- Merkel cell polyomavirus sequences are frequently detected in nonmelanoma skin cancer of immunosuppressed patients
[作者:Kassem, A; Technau, K; Kurz, AK; Pantulu, D; Loning, M; Kayser, G; Stickeler, E; Weyers, W; Diaz, C; Werner, M; Nashan, D; Hausen, AZ,期刊:International Journal of Cancer, 页码:356-361 , 文章类型: Article,,卷期:2009年125-2]
- Recently, a new human polyoma virus has been identified in Merkel cell carcinomas (MCC). MCC is a highly aggressive neuroendocrine nonmelanoma skin cancer (NMSC) associated with immunosuppression. Clonal integration of t...
- Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: An epidemic of viral-induced carcinoma?
[作者:Nasman, A; Attner, P; Hammarstedt, L; Do, J; Eriksson, M; Giraud, G; Ahrlund-Richter, S; Marklund, L; Romanitan, M; Lindquist, D; Ramqvist, T; Lindholm, J; Sparen, P; Ye, WM; Dahistrand, H; Munck-Wikland, E; Dalianis, T,期刊:International Journal of Cancer, 页码:362-366 , 文章类型: Article,,卷期:2009年125-2]
- In the county of Stockholm, between 1970 and 2002, we have previously reported a 3-fold parallel increase in the incidence of tonsillar squamous cell carcinoma (SCC) and the proportion of human papillomavirus (HPV) posit...
- Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages
[作者:Duluc, D; Corvaisier, M; Blanchard, S; Catala, L; Descamps, P; Gamelin, E; Ponsoda, S; Delneste, Y; Hebbar, M; Jeannin, P,期刊:International Journal of Cancer, 页码:367-373 , 文章类型: Article,,卷期:2009年125-2]
- Tumor-associated macrophages (TAM) are M2d-polarized cells (IL-10(high), IL-12(low), ILT3(high), CD86(low)) that accumulate in tumor microenvironment. TAM inhibit antitumor T lymphocyte generation and function, contribut...
- Increased frequency of nonconventional double positive CD4CD8 alpha beta T cells in human breast pleural effusions
[作者:Desfrancois, J; Derre, L; Corvaisier, M; Le Mevel, B; Catros, V; Jotereau, F; Gervois, N,期刊:International Journal of Cancer, 页码:374-380 , 文章类型: Article,,卷期:2009年125-2]
- Breast cancer remains a leading cause of cancer-related death within the female population. Immunotherapy is expected to provide additional therapeutic benefits but has met so far limited success. This may be due in part...
- Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma
[作者:Moribe, T; Iizuka, N; Miura, T; Kimura, N; Tamatsukuri, S; Ishitsuka, H; Hamamoto, Y; Sakamoto, K; Tamesa, T; Oka, M,期刊:International Journal of Cancer, 页码:388-397 , 文章类型: Article,,卷期:2009年125-2]
- The current study was conducted to identify robust methylation markers and their combinations that may prove useful for the diagnosis of early hepatocellular carcinoma (HCC). To achieve this, we performed in silico CpG m...
- Population-based study of autoimmune conditions and the risk of specific lymphoid malignancies
[作者:Anderson, LA; Gadalla, S; Morton, LM; Landgren, O; Pfeiffer, R; Warren, JL; Berndt, SI; Ricker, W; Parsons, R; Engels, EA,期刊:International Journal of Cancer, 页码:398-405 , 文章类型: Article,,卷期:2009年125-2]
- Some autoimmune conditions are associated with increased risk of lympboid malignancies, but information on specific malignancy subtypes is limited. From the U.S. Surveillance Epidemiology and End Results-Medicare databas...
- Lifetime and baseline alcohol intake and risk of cancer of the upper aero-digestive tract in the European prospective investigation into cancer and nutrition (EPIC) study
[作者:Weikert, C; Dietrich, T; Boeing, H; Bergmann, MM; Boutron-Ruault, MC; Clavel-Chapelon, F; Allen, N; Key, T; Lund, E; Olsen, A; Tjonneland, A; Overvad, K; Rohrmann, S; Linseisen, J; Pischon, T; Trichopoulou, A; Weinehall, L; Johansson, I; Sanchez, MJ; Agudo, A; Barricarte, A; Amiano, P; Chirlaque, MD; Quiros, JR; Wirfalt, E; Peeters, PH; Bueno-de-Mesquita, HB; Vrieling, A; Pala, V; Palli, D; Vineis, P; Tumino, R; Panico, S; Bingham, S; Khaw, KT; Norat, T; Jenab, M; Ferrari, P; Slimani, N; Riboli, E,期刊:International Journal of Cancer, 页码:406-412 , 文章类型: Article,,卷期:2009年125-2]
- Recent alcohol consumption is all established risk factor for squamous cell carcinoma (SCC) or the upper aero-digestive tract. In contrast, the role or lifetime exposure to alcohol with regard to risk of SCC is not well ...
- Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood
[作者:Khamly, KK; Thursfield, VJ; Fay, M; Desai, J; Toner, GC; Choong, PFM; Ngan, SYK; Powell, GJ; Thomas, DM,期刊:International Journal of Cancer, 页码:426-431 , 文章类型: Article,,卷期:2009年125-2]
- Good evidence indicates that adolescents and young adults (AYAs) with cancer do badly compared with children with similar cancers. The reasons are poorly understood. Australian registry data on 14,824 cancers of adolesce...
- A new pulsed electric field therapy for melanoma disrupts the tumor's blood supply and causes complete remission without recurrence
[作者:Nuccitelli, R; Chen, X; Pakhomov, AG; Baldwin, WH; Sheikh, S; Pomicter, JL; Ren, W; Osgood, C; Swanson, RJ; Kolb, JF; Beebe, SJ; Schoenbach, KH,期刊:International Journal of Cancer, 页码:438-445 , 文章类型: Article,,卷期:2009年125-2]
- We have discovered a new, ultrafast therapy for treating skin cancer that is extremely effective with a total electric field exposure time of only 180 mu sec. The application of 300 high-voltage (40 kV/cm), ultrashort (3...
- Double stranded-RNA-mediated activation of P21 gene induced apoptosis and cell cycle arrest in renal cell carcinoma
[作者:Whitson, JM; Noonan, EJ; Pookot, D; Place, RF; Dahiya, R,期刊:International Journal of Cancer, 页码:446-452 , 文章类型: Article,,卷期:2009年125-2]
- Small double stranded RNAs (dsRNA) are a new class of molecules which regulate gene expression. Accumulating data suggest that some dsRNA can function as tumor suppressors. Here, we report further evidence on the potenti...
- Histone deacetylase inhibitors suppress thymidylate synthase gene expression and synergize with the fluoropyrimidines in colon cancer cells
[作者:Fazzone, W; Wilson, PM; LaBonte, MJ; Lenz, HJ; Ladner, RD,期刊:International Journal of Cancer, 页码:463-473 , 文章类型: Article,,卷期:2009年125-2]
- Despite recent therapeutic advances, the response rates to chemotherapy for patients with metastatic colon cancer remain at similar to 50% with the fluoropyrimidine, 5-fluorouracil (5-FU), continuing to serve as the foun...
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