- Keratan sulfate suppresses cartilage damage and ameliorates inflammation in an experimental mice arthritis model
[作者:Hayashi, M; Kadomatsu, K; Ishiguro, N,期刊:Biochemical and Biophysical Research Communications, 页码:463-468 , 文章类型: Article,,卷期:2010年401-3]
- Proteoglycans bearing keratan sulfate (KS), such as aggrecan, are components of the human cartilage extracellular matrix (ECM). However, the role of KS in influencing cartilage degradation associated with arthritis remai...
- Chemical inhibition of sulfation accelerates neural differentiation of mouse embryonic stem cells and human induced pluripotent stem cells
[作者:Sasaki, N; Hirano, T; Kobayashi, K; Toyoda, M; Miyakawa, Y; Okita, H; Kiyokawa, N; Akutsu, H; Umezawa, A; Nishihara, S,期刊:Biochemical and Biophysical Research Communications, 页码:480-486 , 文章类型: Article,,卷期:2010年401-3]
- Pluripotency of embryonic stem cells (ESCs) is maintained by the balancing of several signaling pathways, such as Wnt, BMP, and FGF, and differentiation of ESCs into a specific lineage is induced by the disruption of thi...
- A functional interaction between CPI-17 and RACK1 proteins in bronchial smooth muscle cells
[作者:Chiba, Y; Tanabe, M; Sakai, H; Kimura, S; Misawa, M,期刊:Biochemical and Biophysical Research Communications, 页码:487-490 , 文章类型: Article,,卷期:2010年401-3]
- CPI-17 is a phosphorylation-dependent inhibitor of smooth muscle myosin light chain. Using yeast two-hybrid system, we have identified the receptor for activated C kinase 1 (RACK1) as a novel interaction partner of CPI-1...
- Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors
[作者:Choi, J; Jang, H; Kim, H; Kim, ST; Cho, EJ; Youn, HD,期刊:Biochemical and Biophysical Research Communications, 页码:327-332 , 文章类型: Article,,卷期:2010年401-3]
- During myogenesis, transcriptional activities of two major myogenic factors, MyoD and myocyte enhancer factor 2 (Mef2) are regulated by histone modifications that switch on and off the target genes. However, the transiti...
- Comparative study of the chondrogenic potential of human bone marrow stromal cells, neonatal chondrocytes and adult chondrocytes
[作者:Saha, S; Kirkham, J; Wood, D; Curran, S; Yang, XB,期刊:Biochemical and Biophysical Research Communications, 页码:333-338 , 文章类型: Article,,卷期:2010年401-3]
- Cartilage tissue engineering is still a major clinical challenge with optimisation of a suitable source of cells for cartilage repair/regeneration not yet fully addressed. The aims of this study were to compare and contr...
- ERK1/2 is involved in cyclic compressive force-induced IL-6 secretion in MLO-Y4 cells
[作者:Chen, WC; Ma, YY; Ye, H; He, Y; Li, XY; Li, JH; Zhu, ZM; Wang, H,期刊:Biochemical and Biophysical Research Communications, 页码:339-343 , 文章类型: Article,,卷期:2010年401-3]
- We previously reported that cyclic compressive force (CCF) induced interleukin-6 mRNA expression in osteocyte-like MLO-Y4 cells. But little is known about how the stimuli are converted into the biochemical signals in MLO...
- Cyclic stretch-induced stress fiber dynamics - Dependence on strain rate, Rho-kinase and MLCK
[作者:Lee, CF; Haase, C; Deguchi, S; Kaunas, R,期刊:Biochemical and Biophysical Research Communications, 页码:344-349 , 文章类型: Article,,卷期:2010年401-3]
- Stress fiber realignment is an important adaptive response to cyclic stretch for nonmuscle cells, but the mechanism by which such reorganization occurs is not known. By analyzing stress fiber dynamics using live cell mic...
- CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells
[作者:Kajihara, R; Fukushige, S; Shioda, N; Tanabe, K; Fukunaga, K; Inui, S,期刊:Biochemical and Biophysical Research Communications, 页码:350-355 , 文章类型: Article,,卷期:2010年401-3]
- Protein phosphatase (PP) 6 is a serine threonine phosphatase which belongs to the PP2A subfamily of protein phosphatases. PP6 has been implicated in the control of apoptosis. A dominant negative form PP6 (DN-PP6) mutant ...
- ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma
[作者:Ungerer, C; Doberstein, K; Burger, C; Hardt, K; Boehncke, WH; Bohm, B; Pfeilschifter, J; Dummer, R; Mihic-Probst, D; Gutwein, P,期刊:Biochemical and Biophysical Research Communications, 页码:363-369 , 文章类型: Article,,卷期:2010年401-3]
- In a mouse melanoma metastasis model it has been recently shown that ADAM] 5 overexpression in melanoma cells significantly reduced the number of metastatic nodules on the lung. Unfortunately, the expression of ADAM15 in...
- Prediction of midbody, centrosome and kinetochore proteins based on gene ontology information
[作者:Chen, W; Lin, H,期刊:Biochemical and Biophysical Research Communications, 页码:382-384 , 文章类型: Article,,卷期:2010年401-3]
- In the process of cell division, a great deal of proteins is assembled into three distinct organelles, namely midbody, centrosome and kinetochore. Knowing the localization of microkit (midbody, centrosome and kinetochore...
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