- Priming of CD8(+) T cells during central nervous system infection with a murine coronavirus is strain dependent
[作者:MacNamara, KC; Bender, SJ; Chua, MM; Watson, R; Weiss, SR,期刊:Journal of virology, 页码:6150-6160 , 文章类型: Article,,卷期:2008年82-13]
- Virus-specific CD8(+) T cells are critical for protection against neurotropic coronaviruses; however, central nervous system (CNS) infection with the recombinant JHM (RJHM) strain of mouse hepatitis virus (MHV) elicits a...
- Cell-type-specific tyrosine phosphorylation of the herpes simplex virus tegument protein VP11/12 encoded by gene UL46
[作者:Zahariadis, G; Wagner, MJ; Doepker, RC; Maciejko, JM; Crider, CM; Jerome, KR; Smiley, JR,期刊:Journal of virology, 页码:6098-6108 , 文章类型: Article,,卷期:2008年82-13]
- Cytotoxic T lymphocytes (CTL) and natural killer (NK) cells play key roles in limiting herpesvirus infections; consequently, many herpesviruses, including herpes simplex virus (HSV), have evolved diverse strategies to ev...
- Human parainfluenza virus type 2 V protein inhibits genome replication by binding to the L protein: Possible role in promoting viral fitness
[作者:Nishio, M; Ohtsuka, J; Tsurudome, M; Nosaka, T; Kolakofsky, D,期刊:Journal of virology, 页码:6130-6138 , 文章类型: Article,,卷期:2008年82-13]
- The human parainfluenza virus type 2 (hPIV2) V protein plays important roles in inhibiting the host interferon response and promoting virus growth, but its role in hPIV2 replication and transcription is not clear. A gree...
- Rotavirus infection accelerates type 1 diabetes in mice with established insulitis
[作者:Graham, KL; Sanders, N; Tan, Y; Allison, J; Kay, TWH; Coulson, BS,期刊:Journal of virology, 页码:6139-6149 , 文章类型: Article,,卷期:2008年82-13]
- Infection modulates type I diabetes, a common autoimmune disease characterized by the destruction of insulin-producing islet beta cells in the pancreas. Childhood rotavirus infections have been associated with exacerbati...
- Dendritic cell internalization of foot-and-mouth disease virus: Influence of heparan sulfate binding on virus uptake and induction of the immune response
[作者:Harwood, LJ; Gerber, H; Sobrino, F; Summerfield, A; McCullough, KC,期刊:Journal of virology, 页码:6379-6394 , 文章类型: Article,,卷期:2008年82-13]
- Dendritic cells (DC), which are essential for inducing and regulating immune defenses and responses, represent the critical target for vaccines against pathogens such as foot-and-mouth disease virus (FMDV). Although it i...
- RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis
[作者:Marshall, LJ; Moore, AC; Ohki, M; Kitabayashi, I; Patterson, D; Ornelles, DA,期刊:Journal of virology, 页码:6395-6408 , 文章类型: Article,,卷期:2008年82-13]
- The localization of the adenovirus E1B-55K-E4orf6 protein complex is critical for its function. Prior studies demonstrated that E4orf6 directs the nuclear localization of E1B-55K in human cells and in rodent cells that c...
- A seven-segmented influenza A virus expressing the influenza C virus glycoprotein HEF
[作者:Gao, QS; Brydon, EWA; Palese, P,期刊:Journal of virology, 页码:6419-6426 , 文章类型: Article,,卷期:2008年82-13]
- Influenza viruses are classified into three types: A, B, and C. The genomes of A- and B-type influenza viruses consist of eight RNA segments, whereas influenza C viruses only have seven RNAs. Both A and B influenza virus...
- Identification of a physiological phosphorylation site of the herpes simplex virus 1-encoded protein kinase Us3 which regulates its optimal catalytic activity in vitro and influences its function in infected cells
[作者:Kato, A; Tanaka, M; Yamamoto, M; Asai, R; Sata, T; Nishiyama, Y; Kawaguchi, Y,期刊:Journal of virology, 页码:6172-6189 , 文章类型: Article,,卷期:2008年82-13]
- Us3 is a serine/threonine protein kinase encoded by herpes simplex virus I (HSV-1). Here, we report the identification of a physiological Us3 phosphorylation site on serine at position 147 (Ser-147) which regulates its p...
- A filovirus-unique region of Ebola virus nucleoprotein confers aberrant migration and mediates its incorporation into virions
[作者:Shi, W; Huang, Y; Sutton-Smith, M; Tissot, B; Panico, M; Morris, HR; Dell, A; Haslam, SM; Boyington, J; Graham, BS; Yang, ZY; Nabell, GJ,期刊:Journal of virology, 页码:6190-6199 , 文章类型: Article,,卷期:2008年82-13]
- The Ebola virus nucleoprotein (NP) is an essential component of the nucleocapsid, required for filovirus particle formation and replication. Together with virion protein 35 (VP35) and VP24, this gene product gives rise t...
- Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus
[作者:Wei, CJ; Xu, L; Kong, WP; Shi, W; Canis, K; Stevens, J; Yang, ZY; Dell, A; Haslam, SM; Wilson, IA; Nabel, GJ,期刊:Journal of virology, 页码:6200-6208 , 文章类型: Article,,卷期:2008年82-13]
- Although the human transmission of avian H5N1 virus remains low, the prevalence of this highly pathogenic infection in avian species underscores the need for a preventive vaccine that can be made without eggs. Here, we s...
- Genetic analysis of Israel acute paralysis virus: Distinct clusters are circulating in the United States
[作者:Palacios, G; Hui, J; Quan, PL; Kalkstein, A; Honkavuori, KS; Bussetti, AV; Conlan, S; Evans, J; Chen, YP; vanEngelsdorp, D; Efrat, H; Pettis, J; Cox-Foster, D; Holmes, EC; Briese, T; Lipkin, WI,期刊:Journal of virology, 页码:6209-6217 , 文章类型: Article,,卷期:2008年82-13]
- Israel acute paralysis virus (IAPV) is associated with colony collapse disorder of honey bees. Nonetheless, its role in the pathogenesis of the disorder and its geographic distribution are unclear. Here, we report phylog...
|