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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共42条记录   Synthesis and Antisense Properties of Fluoro Cyclohexenyl Nucleic Acid (F-CeNA), a Nuclease Stable Mimic of 2 '-Fluoro RNA [作者：SETH PUNIT P; YU JINGHUA; JAZAYERI ALI; PALLAN PRADEEP S; ALLERSON CHARLES R; OSTERGAARD MICHAEL E; LIU FENGWU; HERDEWIJN PIET; EGLI MARTIN; SWAYZE ERIC E,期刊：Journal of Organic Chemistry, 页码：5074-5085 , 文章类型： Article，,卷期：2012年77-11] We report the design and synthesis of 2'-fluoro cyclohexenyl nucleic acid (F-CeNA) pyrimidine phosphoramidites and the synthesis and biophysical, structural, and biological evaluation of modified oligonucleotides. The sy... Design, Synthesis, and Biological Activities of Some Branched Carbasugars: Construction of a Substituted 6-Oxabicyclo[3.2.1]nonane Skeleton [作者：BARAN ARIF; CAMBUL SINEM; NEBIOGLU MEHMET; BALCI METIN,期刊：Journal of Organic Chemistry, 页码：5086-5097 , 文章类型： Article，,卷期：2012年77-11] Transformation of c-yclohexa-2,4-diene-1,2-diylbis(methylene) diacetate to various carbasugars is described. Photooxygenation of a cyclohexadiene derivative gave a bicyclic endoperoxide, which was reduced with thiourea t... Stereoselective Total Synthesis of Nemorosone [作者：UWAMORI MASAHIRO; SAITO AYA; NAKADA MASAHISA,期刊：Journal of Organic Chemistry, 页码：5098-5107 , 文章类型： Article，,卷期：2012年77-11] The highly stereoselective total synthesis of nemorosone via a new approach to the bic-yclo[3.3.1]nonane-2,4,9-trione core which features intramolecular cyclopropanation of an alpha-diazo ketone, stereoselective alkylati... Palladium-Catalyzed Approach for the General Synthesis of (E)-2-Arylmethylidene-N-tosylindolines and (E)-2-Arylmethylidene-N-tosyl/nosyltetrahydroquinolines: Access to 2-Substituted Indoles and Quinolines [作者：CHOWDHURY CHINMAY; DAS BIMOLENDU; MUKHERJEE SANJUKTA; ACHARI BASUDEB,期刊：Journal of Organic Chemistry, 页码：5108-5119 , 文章类型： Article，,卷期：2012年77-11] A facile and efficient method for the synthesis of (E)-2-arylmethylidene-N-tosylindolines and (E)-2-arylmethylidene-N-tosyl/nosyltetrahydroquinoline variants has been developed through palladium-catalyzed cyclocondensati... Extending Limits of Chlorine Kinetic Isotope Effects [作者：SWIDEREK KATARZYNA; PANETH PIOTR,期刊：Journal of Organic Chemistry, 页码：5120-5124 , 文章类型： Article，,卷期：2012年77-11] Chlorine kinetic isotope effects exceeding semiclassical limits were observed in enzyme-catalyzed reactions, but their source has not been yet identified. Herein we show that unusually large chlorine kinetic isotope effe... A Dieckmann Cyclization Route to Piperazine-2,5-diones [作者：ABOUSSAFY CLAUDE LARRIVEE; CLIVE DERRICK L J,期刊：Journal of Organic Chemistry, 页码：5125-5131 , 文章类型： Article，,卷期：2012年77-11] Piperazine-2,5-diones are formed by Dieckmann cyclization (NaH, THF) of substructures of the type CH2-N(R)C(O)CH2N-(R')CO2Ph in which the terminal methylene (CH2) that is adjacent to nitrogen closes onto the carbonyl gro... Fluoride-Mediated Elimination of Allyl Sulfones: Application to the Synthesis of a 2,4-Dimethyl-A-ring Vitamin D-3 Analogue [作者：SIKERVAR VIKAS; FLEET JAMES C; FUCHS PHILIP L,期刊：Journal of Organic Chemistry, 页码：5132-5138 , 文章类型： Article，,卷期：2012年77-11] A coupling strategy for the synthesis of 2,4-dimethyl-1 alpha,25(OH)(2)D-3 is achieved which involves methylation of a pro-A ring vinyl sulfone and in situ traping of the allyl sulfonyl anion with a CD ring allyl chlorid... Development of Catalysts for the Stereoselective Hydrogenation of alpha,beta-Unsaturated Ketones [作者：MAURER FRAUKE; HUCH VOLKER; ULLRICH ANGELIKA; KAZMAIER ULI,期刊：Journal of Organic Chemistry, 页码：5139-5143 , 文章类型： Article，,卷期：2012年77-11] Iridium phosphinitoxazoline complexes were found to be new efficient catalysts for the asymmetric hydrogenation of arylated alpha,beta-unsaturated