- Arg206 of SNAP-25 is essential for neuroexocytosis at the Drosophila melanogaster neuromuscular junction
[作者:Megighian, A; Scorzeto, M; Zanini, D; Pantano, S; Rigoni, M; Benna, C; Rossetto, O; Montecucco, C; Zordan, M,期刊:Journal of cell science, 页码:3276-3283 , 文章类型: Article,,卷期:2010年123-19]
- An analysis of SNAP-25 isoform sequences indicates that there is a highly conserved arginine residue (198 in vertebrates, 206 in the genus Drosophila) within the C-terminal region, which is cleaved by botulinum neurotoxi...
- Regulation of bile canalicular network formation and maintenance by AMP-activated protein kinase and LKB1
[作者:Fu, D; Wakabayashi, Y; Ido, Y; Lippincott-Schwartz, J; Arias, IM,期刊:Journal of cell science, 页码:3294-3302 , 文章类型: Article,,卷期:2010年123-19]
- AMP-activated protein kinase (AMPK), a cellular metabolic sensor, is essential in energy regulation and metabolism. Hepatocyte polarization during liver development and regeneration parallels increased metabolism. The cu...
- The nonsense-mediated decay pathway maintains synapse architecture and synaptic vesicle cycle efficacy
[作者:Long, AA; Mahapatra, CT; Woodruff, EA; Rohrbough, J; Leung, HT; Shino, S; An, LL; Doerge, RW; Metzstein, MM; Pak, WL; Broadie, K,期刊:Journal of cell science, 页码:3303-3315 , 文章类型: Article,,卷期:2010年123-19]
- A systematic Drosophila forward genetic screen for photoreceptor synaptic transmission mutants identified no-on-and-no-off transient C (nonC) based on loss of retinal synaptic responses to light stimulation. The cloned g...
- PKC zeta regulates cell polarisation and proliferation restriction during mammary acinus formation
[作者:Whyte, J; Thornton, L; McNally, S; McCarthy, S; Lanigan, F; Gallagher, WM; Stein, T; Martin, F,期刊:Journal of cell science, 页码:3316-3328 , 文章类型: Article,,卷期:2010年123-19]
- Mammary epithelial cells organize in three dimensions and generate acini when supported on laminin-rich extracellular matrix. Acinus formation begins with the apicobasal polarisation of the outer cells of the assembly an...
- Transmembrane domains control exclusion of membrane proteins from clathrin-coated pits
[作者:Mercanti, V; Marchetti, A; Lelong, E; Perez, F; Orci, L; Cosson, P,期刊:Journal of cell science, 页码:3329-3335 , 文章类型: Article,,卷期:2010年123-19]
- Efficient sorting of proteins is essential to allow transport between intracellular compartments while maintaining their specific composition. During endocytosis, membrane proteins can be concentrated in endocytic vesicl...
- Pro-cathepsin D interacts with the extracellular domain of the beta chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth
[作者:Beaujouin, M; Prebois, C; Derocq, D; Laurent-Matha, V; Masson, O; Pattingre, S; Coopman, P; Bettache, N; Grossfield, J; Hollingsworth, RE; Zhang, HY; Yao, ZM; Hyman, BT; van der Geer, P; Smith, GK; Liaudet-Coopman, E,期刊:Journal of cell science, 页码:3336-3346 , 文章类型: Article,,卷期:2010年123-19]
- Interactions between cancer cells and fibroblasts are crucial in cancer progression. We have previously shown that the aspartic protease cathepsin D (cath-D), a marker of poor prognosis in breast cancer that is overexpre...
- Decrease of sialic acid residues as an eat-me signal on the surface of apoptotic lymphocytes
[作者:Meesmann, HM; Fehr, EM; Kierschke, S; Herrmann, M; Bilyy, R; Heyder, P; Blank, N; Krienke, S; Lorenz, HM; Schiller, M,期刊:Journal of cell science, 页码:3347-3356 , 文章类型: Article,,卷期:2010年123-19]
- The silent clearance of apoptotic cells is essential for cellular homeostasis in multicellular organisms, and several mediators of apoptotic cell recognition have been identified. However, the distinct mechanisms involve...
- WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
[作者:Coombs, GS; Yu, J; Canning, CA; Veltri, CA; Covey, TM; Cheong, JK; Utomo, V; Banerjee, N; Zhang, ZH; Jadulco, RC; Concepcion, GP; Bugni, TS; Harper, MK; Mihalek, I; Jones, CM; Ireland, CM; Virshup, DM,期刊:Journal of cell science, 页码:3357-3367 , 文章类型: Article,,卷期:2010年123-19]
- Wnt proteins are secreted post-translationally modified proteins that signal locally to regulate development and proliferation. The production of bioactive Wnts requires a number of dedicated factors in the secreting cel...
- Src-dependent phosphorylation of ROCK participates in regulation of focal adhesion dynamics
[作者:Lee, HH; Tien, SC; Jou, TS; Chang, YC; Jhong, JG; Chang, ZF,期刊:Journal of cell science, 页码:3368-3377 , 文章类型: Article,,卷期:2010年123-19]
- When a cell migrates, the RhoA-ROCK-mediated contractile signal is suppressed in the leading edge to allow dynamic adhesions for protrusion. However, several studies have reported that RhoA is indeed active in the leadin...
- PEX11 family members are membrane elongation factors that coordinate peroxisome proliferation and maintenance
[作者:Koch, J; Pranjic, K; Huber, A; Ellinger, A; Hartig, A; Kragler, F; Brocard, C,期刊:Journal of cell science, 页码:3389-3400 , 文章类型: Article,,卷期:2010年123-19]
- Dynamic changes of membrane structure are intrinsic to organelle morphogenesis and homeostasis. Ectopic expression of proteins of the PEX11 family from yeast, plant or human lead to the formation of juxtaposed elongated ...
- Developmental regulation and extracellular release of a VSG expression-site-associated gene product from Trypanosoma brucei bloodstream forms
[作者:Barnwell, EM; van Deursen, FJ; Jeacock, L; Smith, KA; Maizels, RM; Acosta-Serrano, A; Matthews, K,期刊:Journal of cell science, 页码:3401-3411 , 文章类型: Article,,卷期:2010年123-19]
- Trypanosomes evade host immunity by exchanging variant surface glycoprotein (VSG) coats. VSG genes are transcribed from telomeric expression sites, which contain a diverse family of expression-site-associated genes (ESAG...
- Protein mobilities and P-selectin storage in Weibel-Palade bodies (vol 123, pg 2964, 2010)
[作者:Kiskin, NI; Hellen, N; Babich, V; Hewlett, L; Knipe, L; Hannah, MJ; Carter, T,期刊:Journal of cell science, 页码:3412-3412 , 文章类型: Correction,,卷期:2010年123-19]
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- ERK5 is required for VEGF-mediated survival and tubular morphogenesis of primary human microvascular endothelial cells (vol 123, pg 3189, 2010)
[作者:Roberts, OL; Holmes, K; Muller, J; Cross, DAE; Cross, MJ,期刊:Journal of cell science, 页码:3413-3413 , 文章类型: Correction,,卷期:2010年123-19]
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