- miR-200 Regulates PDGF-D-Mediated Epithelial-Mesenchymal Transition, Adhesion, and Invasion of Prostate Cancer Cells
[作者：Kong, DJ; Li, YW; Wang, ZW; Banerjee, S; Ahmad, A; Kim, HRC; Sarkar, FH,期刊：Stem Cells, 页码：1712-1721 , 文章类型： Article，,卷期：2009年27-8]
- MicroRNAs have been implicated in tumor progression. Recent studies have shown that the miR-200 family regulates epithelial-mesenchymal transition (EMT) by targeting zinc-finger E-box binding homeobox 1 (ZEB1) and ZEB2. ...
- Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens
[作者：Kelly, JJP; Stechishin, O; Chojnacki, A; Lun, XQ; Sun, BC; Senger, DL; Forsyth, P; Auer, RN; Dunn, JF; Cairncross, JG; Parney, IF; Weiss, S,期刊：Stem Cells, 页码：1722-1733 , 文章类型： Article，,卷期：2009年27-8]
- Primary glial tumors of the central nervous system, most commonly glioblastoma multiforme (GBM), are aggressive lesions with a dismal prognosis. Despite identification and isolation of human brain tumor stem cells (BTSCs...
- Antigen-Specific T-Cell Response from Dendritic Cell Vaccination Using Cancer Stem-Like Cell-Associated Antigens
[作者：Xu, QJ; Liu, GT; Yuan, XP; Xu, ML; Wang, HQ; Ji, JF; Konda, B; Black, KL; Yu, JS,期刊：Stem Cells, 页码：1734-1740 , 文章类型： Article，,卷期：2009年27-8]
- Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, with current treatment remaining palliative. Immunotherapies harness the body's own immune system to target cancers and could overcome the limitat...
- Regulation of Neural Specification from Human Embryonic Stem Cells by BMP and FGF
[作者：LaVaute, TM; Yoo, YD; Pankratz, MT; Weick, JP; Gerstner, JR; Zhang, SC,期刊：Stem Cells, 页码：1741-1749 , 文章类型： Article，,卷期：2009年27-8]
- Inhibition of bone morphogenetic protein (BMP) signaling is required for vertebrate neural induction, and fibroblast growth factors (FGFs) may affect neural induction through phosphorylation at the linker region of Smad1...
- A Boost of BMP4 Accelerates the Commitment of Human Embryonic Stem Cells to the Endothelial Lineage
[作者：Goldman, O; Feraud, O; Boyer-Di Ponio, J; Driancourt, C; Clay, D; Le Bousse-Kerdiles, MC; Bennaceur-Griscelli, A; Uzan, G,期刊：Stem Cells, 页码：1750-1759 , 文章类型： Article，,卷期：2009年27-8]
- Embryoid bodies (EBs) generated during differentiation of human embryonic stem cells (hESCs) contain vascular-like structures, suggesting that commitment of mesoderm progenitors into endothelial cells occurs spontaneousl...
- Novel STAT3 Target Genes Exert Distinct Roles in the Inhibition of Mesoderm and Endoderm Differentiation in Cooperation with Nanog
[作者：Bourillot, PY; Aksoy, I; Schreiber, V; Wianny, F; Schulz, H; Hummel, O; Hubner, N; Savatier, P,期刊：Stem Cells, 页码：1760-1771 , 文章类型： Article，,卷期：2009年27-8]
- Leukemia inhibitory factor (LIF) activates the transcription factor signal transducer and activator of transcription 3 (STAT3), which results in the maintenance of mouse embryonic stem cells in the pluripotent state by i...
- Nicotinamide Rescues Human Embryonic Stem Cell-Derived Neuroectoderm from Parthanatic Cell Death
[作者：Cimadamore, F; Curchoe, CL; Alderson, N; Scott, F; Salvesen, G; Terskikh, AV,期刊：Stem Cells, 页码：1772-1781 , 文章类型： Article，,卷期：2009年27-8]
- Abundant cell death is observed when human embryonic stem cells (hESCs) undergo neuralization, a critical first step for future cell-based therapies addressing neurodegeneration. Using hESC neuralization as an in vitro m...
- EpCAM Is Involved in Maintenance of the Murine Embryonic Stem Cell Phenotype
[作者：Gonzalez, B; Denzel, S; Mack, B; Conrad, M; Gires, O,期刊：Stem Cells, 页码：1782-1791 , 文章类型： Article，,卷期：2009年27-8]
- Epithelial cell adhesion molecule EpCAM is a transmembrane glycoprotein that is expressed on subsets of normal epithelia, numerous stem-and progenitor-type cells, and most carcinomas and highly overexpressed on cancer-in...
