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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Hematopoietic stem cell responsiveness to exogenous signals is limited by Caspase-3 [作者：Janzen, V; Fleming, HE; Riedt, T; Karlsson, G; Riese, MJ; Lo Celso, C; Reynolds, G; Milne, CD; Paige, CJ; Karlsson, S; Woo, M; Scadden, DT,期刊：Cell Stem Cell, 页码：584-594 , 文章类型： Article，,卷期：2008年2-6] Limited responsiveness to inflammatory cytokines is a feature of adult hematopoietic stem cells and contributes to the relative quiescence and durability of the stem cell population in vivo. Here we report that the execu... Caspase activity mediates the differentiation of embryonic stem cells [作者：Fujita, J; Crane, AM; Souza, MK; Dejosez, M; Kyba, M; Flavell, RA; Thomson, JA; Zwaka, TP,期刊：Cell Stem Cell, 页码：595-601 , 文章类型： Article，,卷期：2008年2-6] Embryonic stem cells (ESCs) are capable of indefinite self-renewal while retaining the ability to differentiate to any of the three germ layers that give rise to all somatic cell types. An emerging view is that a core se... High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells [作者：Desbordes, SC; Placantonakis, DG; Ciro, A; Socci, ND; Lee, G; Djaballah, H; Studer, L,期刊：Cell Stem Cell, 页码：602-612 , 文章类型： Article，,卷期：2008年2-6] High-throughput screening (HTS) of chemical libraries has become a critical tool in basic biology and drug discovery. However, its implementation and the adaptation of high-content assays to human embryonic stem cells (h... Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse [作者：Windrem, MS; Schanz, SJ; Guo, M; Tian, GF; Washco, V; Stanwood, N; Rasband, M; Roy, NS; Nedergaard, M; Havton, LA; Wang, S; Goldman, SA,期刊：Cell Stem Cell, 页码：553-565 , 文章类型： Article，,卷期：2008年2-6] Congenitally hypomyelinated shiverer mice fail to generate compact myelin and die by 18-21 weeks of age. Using multifocal anterior and posterior fossa delivery of sorted fetal human glial progenitor cells into neonatal s... Efficient homing of multipotent adult mesenchymal stem cells depends on FROUNT-mediated clustering of CCR2 [作者：Belema-Bedada, F; Uchida, S; Martire, A; Kostin, S; Braun, T,期刊：Cell Stem Cell, 页码：566-575 , 文章类型： Article，,卷期：2008年2-6] Circulating stem cells of different origin have been demonstrated to improve repair of various organs both after systemic and local application, although the mechanisms that cause these effects are still not fully unders... PUMA regulates intestinal progenitor cell radiosensitivity and gastrointestinal syndrome [作者：Qiu, W; Carson-Walter, EB; Liu, H; Epperly, M; Greenberger, JS; Zambetti, GP; Zhang, L; Yu, J,期刊：Cell Stem Cell, 页码：576-583 , 文章类型： Article，,卷期：2008年2-6] Radiation is one of the most effective cancer treatments. However, gastrointestinal (GI) syndrome is a major limiting factor in abdominal and pelvic radiotherapy. The loss of crypt stem cells or villus endothelial cells ... Fiona Watt, ISSCR's president elect [作者：Nicholls, H,期刊：Cell Stem Cell, 页码：534-535 , 文章类型： Biographical-Item，,卷期：2008年2-6] Cell Stem Cell, one year on [作者：Sweet, DJ,期刊：Cell Stem Cell, 页码：509-509 , 文章类型： Editorial Material，,卷期：2008年2-6] Self-renewal and differentiation at Cell Stem Cell [作者：Zon, LI,期刊：Cell Stem Cell, 页码：510-510 , 文章类型： Editorial Material，,卷期：2008年2-6] Epithelial-mesenchymal transition and the stem cell phenotype [作者：Radisky, DC; LaBarge, MA,期刊：Cell Stem Cell, 页码：511-512 , 文章类型： Editorial Material，,卷期：2008年2-6] Epithelial-mesenchymal transition (EMT) is a developmental process in which epithelial cells acquire the motile, migratory properties of mesenchymal cells. In a recent issue of Cell, Mani et al. (2008) show that inductio... Home is where the heart is: Via the FROUNT [作者：Zannettino, ACW; Psaltis, PJ; Gronthos, S,期刊：Cell Stem Cell, 页码：513-514 , 文章类型： Editorial Material，,卷期：2008年2-6] In this issue of Cell Stem Cell, Belema-Bedada et al. (2008) describe a novel mechanism by which bone marrow-derived adult mesenchymal stem cells migrate to sites of damaged heart tissue. This process is dependent on the... Rehabilitation of a contract killer: Caspase-3 directs stem cell differentiation [作者：Abdul-Ghani, M; Megeney, LA,期刊：Cell Stem Cell, 页码：515-516 , 文章类型： Editorial Material，,卷期：2008年2-6] Activation of caspase-3 is generally acknowledged as a penultimate step in apoptotic cell death pathways. Two studies in this issue of Cell Stem Cell (Fujita et al., 2008; Janzen et al., 2008) provide compelling data to ... Puma: Mauling the intestinal crypt [作者：Clarke, AR,期刊：Cell Stem Cell, 页码：517-518 , 文章类型： Editorial Material，,卷期：2008年2-6] Cancer therapies utilizing chemotherapy or radiotherapy are constrained by risk of intestinal stem cell death. In this issue of Cell Stem Cell, Qiu et al. report that Puma deletion prevents intestinal degeneration follow... Rescue of congenital hypomyelination by progenitor cell transplantation [作者：Trapp, BD,期刊：Cell Stem Cell, 页码：519-520 , 文章类型： Editorial Material，,卷期：2008年2-6] Replacement of myelin-forming cells is an attractive but unproven therapy for inherited and acquired myelin diseases. In this issue of Cell Stem Cell, Windrem et al. (2008) describe the first progenitor cell transplantat... Identifying under- and overperforming countries in research related to human embryonic stem cells [作者：Levine, AD,期刊：Cell Stem Cell, 页码：521-524 , 文章类型： Editorial Material，,卷期：2008年2-6] A combined chemical and genetic approach for the generation of induced pluripotent stem cells [作者：Shi, Y; Do, JT; Desponts, C; Hahm, HS; Scholer, HR; Ding, S,期刊：Cell Stem Cell, 页码：525-528 , 文章类型： Editorial Material，,卷期：2008年2-6]