- The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo
[作者:Soler-Llavina, GJ; Fuccillo, MV; Ko, J; Sudhof, TC; Malenka, RC,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16502-16509 , 文章类型: Article,,卷期:2011年108-40]
- Synaptic cell adhesion molecules, including the neurexin ligands, neuroligins (NLs) and leucine-rich repeat transmembrane proteins (LRRTMs), are thought to organize synapse assembly and specify synapse function. To test ...
- InfoBiology by printed arrays of microorganism colonies for timed and on-demand release of messages
[作者:Palacios, MA; Benito-Pena, E; Manesse, M; Mazzeo, AD; LaFratta, CN; Whitesides, GM; Walt, DR,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16510-16514 , 文章类型: Article,,卷期:2011年108-40]
- This paper presents a proof-of-principle method, called InfoBiology, to write and encode data using arrays of genetically engineered strains of Escherichia coli with fluorescent proteins (FPs) as phenotypic markers. In I...
- E339 ... R416 salt bridge of nucleoprotein as a feasible target for influenza virus inhibitors
[作者:Shen, YF; Chen, YH; Chu, SY; Lin, MI; Hsu, HT; Wu, PY; Wu, CJ; Liu, HW; Lin, FY; Lin, G; Hsu, PH; Yang, AS; Cheng, YSE; Wu, YT; Wong, CH; Tsai, MD,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16515-16520 , 文章类型: Article,,卷期:2011年108-40]
- The nucleoprotein (NP) of the influenza virus exists as trimers, and its tail-loop binding pocket has been suggested as a potential target for antiinfluenza therapeutics. The possibility of NP as a drug target was valida...
- Conformation of self-assembled porphyrin dimers in liposome vesicles by phase-modulation 2D fluorescence spectroscopy
[作者:Lott, GA; Perdomo-Ortiz, A; Utterback, JK; Widom, JR; Aspuru-Guzik, A; Marcus, AH,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16521-16526 , 文章类型: Article,,卷期:2011年108-40]
- By applying a phase-modulation fluorescence approach to 2D electronic spectroscopy, we studied the conformation-dependent exciton coupling of a porphyrin dimer embedded in a phospholipid bilayer membrane. Our measurement...
- Results of the Regional Earthquake Likelihood Models (RELM) test of earthquake forecasts in California
[作者:Lee, YT; Turcotte, DL; Holliday, JR; Sachs, MK; Rundle, JB; Chen, CC; Tiampo, KF,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16533-16538 , 文章类型: Article,,卷期:2011年108-40]
- The Regional Earthquake Likelihood Models (RELM) test of earthquake forecasts in California was the first competitive evaluation of forecasts of future earthquake occurrence. Participants submitted expected probabilities...
- Thermodynamics of phase formation in the quantum critical metal Sr(3)Ru(2)O(7)
[作者:Rost, AW; Grigera, SA; Bruin, JAN; Perry, RS; Tian, D; Raghu, S; Kivelson, SA; Mackenzie, AP,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16549-16553 , 文章类型: Article,,卷期:2011年108-40]
- The behavior of matter near zero temperature continuous phase transitions, or "quantum critical points" is a central topic of study in condensed matter physics. In fermionic systems, fundamental questions remain unanswer...
- Valuation of plug-in vehicle life-cycle air emissions and oil displacement benefits
[作者:Michalek, JJ; Chester, M; Jaramillo, P; Samaras, C; Shiau, CSN; Lave, LB,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16554-16558 , 文章类型: Article,,卷期:2011年108-40]
- We assess the economic value of life-cycle air emissions and oil consumption from conventional vehicles, hybrid-electric vehicles (HEVs), plug-in hybrid-electric vehicles (PHEVs), and battery electric vehicles in the US....
- An algorithm-based topographical biomaterials library to instruct cell fate
[作者:Unadkat, HV; Hulsman, M; Cornelissen, K; Papenburg, BJ; Truckenmuller, RK; Post, GF; Uetz, M; Reinders, MJT; Stamatialis, D; van Blitterswijk, CA; de Boer, J,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16565-16570 , 文章类型: Article,,卷期:2011年108-40]
- It is increasingly recognized that material surface topography is able to evoke specific cellular responses, endowing materials with instructive properties that were formerly reserved for growth factors. This opens the w...
- Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex
[作者:Yoshida, K; Seo, HS; Debler, EW; Blobel, G; Hoelz, A,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16571-16576 , 文章类型: Article,,卷期:2011年108-40]
- So far, only a few of the interactions between the approximate to 30 nucleoporins comprising the modular structure of the nuclear pore complex have been defined at atomic resolution. Here we report the crystal structure,...
- Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification
[作者:Notari, M; Hu, Y; Koch, S; Lu, M; Ratnayaka, I; Zhong, S; Baer, C; Pagotto, A; Goldin, R; Salter, V; Candi, E; Melino, G; Lu, X,期刊:Proceedings of the National Academy of Sciences of the United States of America, 页码:16645-16650 , 文章类型: Article,,卷期:2011年108-40]
- Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is the most ancient member of the ASPP family of proteins and an evolutionarily conserved inhibitor of p53. iASPP is also a binding partner and negative regulator...
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