ketones. Linear as well as cyclic substrates are hydrogenated with simila... Synthesis of alpha-Hydroxyacetophenones [作者：MCLAUGHLIN MARK; BELYK KEVIN M; QIAN GANG; REAMER ROBERT A; CHEN CHENGYI,期刊：Journal of Organic Chemistry, 页码：5144-5148 , 文章类型： Article，,卷期：2012年77-11] A general method for the preparation of alpha-hydroxyacetophenones is presented. Functionalized arylmagnesium species are transmetalated to the corresponding arylzinc intermediates, which undergo Cu(I)-catalyzed reaction... Synthesis of Symmetric 1,4-Diamino-2-Butynes via a Cu(I)-Catalyzed One-Pot A(3)-Coupling/Decarboxylative Coupling of a Propiolic Acid, an Aldehyde, and an Amine [作者：FENG HUANGDI; ERMOLATEV DENIS S; SONG GONGHUA; VAN DER EYCKEN ERIK V,期刊：Journal of Organic Chemistry, 页码：5149-5154 , 文章类型： Article，,卷期：2012年77-11] A novel microwave-assisted approach for the one-pot Cu(I)-catalyzed A(3)-coupling/decarboxylative coupling (PA(2)-coupling) of a propiolic acid, an aldehyde, and an amine, resulting in the formation of diversely substitu... Cucurbituril Adamantanediazirine Complexes and Consequential Carbene Chemistry [作者：GUPTA SHIPRA; CHOUDHURY RAJIB; KROIS DANIEL; BRINKER UDO H; RAMAMURTHY V,期刊：Journal of Organic Chemistry, 页码：5155-5160 , 文章类型： Article，,卷期：2012年77-11] Adamantanediazirines, precursors of adamantanylidenes, form 1:1 complexes (guest to host) with cucurbit[7]uril and cucurbit[8]uril and a 3:1 complex with a Pd nanocage in water. H-1 NMR spectra suggested that these compl... Total Synthesis of Thelephantin O, Vialinin A/Terrestrin A, and Terrestrins B-D [作者：FUJIWARA KENSHU; SATO TAKUTO; SANO YUSUKE; NORIKURA TOSHIO; KATOONO RYO; SUZUKI TAKANORI; MATSUE HAJIME,期刊：Journal of Organic Chemistry, 页码：5161-5166 , 文章类型： Article，,卷期：2012年77-11] The first total synthesis of natural, unsymmetrical 2',3'-diacyloxy-p-terphenyls, thelephantin O (1) and terrestrins C and D (2 and 3, respectively), was achieved via a practical route which was also applicable to the sy... Dibenzo[c,h][1,5]naphthyridinediones as Topoisomerase I Inhibitors: Design, Synthesis, and Biological Evaluation [作者：KISELEV EVGENY; EMPEY NICHOLAS; AGAMA KELI; POMMIER YVES; CUSHMAN MARK,期刊：Journal of Organic Chemistry, 页码：5167-5172 , 文章类型： Article，,卷期：2012年77-11] Dibenzo[c,h][1,5]naphthyridinediones were prepared via a novel synthetic pathway. The compounds were designed as topoisomerase I (Top 1) inhibitors based on the indenoisoquinoline series of drugs. The results of biologic... Synthesis of Acridines and Persubstituted Phenols from Cyclobutenones and Active Methylene Ketones [作者：HAN XIAODAN; ZHAO YULONG; MENG JIA; REN CHUANQING; LIU QUN,期刊：Journal of Organic Chemistry, 页码：5173-5178 , 文章类型： Article，,卷期：2012年77-11] A new benzannulation strategy that proceeds via a regiospecific [4 + 2] cycloaddition of readily available cyclobutenones and active methylene ketones has been developed. On the basis of this strategy, persubstituted phe... Copper(I)-Catalyzed Synthesis of 2,5-Disubstituted Furans and Thiophenes from Haloalkynes or 1,3-Diynes [作者：JIANG HUANFENG; ZENG WEI; LI YIBIAO; WU WANQING; HUANG LIANGBING; FU WEI,期刊：Journal of Organic Chemistry, 页码：5179-5183 , 文章类型： Article，,卷期：2012年77-11] A regioselective synthesis of 2,5-disubstituted furans using copper(I) catalyst from haloalkynes in a one-pot procedure has been reported. This chemistry proceeds through the hydration reaction of 1,3-diynes, which can b... Azepine Synthesis from Alkyl Azide and Propargylic Ester via Gold Catalysis [作者：LIU HENG; LI XIN; CHEN ZILI; HU WENXIANG,期刊：Journal of Organic Chemistry, 页码：5184-5190 , 文章类型： Article，,卷期：2012年77-11] An efficient new method was developed to synthesize multisubstituted 4, 5-dihydro-1H-azepine derivatives through the gold-catalyzed reaction of two molecules of propargylic esters with one molecule of alkyl azide. It was...