- Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: Results from a phase II study
[作者：Cohen, EEW; Rosen, LS; Vokes, EE; Kies, MS; Forastiere, AA; Worden, FP; Kane, MA; Sherman, E; Kim, S; Bycott, P; Tortorici, M; Shalinsky, DR; Liau, KF; Cohen, RB,期刊：Journal of clinical oncology, 页码：4708-4713 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Patients with advanced, incurable thyroid cancer not amenable to surgery or radioactive iodine (I-131) therapy have few satisfactory therapeutic options. This multi-institutional study assessed the activity and s...
- Phase II trial of sorafenib in advanced thyroid cancer
[作者：Gupta-Abramson, V; Troxel, AB; Nellore, A; Puttaswamy, K; Redlinger, M; Ransone, K; Mandel, SJ; Flaherty, KT; Loevner, LA; O'Dwyer, PJ; Brose, MS,期刊：Journal of clinical oncology, 页码：4714-4719 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Given the molecular pathophysiology of thyroid cancer and the spectrum of kinases inhibited by sorafenib, including Raf kinase, vascular endothelial growth factor receptors, platelet-derived growth factor recepto...
- Better off dead: Suicidal thoughts in cancer patients
[作者：Walker, J; Waters, RA; Murray, G; Swanson, H; Hibberd, CJ; Rush, RW; Storey, DJ; Strong, VA; Fallon, MT; Wall, LR; Sharpe, M,期刊：Journal of clinical oncology, 页码：4725-4730 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Cancer is associated with an increased risk of suicide and attempted suicide. However, we do not know how many cancer patients have thoughts that they would be better off dead or thoughts of hurting themselves. T...
- Incidence of suicide in persons with cancer
[作者：Misono, S; Weiss, NS; Fann, JR; Redman, M; Yueh, B,期刊：Journal of clinical oncology, 页码：4731-4738 , 文章类型： Article，,卷期：2008年26-29]
- Purpose The purpose of this study was to characterize suicide rates among patients with cancer in the United States and identify patient and disease characteristics associated with higher suicide rates. Prior studies, mo...
- AIDS-related malignancies: State of the art and therapeutic challenges
[作者：Spano, JP; Costagliola, D; Katlama, C; Mounier, N; Oksenhendler, E; Khayat, D,期刊：Journal of clinical oncology, 页码：4834-4842 , 文章类型： Review，,卷期：2008年26-29]
- Despite the impact of combination antiretroviral therapy (cART) on HIV-related mortality, malignancy remains an important cause of death in the current era. Although the advent of cART has resulted in reductions in the i...
- Performance of BRCA1/2 mutation prediction models in Asian Americans
[作者：Kurian, AW; Gong, GD; Chun, NM; Mills, MA; Staton, AD; Kingham, KE; Crawford, BB; Lee, R; Chan, S; Donlon, SS; Ridge, Y; Panabaker, K; West, DW; Whittemore, AS; Ford, JM,期刊：Journal of clinical oncology, 页码：4752-4758 , 文章类型： Article，,卷期：2008年26-29]
- Purpose There are established differences in breast cancer epidemiology between Asian and white individuals, but little is known about hereditary breast cancer in Asian populations. Although increasing numbers of Asian i...
- Monosomal karyotype in acute myeloid leukemia: A better indicator of poor prognosis than a complex karyotype
[作者：Breems, DA; Van Putten, WLJ; De Greef, GE; Van Zelderen-Bhola, SL; Gerssen-Schoorl, KBJ; Mellink, CHM; Nieuwint, A; Jotterand, M; Hagemeijer, A; Beverloo, HB; Lowenberg, B,期刊：Journal of clinical oncology, 页码：4791-4797 , 文章类型： Article，,卷期：2008年26-29]
- Purpose To investigate the prognostic value of various cytogenetic components of a complex karyotype in acute myeloid leukemia (AML). Patients and Methods Cytogenetics and overall survival (OS) were analyzed in 1,975 AML...
- Parents' views of cancer-directed therapy for children with no realistic chance for cure
[作者：Mack, JW; Joffe, S; Hilden, JM; Watterson, J; Moore, C; Weeks, JC; Wolfe, J,期刊：Journal of clinical oncology, 页码：4759-4764 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Previous literature suggests that parents often wish to continue cancer-directed therapy for their children with incurable cancer. We assessed parents' experiences with treatment for their children with cancer an...
