- N-acylphosphatidylethanolamine, a Gut-Derived Circulating Factor Induced by Fat Ingestion, Inhibits Food Intake
[作者：Gillum, MP; Zhang, D; Zhang, XM; Erion, DM; Jamison, RA; Choi, C; Dong, J; Shanabrough, M; Duenas, HR; Frederick, DW; Hsiao, JJ; Horvath, TL; Lo, CM; Tso, P; Cline, GW; Shulman, GI,期刊：Cell, 页码：813-824 , 文章类型： Article，,卷期：2008年135-5]
- N-acylphosphatidylethanolamines (NAPEs) are a relatively abundant group of plasma lipids of unknown physiological significance. Here, we show that NAPEs are secreted into circulation from the small intestine in response ...
- Motor Deficit in a Drosophila Model of Mucolipidosis Type IV due to Defective Clearance of Apoptotic Cells
[作者：Venkatachalam, K; Long, AA; Elsaesser, R; Nikolaeva, D; Broadie, K; Montell, C,期刊：Cell, 页码：838-851 , 文章类型： Article，,卷期：2008年135-5]
- Disruption of the Transient Receptor Potential (TRP) mucolipin 1 (TRPML1) channel results in the neurodegenerative disorder mucolipidosis type IV (MLIV), a lysosomal storage disease with severe motor impairments. The mec...
- Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum
[作者：Yadav, VK; Ryu, JH; Suda, N; Tanaka, KF; Gingrich, JA; Schuetz, GN; Glorieux, FH; Chiang, CY; Zajac, JD; Insogna, KL; Mann, JJ; Hen, R; Ducy, P; Karsenty, G,期刊：Cell, 页码：825-837 , 文章类型： Article，,卷期：2008年135-5]
- Loss- and gain-of-function mutations in the broadly expressed gene Lrp5 affect bone formation, causing osteoporosis and high bone mass, respectively. Although Lrp5 is viewed as a Wnt coreceptor, osteoblast-specific disru...
- Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma
[作者：Zhan, LX; Rosenberg, A; Bergami, KC; Yu, M; Xuan, ZY; Jaffe, AB; Allred, C; Muthuswamy, SK,期刊：Cell, 页码：865-878 , 文章类型： Article，,卷期：2008年135-5]
- Loss of cell polarity proteins such as Scribble induces neoplasia in Drosophila by promoting uncontrolled proliferation. In mammals, the role that polarity proteins play during tumorigenesis is not well understood. Here,...
- Aneuploidy Underlies Rapid Adaptive Evolution of Yeast Cells Deprived of a Conserved Cytokinesis Motor
[作者：Rancati, G; Pavelka, N; Fleharty, B; Noll, A; Trimble, R; Walton, K; Perera, A; Staehling-Hampton, K; Seidel, CW; Li, R,期刊：Cell, 页码：879-893 , 文章类型： Article，,卷期：2008年135-5]
- The ability to evolve is a fundamental feature of biological systems, but the mechanisms underlying this capacity and the evolutionary dynamics of conserved core processes remain elusive. We show that yeast cells deleted...
- Evolution in a Test Tube: The Hatchet before the Scalpel
[作者：Rando, OJ,期刊：Cell, 页码：789-791 , 文章类型： Editorial Material，,卷期：2008年135-5]
- Gene duplication provides an organism with a rich source of genetic material for tinkering by selection during evolution. In this issue, Rancati et al. (2008) report that extensive polyploidy and aneuploidy are the initi...
- Anchorage of Microtubule Minus Ends to Adherens Junctions Regulates Epithelial Cell-Cell Contacts
[作者：Meng, W; Mushika, Y; Ichii, T; Takeichi, M,期刊：Cell, 页码：948-959 , 文章类型： Article，,卷期：2008年135-5]
- Epithelial cells contain noncentrosomal microtubules (MTs), whose minus ends are oriented apically. In contrast with the well-known interactions of the minus ends with the centrosome, little is known about the terminatio...
- A New Component in Synaptic Plasticity: Upregulation of Kinesin in the Neurons of the Gill-Withdrawal Reflex
[作者：Puthanveettil, SV; Monje, FJ; Miniaci, MC; Choi, YB; Karl, KA; Khandros, E; Gawinowicz, MA; Sheetz, MP; Kandel, ER,期刊：Cell, 页码：960-973 , 文章类型： Article，,卷期：2008年135-5]
- To explore how gene products, required for the initiation of synaptic growth, move from the cell body of the sensory neuron to its presynaptic terminals, and from the cell body of the motor neuron to its postsynaptic den...
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