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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Slow-Onset Inhibition of the Fabl Enoyl Reductase from Francisella tularensis: Residence Time and in Vivo Activity [作者：LU HAO; ENGLAND KATHLEEN; ENDE CHRISTOPHER AM; TRUGLIO JAMES J; LUCKNER SYLVIA; REDDY B GOPAL; MARLENEE NICOLE L; KNUDSON SUSAN E; KNUDSON DENNIS L; BOWEN RICHARD A; KISKER CAROLINE; SLAYDEN RICHARD A; TONGE PETER J,期刊：ACS CHEMICAL BIOLOGY, 页码：221-231 , 文章类型： Article，,卷期：2009年4-3] Francisella tularensis is a highly virulent and contagious Gram- negative intracellular bacterium that causes the disease tularemia in mammals. The high infectivity and the ability of the bacterium to survive for weeks i... Regenerating Science: Stem Cells Back in the Mix [作者：MARTENS ERIC,期刊：ACS CHEMICAL BIOLOGY, 页码：145-145 , 文章类型： Editorial Material，,卷期：2009年4-3] Sheng Ding: Using Chemical Methods To Control Cell Fate [作者：BROWNLEE CHRISTEN,期刊：ACS CHEMICAL BIOLOGY, 页码：153-156 , 文章类型： Biographical-Item，,卷期：2009年4-3] Expanding the Repertoire of Fluorescent Calcium Sensors [作者：PALMER AMY E,期刊：ACS CHEMICAL BIOLOGY, 页码：157-159 , 文章类型： Article，,卷期：2009年4-3] Fluorescent indicators for calcium are incredibly powerful because they enable researchers to watch the movement of calcium ions in real time in living cells. The popular small molecule indicator Indo-1 has now been targ... Indo-1 Derivatives for Local Calcium Sensing [作者：BANNWARTH MICHAEL; CORREA IVAN R JR; SZTRETYE MONIKA; POUVREAU SANDRINE; FELLAY CINDY; AEBISCHER ANNINA; ROYER LEANDRO; RIOS EDUARDO; JOHNSSON KAI,期刊：ACS CHEMICAL BIOLOGY, 页码：179-190 , 文章类型： Article，,卷期：2009年4-3] The role of calcium in signal transduction relies on the precise spatial and temporal control of its concentration. The existing means to detect fluctuations in Ca2+ concentrations with adequate temporal and spatial reso... Alpha Anomers of iGb3 and Gb3 Stimulate Cytokine Production by Natural Killer T Cells [作者：YIN NING; LONG XIANGTIAN; GOFF RANDAL D; ZHOU DAPENG; CANTU CARLOS III; MATTNER JOCHEN; SAINT MEZARD PIERRE; TEYTON LUC; BENDELAC ALBERT; SAVAGE PAUL B,期刊：ACS CHEMICAL BIOLOGY, 页码：191-197 , 文章类型： Article，,卷期：2009年4-3] Natural killer T cells (NKT cells) respond to presentation of specific glycolipids with release of a variety of proinflammatory and immunomodulatory cytokines. The repertoire of glycolipid antigens for these cells includ... AR Inhibitors Identified by High-Throughput Microscopy Detection of Conformational Change and Subcellular Localization [作者：JONES JEREMY O; AN W FRANK; DIAMOND MARC I,期刊：ACS CHEMICAL BIOLOGY, 页码：199-208 , 文章类型： Article，,卷期：2009年4-3] Signaling via the androgen receptor (AR) plays an important role in human health and disease. All currently available anti-androgens prevent ligand access to the receptor, either by limiting androgen synthesis of by comp... The Molecular Basis of Species-Specific Ligand Activation of Trace Amine-Associated Receptor 1 (TAAR(1)) [作者：TAN EDWIN S; NAYLOR JOHN C; GROBAN ELI S; BUNZOW JAMES R; JACOBSON MATTHEW P; GRANDY DAVID K; SCANLAN THOMAS S,期刊：ACS CHEMICAL BIOLOGY, 页码：209-220 , 文章类型： Article，,卷期：2009年4-3] The trace amine-associated receptor 1 (TAAR(1)) is an aminergic G protein-coupled receptor (GPCR) potently activated by 3-iodothyronamine (1), an endogenous derivative of thyroid hormone. Structure-activity relationship ... Chemical Biology of Peroxynitrite: Kinetics, Diffusion, and Radicals [作者：FERRERSUETA GERARDO; RADI RAFAEL,期刊：ACS CHEMICAL BIOLOGY, 页码：161-177 , 文章类型： Review，,卷期：2009年4-3] Peroxynitrite is formed by the very fast reaction of nitric oxide and superoxide radicals, a reaction that kinetically competes with other routes that chemically consume or physically sequester the reagents. It can behav...