- Dephosphorylation of the Core Clock Protein KaiC in the Cyanobacterial KaiABC Circadian Oscillator Proceeds via an ATP Synthase Mechanism
[作者:Egli, M; Mori, T; Pattanayek, R; Xu, Y; Qin, XM; Johnson, CH,期刊:Biochemistry, 页码:1547-1558 , 文章类型: Article,,卷期:2012年51-8]
- The circadian clock of the cyanobacterium Synechococcus elongatus can be reconstituted in vitro from three proteins, KaiA, KaiB, and KaiC in the presence of ATP, to tick in a temperature-compensated manner. KaiC, the cen...
- Role of Calcium in Metalloenzymes: Effects of Calcium Removal on the Axial Ligation Geometry and Magnetic Properties of the Catalytic Diheme Center in MauG
[作者:Chen, Y; Naik, SG; Krzystek, J; Shin, S; Nelson, WH; Xue, SH; Yang, JJ; Davidson, VL; Liu, AM,期刊:Biochemistry, 页码:1586-1597 , 文章类型: Article,,卷期:2012年51-8]
- MauG is a diheme enzyme possessing a five-coordinate high-spin heme with an axial His ligand and a six-coordinate low-spin heme with His-Tyr axial ligation. A Ca2+ ion is linked to the two hemes via hydrogen bond network...
- Proline 107 Is a Major Determinant in Maintaining the Structure of the Distal Pocket and Reactivity of the High-Spin Heme of MauG
[作者:Feng, ML; Jensen, LMR; Yukl, ET; Wei, XX; Liu, AM; Wilmot, CM; Davidson, VL,期刊:Biochemistry, 页码:1598-1606 , 文章类型: Article,,卷期:2012年51-8]
- The diheme enzyme MauG catalyzes a six-electron oxidation required for posttranslational modification of a precursor of methylamine dehydrogenase (preMADH) to complete the biosynthesis of its protein-derived tryptophan t...
- O-2-Evolving Chlorite Dismutase as a Tool for Studying O-2-Utilizing Enzymes
[作者:Dassama, LMK; Yosca, TH; Conner, DA; Lee, MH; Blanc, B; Streit, BR; Green, MT; DuBois, JL; Krebs, C; Bollinger, JM,期刊:Biochemistry, 页码:1607-1616 , 文章类型: Article,,卷期:2012年51-8]
- The direct interrogation of fleeting intermediates by rapid-mixing kinetic methods has significantly advanced our understanding of enzymes that utilize dioxygen. The gas's modest aqueous solubility (<2 mM at 1 atm) prese...
- Imaging of Protein Crystals with Two-Photon Microscopy
[作者:Padayatti, P; Palczewska, G; Sun, WY; Palczewski, K; Salom, D,期刊:Biochemistry, 页码:1625-1637 , 文章类型: Article,,卷期:2012年51-8]
- Second-order nonlinear optical imaging of chiral crystals (SONICC), which portrays second-harmonic generation (SHG) by noncentrosymmetric crystals, is emerging as a powerful imaging technique for protein crystals in medi...
- Two Translation Products of Yersinia yscQ Assemble To Form a Complex Essential to Type III Secretion
[作者:Bzymek, KP; Hamaoka, BY; Ghosh, P,期刊:Biochemistry, 页码:1669-1677 , 文章类型: Article,,卷期:2012年51-8]
- The bacterial flagellar C-ring is composed of two essential proteins, FliM and FliN. The smaller protein, FliN, is similar to the C-terminus of the larger protein, FliM, both being composed of SpoA domains. While bacteri...
- Conserved Signal Peptide Recognition Systems across the Prokaryotic Domains
[作者:Coulthurst, SJ; Dawson, A; Hunter, WN; Sargent, F,期刊:Biochemistry, 页码:1678-1686 , 文章类型: Article,,卷期:2012年51-8]
- The twin-arginine translocation (Tat) pathway is a protein targeting system found in bacteria, archaea, and chloroplasts. Proteins are directed to the Tat translocase by N-terminal signal peptides containing SRRxFLK "twi...
- Human Glutaredoxin 3 Forms [2Fe-2S]-Bridged Complexes with Human BolA2
[作者:Li, HR; Mapolelo, DT; Randeniya, S; Johnson, MK; Outten, CE,期刊:Biochemistry, 页码:1687-1696 , 文章类型: Article,,卷期:2012年51-8]
- Human glutaredoxin 3 (Glrx3) is an essential [2Fe-2S]-binding protein with ill-defined roles in immune cell response, embryogenesis, cancer cell growth, and regulation of cardiac hypertrophy. Similar to other members of ...
- Rapid Exchange of Metal between Zn-7-Metallothionein-3 and Amyloid-beta Peptide Promotes Amyloid-Related Structural Changes
[作者:Pedersen, JT; Hureau, C; Hemmingsen, L; Heegaard, NHH; Ostergaard, J; Vasak, M; Faller, P,期刊:Biochemistry, 页码:1697-1706 , 文章类型: Article,,卷期:2012年51-8]
- Metal ions, especially Zn2+ and Cu2+, are implemented in the neuropathogenesis of Alzheimer's disease (AD) by modulating the aggregation of amyloid-beta peptides (A beta). Also, Cu2+ may promote AD) neurotoxicity through...
|