- Seson, a novel zinc finger protein, controls cilia integrity for the LR patterning during zebrafish embryogenesis
[作者:Kang, N; Ro, H; Park, Y; Kim, HT; Huh, TL; Rhee, M,期刊:Biochemical and Biophysical Research Communications, 页码:169-174 , 文章类型: Article,,卷期:2010年401-2]
- In zebrafish embryos, bilateral symmetry is broken by asymmetric nodal flow generated in Kupffer's vesicle (KV), the transient cilia-rich organ, analogous to the mouse node. Asymmetric nodal flow induces the asymmetric e...
- Drosophila CG10527 mutants are resistant to juvenile hormone and its analog methoprene
[作者:Zhang, HY; Tian, L; Tobe, S; Xiong, Y; Wang, SY; Lin, XD; Liu, YA; Bendena, W; Li, S; Zhang, YQ,期刊:Biochemical and Biophysical Research Communications, 页码:182-187 , 文章类型: Article,,卷期:2010年401-2]
- Juvenile hormone (JH) is critical for development, metamorphosis, and reproduction in insects. While the physiological importance of JH has been appreciated for decades, its biosynthetic pathway and molecular action rema...
- Three new powerful oseltamivir derivatives for inhibiting the neuraminidase of influenza virus
[作者:Wang, SQ; Cheng, XC; Dong, WL; Wang, RL; Chou, KC,期刊:Biochemical and Biophysical Research Communications, 页码:188-191 , 文章类型: Article,,卷期:2010年401-2]
- Owing to its unique function in assisting the release of newly formed virus particles from the surface of an infected cell, neuraminidase, an antigenic glycoprotein enzyme, is a main target for drug design against influe...
- Modulation of neutrophil apoptosis by murine pulmonary microvascular endothelial cell inducible nitric oxide synthase
[作者:Wang, LF; Mehta, S; Gillis, C; Law, C; Taneja, R,期刊:Biochemical and Biophysical Research Communications, 页码:207-212 , 文章类型: Article,,卷期:2010年401-2]
- Neutrophils contribute significantly to ALI (acute lung injury) through adhesion to pulmonary microvascular endothelial cells (PMEC), trans-PMEC migration and alveolar infiltration. Trans-PMEC migration delays expression...
- Development of a bioassay to screen for chemicals mimicking the anti-aging effects of calorie restriction
[作者:Chiba, T; Tsuchiya, T; Komatsu, T; Mori, R; Hayashi, H; Shimano, H; Spindler, SR; Shimokawa, I,期刊:Biochemical and Biophysical Research Communications, 页码:213-218 , 文章类型: Article,,卷期:2010年401-2]
- Suppression of the growth hormone/insulin-like growth factor-I pathway in Ames dwarf (DF) mice, and caloric restriction (CR) in normal mice extends lifespan and delays the onset of age-related disorders. In combination, ...
- Teasing apart a three-way symbiosis: Transcriptome analyses of Curvularia protuberata in response to viral infection and heat stress
[作者:Morsy, MR; Oswald, J; He, J; Tang, YH; Roossinck, MJ,期刊:Biochemical and Biophysical Research Communications, 页码:225-230 , 文章类型: Article,,卷期:2010年401-2]
- The fungus Curvularia protuberata carries a dsRNA virus. Curvularia thermal tolerance virus, and develops a three-way symbiotic relationship with plants to enable their survival in extreme soil temperatures. To learn abo...
- Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells
[作者:Liu, Y; Huo, ZX; Yan, BA; Lin, XP; Zhou, ZN; Liang, XQ; Zhu, WD; Liang, DD; Li, L; Liu, Y; Zhao, H; Sun, YF; Chen, YH,期刊:Biochemical and Biophysical Research Communications, 页码:231-237 , 文章类型: Article,,卷期:2010年401-2]
- Prolyl hydroxylases (PHDs) are dioxygenases that use oxygen as a co-substrate to hydroxylate proline residues. Three PHD isoforms (PHD1, PHD2 and PHD3) have been identified in mammalian cells. PHD3 expression is upregula...
- Arabidopsis DREB2C functions as a transcriptional activator of HsfA3 during the heat stress response
[作者:Chen, H; Hwang, JE; Lim, CJ; Kim, DY; Lee, SY; Lim, CO,期刊:Biochemical and Biophysical Research Communications, 页码:238-244 , 文章类型: Article,,卷期:2010年401-2]
- The dehydration-responsive element binding protein (DREB) family is important in regulating plant responses to abiotic stresses. DREB2C is one of the Arabidopsis class 2 DREBs and is induced by heat stress (HS). Here, we...
- Effect of nephrotoxicants and hepatotoxicants on gene expression profile in human peripheral blood mononuclear cells
[作者:Dadarkar, SS; Fonseca, LC; Thakkar, AD; Mishra, PB; Rangasamy, AK; Padigaru, M,期刊:Biochemical and Biophysical Research Communications, 页码:245-250 , 文章类型: Article,,卷期:2010年401-2]
- Studying peripheral blood transcriptome in the quest for translational markers of toxicity is considered to be an attractive offshoot in the field of toxicogenomics. Moreover, it is acknowledged that, xenobiotics which c...
- Crystallographic analysis reveals a unique conformation of the ADP-bound novel rice kinesin K16
[作者:Tanaka, K; Umeki, N; Mitsui, T; Fujimoto, Z; Maruta, S,期刊:Biochemical and Biophysical Research Communications, 页码:251-256 , 文章类型: Article,,卷期:2010年401-2]
- Biochemical studies revealed that the novel rice plant-specific kinesin K16 has several unique enzymatic characteristics as compared to conventional kinesins. The ADP-free form of K16 is very stable, whereas the ADP-free...
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