation of Pam(2)Cys-Based Lipopeptide Mimics via CuAAC Click Chemistry [作者：YEUNG HO; LEE DONG JUN; WILLIAMS GEOFFREY M; HARRIS PAUL W R; DUNBAR ROD P; BRIMBLE MARGARET A,期刊：SYNLETT, 页码：1617-1620 , 文章类型： Article，,卷期：2012年-11] The immunostimulatory activity of naturally occurring lipopeptides as bacterial cell wall components arises due to the presence of certain lipid motifs. S-[2,3-bis(palmitoyloxy)propyl]cysteine (Pam(2)Cys) is a lipid moti... Direct C-H Arylation of Quinones with Anilines [作者：LAMBLIN MARC; NATURALE GUILLAUME; DESSOLIN JEAN; FELPIN FRANCOISXAVIER,期刊：SYNLETT, 页码：1621-1624 , 文章类型： Article，,卷期：2012年-11] We discovered that anilines were suitable for the direct C-H arylation of benzoquinone in the presence of tert-butyl nitrite. This new reaction proceeds through the in situ formation of a diazonium hydroxide species. The... An Enantioselective Mukaiyama Aldol Reaction as the Key Step towards the Tetrahydropyran Core of Psymberin via a gamma-Butyrolactone Intermediate [作者：BIELITZA MAX; PIETRUSZKA JOERG,期刊：SYNLETT, 页码：1625-1628 , 文章类型： Article，,卷期：2012年-11] We report an alternative synthetic route towards the tetrahydropyran core of psymberin. The key steps are a catalytic enantioselective Mukaiyama aldol reaction and a syn reduction, which allowed for the rapid assembly of... Catalytic Enantioselective Friedel-Crafts Alkylation of Indoles with Fumarate Derivatives in the Presence of Chiral Palladium Complexes [作者：LEE HYUN JOO; KIM DAE YOUNG,期刊：SYNLETT, 页码：1629-1632 , 文章类型： Article，,卷期：2012年-11] The catalytic enantioselective Friedel-Crafts alkylation reaction promoted by chiral palladium complexes is described. The treatment of indoles with fumarate derivatives under the mild reaction conditions afforded the co... An Efficient Method for the Synthesis of Symmetrical Disiloxanes from Alkoxysilanes Using Meerwein's Reagent [作者：JORAPUR YOGESH R; SHIMADA TOYOSHI,期刊：SYNLETT, 页码：1633-1638 , 文章类型： Article，,卷期：2012年-11] We report here a new and efficient route to symmetrical disiloxanes from their corresponding alkoxysilanes using Meerwein's reagent as mediator and potassium carbonate as additive under mild reaction conditions in aceton... Synthesis of 4-Quinolones through Nickel-Catalyzed Intramolecular Amination on the beta-Carbon of o-(N-Alkylamino)propiophenones [作者：UENO SATOSHI; SHIMIZU RYOSUKE; MAEDA RYOHEI; KUWANO RYOICHI,期刊：SYNLETT, 页码：1639-1642 , 文章类型： Article，,卷期：2012年-11] o-(N-Alkylamino)propiophenones are converted into 4-quinolones in the presence of chlorobenzene, potassium phosphate, morpholine, and nickel(0) catalyst. The reaction proceeds through the nickel-catalyzed formation of be... DDQ-Promoted C-S Bond Formation: Synthesis of 2-Aminobenzothiazole Derivatives under Transition-Metal-, Ligand-, and Base-Free Conditions [作者：WANG RUI; YANG WENJUAN; YUE LIANG; PAN WEI; ZENG HONGYAO,期刊：SYNLETT, 页码：1643-1648 , 文章类型： Article，,卷期：2012年-11] A transition-metal-free method for the intramolecular S-arylation of o-halobenzothiaoureas via DDQ-mediated leading to the 2-aminobenzothiazole derivatives is reported. The reactions are performed at room temperature und... Rhodium(III)-Catalyzed Oxidative Olefination of N-(Naphthalen-1-yl)amides [作者：WANG XIAOWEI; LI XUTING; XIAO JIAN; JIANG YI; LI XINGWEI,期刊：SYNLETT, 页码：1649-1652 , 文章类型： Article，,卷期：2012年-11] Rhodium(III)-catalyzed oxidative coupling of N-(naphthalen-1-yl)amides with acrylates and styrene was achieved through selective C-H bond activation at the peri position. This reaction proceeded smoothly to give the dire... K2CO3/NaI-Induced Cyclization of omega-Bromo alpha-Cyano Ketones: A New Annulation Approach for the Formation of Carbalkoxycyclohexane Ring System [作者：TU CHEHAO; SHIA KAKSHAN; KUO SHENGCHU; LIU HSINGJANG; HSIEH MINTSANG,期刊：SYNLETT, 页码：1653-1656 , 文章类型： Article，,卷期：2012年-11] An operationally simple and highly effective annulation process, making use of ZnCl2-catalyzed Michael addition and K2CO3/NaI-induced cyclization as key manipulations, has been developed to construct various bicyclic sys...