- Matching Glass-Forming Ability with the Density of the Amorphous Phase
[作者:Li, Y; Guo, Q; Kalb, JA; Thompson, CV,期刊:Science, 页码:1816-1819 , 文章类型: Article,,卷期:2008年322-5909]
- The density of the amorphous phase of metals is generally thought to be related to glass formation, but this correlation has not been demonstrated experimentally to date. In this work, systematic deflection measurements ...
- Stable Prenucleation Calcium Carbonate Clusters
[作者:Gebauer, D; Volkel, A; Colfen, H,期刊:Science, 页码:1819-1822 , 文章类型: Article,,卷期:2008年322-5909]
- Calcium carbonate forms scales, geological deposits, biominerals, and ocean sediments. Huge amounts of carbon dioxide are retained as carbonate ions, and calcium ions represent a major contribution to water hardness. Des...
- Avian Paternal Care Had Dinosaur Origin
[作者:Varricchio, DJ; Moore, JR; Erickson, GM; Norell, MA; Jackson, FD; Borkowski, JJ,期刊:Science, 页码:1826-1828 , 文章类型: Article,,卷期:2008年322-5909]
- The repeated discovery of adult dinosaurs in close association with egg clutches leads to speculation over the type and extent of care exhibited by these extinct animals for their eggs and young. To assess parental care ...
- Orbital Identification of Carbonate-Bearing Rocks on Mars
[作者:Ehlmann, BL; Mustard, JF; Murchie, SL; Poulet, F; Bishop, JL; Brown, AJ; Calvin, WM; Clark, RN; Des Marais, DJ; Milliken, RE; Roach, LH; Roush, TL; Swayze, GA; Wray, JJ,期刊:Science, 页码:1828-1832 , 文章类型: Article,,卷期:2008年322-5909]
- Geochemical models for Mars predict carbonate formation during aqueous alteration. Carbonate- bearing rocks had not previously been detected on Mars' surface, but Mars Reconnaissance Orbiter mapping reveals a regional ro...
- The Circadian Clock in Arabidopsis Roots Is a Simplified Slave Version of the Clock in Shoots
[作者:James, AB; Monreal, JA; Nimmo, GA; Kelly, CL; Herzyk, P; Jenkins, GI; Nimmo, HG,期刊:Science, 页码:1832-1835 , 文章类型: Article,,卷期:2008年322-5909]
- The circadian oscillator in eukaryotes consists of several interlocking feedback loops through which the expression of clock genes is controlled. It is generally assumed that all plant cells contain essentially identical...
- Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A
[作者:Sankaran, VG; Menne, TF; Xu, J; Akie, TE; Lettre, G; Van Handel, B; Mikkola, HKA; Hirschhorn, JN; Cantor, AB; Orkin, SH,期刊:Science, 页码:1839-1842 , 文章类型: Article,,卷期:2008年322-5909]
- Differences in the amount of fetal hemoglobin (HbF) that persists into adulthood affect the severity of sickle cell disease and the beta-thalassemia syndromes. Genetic association studies have identified sequence variant...
- CRISPR Interference Limits Horizontal Gene Transfer in Staphylococci by Targeting DNA
[作者:Marraffini, LA; Sontheimer, EJ,期刊:Science, 页码:1843-1845 , 文章类型: Article,,卷期:2008年322-5909]
- Horizontal gene transfer (HGT) in bacteria and archaea occurs through phage transduction, transformation, or conjugation, and the latter is particularly important for the spread of antibiotic resistance. Clustered, regul...
- A Conserved Molecular Framework for Compound Leaf Development
[作者:Blein, T; Pulido, A; Vialette-Guiraud, A; Nikovics, K; Morin, H; Hay, A; Johansen, IE; Tsiantis, M; Laufs, P,期刊:Science, 页码:1835-1839 , 文章类型: Article,,卷期:2008年322-5909]
- Diversity in leaf shape is produced by alterations of the margin: for example, deep dissection leads to leaflet formation and less- pronounced incision results in serrations or lobes. By combining gene silencing and muta...
- Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters
[作者:Core, LJ; Waterfall, JJ; Lis, JT,期刊:Science, 页码:1845-1848 , 文章类型: Article,,卷期:2008年322-5909]
- RNA polymerases are highly regulated molecular machines. We present a method ( global run-on sequencing, GRO-seq) that maps the position, amount, and orientation of transcriptionally engaged RNA polymerases genome- wide....
- Divergent Transcription from Active Promoters
[作者:Seila, AC; Calabrese, JM; Levine, SS; Yeo, GW; Rahl, PB; Flynn, RA; Young, RA; Sharp, PA,期刊:Science, 页码:1849-1851 , 文章类型: Article,,卷期:2008年322-5909]
- Transcription initiation by RNA polymerase II ( RNAPII) is thought to occur unidirectionally from most genes. Here, we present evidence of widespread divergent transcription at protein- encoding gene promoters. Transcrip...
- RNA Exosome Depletion Reveals Transcription Upstream of Active Human Promoters
[作者:Preker, P; Nielsen, J; Kammler, S; Lykke-Andersen, S; Christensen, MS; Mapendano, CK; Schierup, MH; Jensen, TH,期刊:Science, 页码:1851-1854 , 文章类型: Article,,卷期:2008年322-5909]
- Studies have shown that the bulk of eukaryotic genomes is transcribed. Transcriptome maps are frequently updated, but low- abundant transcripts have probably gone unnoticed. To eliminate RNA degradation, we depleted the ...
- The Antisense Transcriptomes of Human Cells
[作者:He, YP; Vogelstein, B; Velculescu, VE; Papadopoulos, N; Kinzler, KW,期刊:Science, 页码:1855-1857 , 文章类型: Article,,卷期:2008年322-5909]
- Transcription in mammalian cells can be assessed at a genome- wide level, but it has been difficult to reliably determine whether individual transcripts are derived from the plus or minus strands of chromosomes. This dis...
- Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy
[作者:Freudiger, CW; Min, W; Saar, BG; Lu, S; Holtom, GR; He, CW; Tsai, JC; Kang, JX; Xie, XS,期刊:Science, 页码:1857-1861 , 文章类型: Article,,卷期:2008年322-5909]
- Label- free chemical contrast is highly desirable in biomedical imaging. Spontaneous Raman microscopy provides specific vibrational signatures of chemical bonds, but is often hindered by low sensitivity. Here we report a...
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