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  • HIF-1 alpha and HIF-2 alpha have divergent roles in colon cancer
    [作者:Imamura, T; Kikuchi, H; Herraiz, MT; Park, DY; Mizukami, Y; Mino-Kenduson, M; Lynch, MP; Rueda, BR; Benita, Y; Xavier, RJ; Chung, DC,期刊:International Journal of Cancer, 页码:763-771 , 文章类型: Article,,卷期:2009年124-4]
  • Hypoxia-inducible factor (HIF)-1 and HIF-2 are heterodimeric transcription factors that mediate the cellular response to hypoxia. Their key regulatory subunits, HIF-1 alpha and HIF-2 alpha are induced similarly by hypoxi...