- Prediction of survival in multiple myeloma based on gene expression profiles reveals cell cycle and chromosomal instability signatures in high-risk patients and hyperdiploid signatures in low-risk patients: A study of the intergroupe francophone du myelome
[作者：Decaux, O; Lode, L; Magrangeas, F; Charbonnel, C; Gouraud, W; Jezequel, P; Attal, M; Harousseau, JL; Moreau, P; Bataille, R; Campion, L; Avert-Loiseau, H; Minvielle, S,期刊：Journal of clinical oncology, 页码：4798-4805 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Survival of patients with multiple myeloma is highly heterogeneous, from periods of a few weeks to more than 10 years. We used gene expression profiles of myeloma cells obtained at diagnosis to identify broadly a...
- Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progression
[作者：Khorashad, JS; de Lavallade, H; Apperley, JF; Milojkovic, D; Reid, AG; Bua, M; Szydlo, R; Olavarria, E; Kaeda, J; Goldman, JM; Marin, D,期刊：Journal of clinical oncology, 页码：4806-4813 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Kinase domain (KD) mutations in the BCR-ABL gene are associated with resistance to imatinib in chronic myeloid leukemia (CML) but their incidence and prognostic significance in chronic phase (CP) patients without...
- Cognitive and adaptive outcome in extracerebellar low-grade brain tumors in children: A report from the children's oncology group
[作者：Ris, MD; Beebe, DW; Armstrong, FD; Fontanesi, J; Holmes, E; Sanford, RA; Wisoff, JH,期刊：Journal of clinical oncology, 页码：4765-4770 , 文章类型： Article，,卷期：2008年26-29]
- Purpose To determine whether pediatric patients treated with surgery only for low-grade tumors in the cerebral hemispheres, supratentorial midline, and exophytic brainstem evidence neurocognitive, academic, adaptive, or ...
- Del(6)(q22) and BCL6 Rearrangements in primary CNS lymphoma are indicators of an aggressive clinical course
[作者：Cady, FM; O'Neill, BP; Law, ME; Decker, PA; Kurtz, DM; Giannini, C; Porter, AB; Kurtin, PJ; Johnston, PB; Dogan, A; Remstein, ED,期刊：Journal of clinical oncology, 页码：4814-4819 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Primary CNS lymphoma (PCNSL) is an aggressive lymphoma but clinically validated biologic markers that can predict natural history to tailor treatment according to risk are lacking. Several genetic changes includi...
- Lower osteopontin plasma levels are associated with superior outcomes in advanced non-small-cell lung cancer patients receiving platinum-based chemotherapy: SWOG study S0003
[作者：Mack, PC; Redman, MW; Chansky, K; Williamson, SK; Farneth, NC; Lara, PN; Franklin, WA; Le, QT; Crowley, JJ; Gandara, DR,期刊：Journal of clinical oncology, 页码：4771-4776 , 文章类型： Article，,卷期：2008年26-29]
- Purpose S0003 was a phase III trial of carboplatin/paclitaxel with or without the hypoxic cytotoxin tirapazamine in patients with advanced or metastatic non-small-cell lung cancer (NSCLC). We investigated the relationshi...
- Interleukin-6, cortisol, and depressive symptoms in ovarian cancer patients
[作者：Lutgendorf, SK; Weinrib, AZ; Penedo, F; Russell, D; DeGeest, K; Costanzo, ES; Henderson, PJ; Sephton, SE; Rohleder, N; Lucci, JA; Cole, S; Sood, AK; Lubaroff, DM,期刊：Journal of clinical oncology, 页码：4820-4827 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Inflammatory processes have been implicated in the pathogenesis of both depression and cancer. Links between depressive symptoms, interleukin-6 (IL-6), and cortisol dysregulation have been demonstrated in cancer ...
- Zoledronic acid prevents bone loss in premenopausal women undergoing adjuvant chemotherapy for early-stage breast cancer
[作者：Hershman, DL; McMahon, DJ; Crew, KD; Cremers, S; Irani, D; Cucchiara, G; Brafman, L; Shane, E,期刊：Journal of clinical oncology, 页码：4739-4745 , 文章类型： Article，,卷期：2008年26-29]
- Purpose Adjuvant chemotherapy for breast cancer (BC) may be associated with increased rates of bone loss and decreased bone mineral density (BMD) and may lead to premature osteoporosis and increased fracture risk. We exa...
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