- Induction of broad CD4(+) and CD8(+) T-cell responses and cross-neutralizing antibodies against hepatitis C virus by vaccination with Th1-adjuvanted polypeptides followed by defective alphaviral particles expressing envelope glycoproteins gpE1 and gpE2 and nonstructural proteins 3, 4, and 5
[作者:Lin, YL; Kwon, T; Polo, J; Zhu, YF; Coates, S; Crawford, K; Dong, C; Wininger, M; Hall, J; Selby, M; Coit, D; Medina-Selby, A; McCoin, C; Ng, P; Drane, D; Chien, D; Han, J; Vajdy, M; Houghtont, M,期刊:Journal of virology, 页码:7492-7503 , 文章类型: Article,,卷期:2008年82-15]
- Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chro...
- Herpes simplex virus type 1 ICP27 regulates expression of a variant, secreted form of glycoprotein C by an intron retention mechanism
[作者:Sedlackova, L; Perkins, KD; Lengyel, J; Strain, AK; van Santen, VL; Rice, SA,期刊:Journal of virology, 页码:7443-7455 , 文章类型: Article,,卷期:2008年82-15]
- We previously showed that herpes simplex virus type I (HSV-1) immediate-early (IE) protein ICP27 can posttranscriptionally stimulate mRNA accumulation from a transfected viral late gene encoding glycoprotein C (gC) (K. D...
- Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2
[作者:Netland, J; Meyerholz, DK; Moore, S; Cassell, M; Perlman, S,期刊:Journal of virology, 页码:7264-7275 , 文章类型: Article,,卷期:2008年82-15]
- Infection of humans with the severe acute respiratory syndrome coronavirus (SARS-CoV) results in substantial morbidity and mortality, with death resulting primarily from respiratory failure. While the lungs are the major...
- Primary human hepatocytes are susceptible to infection by hepatitis delta virus assembled with envelope proteins of woodchuck hepatitis virus
[作者:Gudima, S; He, YP; Chai, N; Bruss, V; Urban, S; Mason, W; Taylor, J,期刊:Journal of virology, 页码:7276-7283 , 文章类型: Article,,卷期:2008年82-15]
- Hepatitis B virus (HBV) and hepatitis delta virus (HDV) share the HBV envelope proteins. When woodchucks chronically infected with woodchuck hepatitis virus (WHV) are superinfected with HDV, they produce HDV with a WHV e...
- Visualization of the externalized VP2N termini of infectious human parvovirus B19
[作者:Kaufmann, B; Chipman, PR; Kostyuchenko, VA; Modrow, S; Rossmann, MG,期刊:Journal of virology, 页码:7306-7312 , 文章类型: Article,,卷期:2008年82-15]
- The structures of infectious human parvovirus B19 and empty wild-type particles were determined by cryoelectron microscopy (cryoEM) to 7.5-angstrom and 11.3 angstrom resolution, respectively, assuming icosahedral symmetr...
- Genetic analysis of the capsid gene of genotype GII.2 noroviruses
[作者:Iritani, N; Vennema, H; Siebenga, JJ; Siezen, RJ; Renckens, B; Seto, Y; Kaida, A; Koopmans, M,期刊:Journal of virology, 页码:7336-7345 , 文章类型: Article,,卷期:2008年82-15]
- Noroviruses (NoVs) are considered to be a major cause of acute nonbacterial gastroenteritis in humans. The NoV genus is genetically diverse, and genotype GII.4 has been most commonly identified worldwide in recent years....
- Limited maintenance of vaccine-induced simian immunodeficiency virus-specific CD8 T-cell receptor clonotypes after virus challenge
[作者:Smith, MZ; Asher, TE; Venturi, V; Davenport, MP; Douek, DC; Price, DA; Kent, SJ,期刊:Journal of virology, 页码:7357-7368 , 文章类型: Article,,卷期:2008年82-15]
- T-cell receptors (TCRs) govern the specificity, efficacy, and cross-reactivity of CD8 T cells. Here, we studied CD8 T-cell clonotypes from Mane-A*10(+) pigtail macaques responding to the simian immunodeficiency virus (SI...
- Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gp120 DNA prime-protein boost vaccination compared to gp120 protein-only vaccination
[作者:Vaine, M; Wang, S; Crooks, ET; Jiang, P; Montefiori, DC; Binley, J; Lu, S,期刊:Journal of virology, 页码:7369-7378 , 文章类型: Article,,卷期:2008年82-15]
- A major challenge in human immunodeficiency virus type 1 (HIV-1) vaccine development is to elicit potent and broadly neutralizing antibodies that are effective against primary viral isolates. Previously, we showed that D...
- Transmission of human immunodeficiency virus type 1 from a patient who developed AIDS to an elite suppressor
[作者:Bailey, JR; O'Connell, K; Yang, HC; Han, Y; Xu, J; Jilek, B; Williams, TM; Ray, SC; Siliciano, RF; Blankson, JN,期刊:Journal of virology, 页码:7395-7410 , 文章类型: Article,,卷期:2008年82-15]
- Elite suppressors (ES) are untreated human immunodeficiency virus type 1 (HIV-1)-infected patients who maintain viral loads of <50 copies/ml. The mechanisms involved in this control of viral replication remain unclear. P...
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