- mAb 84, a Cytotoxic Antibody that Kills Undifferentiated Human Embryonic Stem Cells via Oncosis
[作者：Tan, HL; Fong, WJ; Lee, EH; Yap, M; Choo, A,期刊：Stem Cells, 页码：1792-1801 , 文章类型： Article，,卷期：2009年27-8]
The monoclonal antibody mAb 84, which binds to podocalyxin-like protein-1 (PODXL) on human embryonic stem cells (hESCs), was previously reported to bind and kill undifferentiated cells in in vitro and in vivo assays. ...
- Efficient Adipocyte and Osteoblast Differentiation from Mouse Induced Pluripotent Stem Cells by Adenoviral Transduction
[作者：Tashiro, K; Inamura, M; Kawabata, K; Sakurai, F; Yamanishi, K; Hayakawa, T; Mizuguchi, H,期刊：Stem Cells, 页码：1802-1811 , 文章类型： Article，,卷期：2009年27-8]
- Induced pluripotent stem (iPS) cells, which are generated from somatic cells by transducing four genes, are expected to have broad application to regenerative medicine. Although establishment of an efficient gene transfe...
- Coculture of Human Embryonic Stem Cells and Human Articular Chondrocytes Results in Significantly Altered Phenotype and Improved Chondrogenic Differentiation
[作者：Bigdeli, N; Karlsson, C; Strehl, R; Concaro, S; Hyllner, J; Lindahl, A,期刊：Stem Cells, 页码：1812-1821 , 文章类型： Article，,卷期：2009年27-8]
- Human embryonic stem (hES) cells have been suggested as a cell source for the repair of cartilage lesions. Here we studied how coculture with human articular chondrocytes affects the expansion potential, morphology, expr...
- Ionizing Radiation Induces Ataxia Telangiectasia Mutated-Dependent Checkpoint Signaling and G(2) But Not G(1) Cell Cycle Arrest in Pluripotent Human Embryonic Stem Cells
[作者：Momcilovic, O; Choi, S; Varum, S; Bakkenist, C; Schatten, G; Navara, C,期刊：Stem Cells, 页码：1822-1835 , 文章类型： Article，,卷期：2009年27-8]
- Human embryonic stem (ES) cells are highly sensitive to environmental insults including DNA damaging agents, responding with high levels of apoptosis. To understand the response of human ES cells to DNA damage, we invest...
- A Targeted Neuroglial Reporter Line Generated by Homologous Recombination in Human Embryonic Stem Cells
[作者：Xue, HP; Wu, S; Papadeas, ST; Spusta, S; Swistowska, AM; MacArthur, CC; Mattson, MP; Maragakis, NJ; Capecchi, MR; Rao, MS; Zeng, XM; Liu, Y,期刊：Stem Cells, 页码：1836-1846 , 文章类型： Article，,卷期：2009年27-8]
- In this study, we targeted Olig2, a basic helix-loop-helix transcription factor that plays an important role in motoneuron and oligodendrocyte development, in human embryonic stem cell (hESC) line BG01 by homologous reco...
- A Complex Role for FGF-2 in Self-Renewal, Survival, and Adhesion of Human Embryonic Stem Cells
[作者：Eiselleova, L; Matulka, K; Kriz, V; Kunova, M; Schmidtova, Z; Neradil, J; Tichy, B; Dvorakova, D; Pospisilova, S; Hampl, A; Dvorak, P,期刊：Stem Cells, 页码：1847-1857 , 文章类型： Article，,卷期：2009年27-8]
- The transcription program that is responsible for the pluripotency of human ESCs (hESCs) is believed to be comaintained by exogenous fibroblast growth factor-2 (FGF-2), which activates FGF receptors (FGFRs) and stimulate...
- Smad, PI3K/Akt, and Wnt-Dependent Signaling Pathways Are Involved in BMP-4-Induced ESC Self-Renewal
[作者：Lee, MY; Lim, HW; Lee, SH; Han, HJ,期刊：Stem Cells, 页码：1858-1868 , 文章类型： Article，,卷期：2009年27-8]
- It is known that bone morphogenetic protein 4 (BMP-4) has a diverse effect on ESCs. However, its precise mechanism in mouse ESCs is not fully understood. We evaluated the effect of BMP-4 on ESC proliferation and its rela...
- Wnt3a-Induced Mesoderm Formation and Cardiomyogenesis in Human Embryonic Stem Cells
[作者：Tran, TH; Wang, XR; Browne, C; Zhang, Y; Schinke, M; Izumo, S; Burcin, M,期刊：Stem Cells, 页码：1869-1878 , 文章类型： Article，,卷期：2009年27-8]
- In vitro differentiation of human embryonic stem cells (hESCs) into pure human cardiomyocytes (hESCMs) would present a powerful tool to further the creation of cell models designed to advance preclinical drug development...
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