- Isolation and characterization of a novel peptide, osteoblast activating peptide (OBAP), associated with osteoblast differentiation and bone formation
[作者:Fukushima, N; Hiraoka, K; Shirachi, I; Kojima, M; Nagata, K,期刊:Biochemical and Biophysical Research Communications, 页码:157-163 , 文章类型: Article,,卷期:2010年400-1]
- A long-standing goal in bone loss treatment has been to develop bone-rebuilding anabolic agents that can potentially be used to treat bone-related disorders. To purify and isolate a novel anabolic that acts to osteoblast...
- Dual oxidase in the intestinal epithelium of zebrafish larvae has anti-bacterial properties
[作者:Flores, MV; Crawford, KC; Pullin, LM; Hall, CJ; Crosier, KE; Crosier, PS,期刊:Biochemical and Biophysical Research Communications, 页码:164-168 , 文章类型: Article,,卷期:2010年400-1]
- Reactive oxygen species (ROS) function in a range of physiological processes such as growth, metabolism and signaling, and also have a pathological role. Recent research highlighted the requirement for ROS generated by d...
- In vitro antiamyloidogenic properties of 1,4-naphthoquinones
[作者:Bermejo-Bescos, P; Martin-Aragon, S; Jimenez-Aliaga, KL; Ortega, A; Molina, MT; Buxaderas, E; Orellana, G; Csaky, AG,期刊:Biochemical and Biophysical Research Communications, 页码:169-174 , 文章类型: Article,,卷期:2010年400-1]
- The aim of this study is to find out whether several 1,4-naphthoquinones (1,4-NQ) can interact with the amyloidogenic pathway of the amyloid precursor protein processing, particularly targeting at beta-secretase (BACE), ...
- Transcriptional regulation of a brown adipocyte-specific gene, UCP1, by KLF11 and KLF15
[作者:Yamamoto, K; Sakaguchi, M; Medina, RJ; Niida, A; Sakaguchi, Y; Miyazaki, M; Kataoka, K; Huh, N,期刊:Biochemical and Biophysical Research Communications, 页码:175-180 , 文章类型: Article,,卷期:2010年400-1]
- Several growth factors and transcription factors have been reported to play important roles in brown adipocyte differentiation and modulation of thermogenic gene expression, especially the expression of UCP1. In this stu...
- Intermediate structure between chromatin fibers and chromosome revealed by mechanical stretching and SPM measurement
[作者:Ikeda, K; Mizutani, T; Hoshi, O; Ushiki, T; Haga, H; Kawabata, K,期刊:Biochemical and Biophysical Research Communications, 页码:181-186 , 文章类型: Article,,卷期:2010年400-1]
- The morphology of chromosomes (certain rod-shaped structures) is highly reproducible despite the high condensation of chromatin fibers (similar to 1 mm) into chromosomes (similar to 1 mu m). However, the mechanism underl...
- Differential gene expression profiling in blood from patients with digestive system cancers
[作者:Masao, H; Sakai, Y; Yamashita, T; Yamashita, T; Sakai, A; Mizukoshi, E; Nakamoto, Y; Tatsumi, I; Miyazaki, Y; Tanno, H; Kaneko, S,期刊:Biochemical and Biophysical Research Communications, 页码:7-15 , 文章类型: Article,,卷期:2010年400-1]
- To develop a non-invasive and sensitive diagnostic test for cancer using peripheral blood, we evaluated gene expression profiling of blood obtained from patients with cancer of the digestive system and normal subjects. T...
- TCR-induced Akt serine 473 phosphorylation is regulated by protein kinase C-alpha
[作者:Yang, LF; Qiao, GL; Ying, HY; Zhang, JA; Yin, F,期刊:Biochemical and Biophysical Research Communications, 页码:16-20 , 文章类型: Article,,卷期:2010年400-1]
- Akt signaling plays a central role in T cell functions, such as proliferation, apoptosis, and regulatory T cell development. Phosphorylation at Set(473) in the hydrophobic motif, along with Thr(308) in its activation loo...
- Neonatal mouse testis-derived multipotent germline stem cells improve the cardiac function of acute ischemic heart mouse model
[作者:Iwasa, T; Baba, S; Doi, H; Kaichi, S; Yokoo, N; Mima, T; Kanatsu-Shinohara, M; Shinohara, T; Nakahata, T; Heike, T,期刊:Biochemical and Biophysical Research Communications, 页码:27-33 , 文章类型: Article,,卷期:2010年400-1]
- Multipotent germline stem (mGS) cells have been established from neonatal mouse testes. We previously reported that undifferentiated mGS cells are phenotypically similar to embryonic stem cells and that fetal liver kinas...
- Osteogenic differentiation of mouse mesenchymal progenitor cell, Kusa-A1 is promoted by mammalian transcriptional repressor Rbpj
[作者:Wang, SC; Kawashima, N; Sakamoto, K; Katsube, K; Umezawa, A; Suda, H,期刊:Biochemical and Biophysical Research Communications, 页码:39-45 , 文章类型: Article,,卷期:2010年400-1]
- Pluripotent mesenchymal stem cells possess the ability to differentiate into many cell types, but the precise mechanisms of differentiation are still unclear. Here, we provide evidence that Rbpj (recombination signal-bin...
- Tristetraprolin controls the stability of cIAP2 mRNA through binding to the 3 ' UTR of cIAP2 mRNA
[作者:Kim, CW; Kim, HK; Vo, MT; Lee, HH; Kim, HJ; Min, YJ; Cho, WJ; Park, JW,期刊:Biochemical and Biophysical Research Communications, 页码:46-52 , 文章类型: Article,,卷期:2010年400-1]
- cIAP2 is a key regulator of programmed cell death and the NF-kappa B pathway. Here, we investigated the post-transcriptional regulation of cIAP2 expression by tristetraprolin (TIP). Our results showed that overexpression...
- Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects
[作者:Samaan, G; Yugo, D; Rajagopalan, S; Wall, J; Donnell, R; Goldowitz, D; Gopalakrishnan, R; Venkatachalam, S,期刊:Biochemical and Biophysical Research Communications, 页码:60-65 , 文章类型: Article,,卷期:2010年400-1]
- The fork-head transcription factors are involved in a variety of physiological processes including development, aging, obesity, and cancer. The fork-head transcription factor FOXN3 has been implicated in cell cycle and t...
- Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway
[作者:Koike, S; Keino-Masu, K; Masu, M,期刊:Biochemical and Biophysical Research Communications, 页码:66-71 , 文章类型: Article,,卷期:2010年400-1]
- Autotaxin, encoded by the Enpp2 gene, generates lysophosphatidic acid (LPA) extracellularly, eliciting various cellular responses through specific LPA receptors. Previous studies have revealed that Enpp2(-/-) mice die at...
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