Irritable bowel syndrome (IBS) is a chronic, highly prevalent gastrointestinal motility disorder characterized by abdominal discomfort/pain associated with altered bowel habits such as diarrhea or constipation or both...
Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI), although its norepinephrine reuptake inhibition predominates. It has been marketed in Europe and Japan as an antidepressant for many years, but only...
A new agent containing a combination of dextromethorphan (DM) and quinidine (Q) is currently under development for the treatment of pseudobulbar affect (PBA). PBA is a disorder of emotional regulation, characterized b...
Pemetrexed disodium is a multitargeted antifolate cytotoxic chemotherapy agent approved by the U.S. Food and Drug Administration (FDA) initially for the treatment of malignant pleural mesothelioma, and in August 2004 ...
Endocrine therapy is often the preferred treatment option for postmenopausal women with hormone receptor-positive breast cancer. However, as many patients eventually develop resistance there is a need for novel, effic...
Coronary heart disease (CHD) is one of the leading causes of morbidity and mortality worldwide and modification of established cardiovascular risk factors has become increasingly important in order to minimize the imp...
Treating acute and chronic musculoskeletal pain is essential for improving healing of traumatic injuries and surgical procedures, and for improving patient quality of life. Physicians are limited primarily to treating...
Candidemia is a growing problem in tertiary care hospitals all over the world. It is generally difficult to diagnose, leads to prolonged hospitalization, has a mortality rate of around 50% and is a financial burden to...