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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共11条记录   Poly(ADP-ribosyl)ation is implicated in the G0-G1 transition of resting cells [作者：Carbone, M; Rossi, MN; Cavaldesi, M; Notari, A; Amati, P; Maione, R,期刊：Oncogene, 页码：6083-6092 , 文章类型： Article，,卷期：2008年27-47] Poly(ADP-ribosyl)ation, catalysed by a family of poly (ADP-ribose) polymerases (PARPs), plays an important role in a large variety of physiological processes, including cell proliferation, but its role in cell cycle prog... Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta [作者：Brondello, JM; Pillaire, MJ; Rodriguez, C; Gourraud, PA; Selves, J; Cazaux, C; Piette, J,期刊：Oncogene, 页码：6093-6101 , 文章类型： Article，,卷期：2008年27-47] Cell cycle checkpoints and DNA repair act in concert to ensure DNA integrity during perturbation of normal replication or in response to genotoxic agents. Deficiencies in these protective mechanisms can lead to cellular ... The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice [作者：Hasselblatt, P; Gresh, L; Kudo, H; Guinea-Viniegra, J; Wagner, EF,期刊：Oncogene, 页码：6102-6109 , 文章类型： Article，,卷期：2008年27-47] Chronic inflammation is an important cancer risk factor but the molecular pathways linking inflammation and cancer are incompletely understood. The transcription factor c-Jun/AP-1 (activator protein 1) is involved in inf... Lipocalin 2 is required for BCR-ABL-induced tumorigenesis [作者：Leng, X; Lin, H; Ding, T; Wang, Y; Wu, Y; Klumpp, S; Sun, T; Zhou, Y; Monaco, P; Belmont, J; Aderem, A; Akira, S; Strong, R; Arlinghaus, R,期刊：Oncogene, 页码：6110-6119 , 文章类型： Article，,卷期：2008年27-47] Our previous studies indicate that reduction of lipocalin 2 (mouse 24p3) expression by either anti-sense or siRNA approaches strongly reduces the overgrowth of BCR-ABL + mouse myeloid 32D in marrow and spleen of NOD/SCID... ABINs inhibit EGF receptor-mediated NF-kappa B activation and growth of EGF receptor-overexpressing tumour cells [作者：Huang, L; Verstrepen, L; Heyninck, K; Wullaert, A; Revets, H; De Baetselier, P; Beyaert, R,期刊：Oncogene, 页码：6131-6140 , 文章类型： Article，,卷期：2008年27-47] The epidermal growth factor receptor (EGFR) is frequently overexpressed in various tumours of epidermal origin and is held responsible for tumourigenicity and tumour persistence. Increased nuclear factor (NF)-kappa B act... TSPY and its X-encoded homologue interact with cyclin B but exert contrasting functions on cyclin-dependent kinase 1 activities [作者：Li, Y; Lau, YFC,期刊：Oncogene, 页码：6141-6150 , 文章类型： Article，,卷期：2008年27-47] Testis-specific protein Y-encoded ( TSPY) is the putative gene for the gonadoblastoma locus on the Y chromosome (GBY). TSPY and an X-homologue, TSPX, harbor a conserved domain, designated as SET/NAP domain, but differ at... RASSF1A interacts with and activates the mitotic kinase Aurora-A [作者：Liu, L; Guo, C; Dammann, R; Tommasi, S; Pfeifer, GP,期刊：Oncogene, 页码：6175-6186 , 文章类型： Article，,卷期：2008年27-47] The RAS association domain family 1A (RASSF1A) gene is located at chromosome 3p21.3 within a specific area of common heterozygous and homozygous deletions. RASSF1A frequently undergoes promoter methylation-associated ina... A novel fusion 5 ' AFF3/3 ' BCL2 originated from a t(2;18)(q11.2;q21.33) translocation in follicular lymphoma [作者：Impera, L; Albano, F; Lo Cunsolo, C; Funes, S; Iuzzolino, P; Laveder, F; Panagopoulos, I; Rocchi, M; Storlazzi, CT,期刊：Oncogene, 页码：6187-6190 , 文章类型： Article，,卷期：2008年27-47] Follicular lymphoma is the second most frequent type of non-Hodgkin's lymphoma in adults. The basic molecular defect consists of the t(14;18)(q32;q21) translocation, juxtaposing the B-cell lymphoma protein 2 gene BCL2 to... HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion [作者：Korkaya, H; Paulson, A; Iovino, F; Wicha, MS,期刊：Oncogene, 页码：6120-6130 , 文章类型： Article，,卷期：2008年27-47] The cancer stem cell hypothesis proposes that cancers arise in stem/progenitor cells through disregulation of self-renewal pathways generating tumors, which are driven by a component of 'tumor-initiating cells' retaining... Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype [作者：Mazan-Mamczarz, K; Hagner, PR; Corl, S; Srikantan, S; Wood, WH; Becker, KG; Gorospe, M; Keene, JD; Levenson, AS; Gartenhaus, RB,期刊：Oncogene, 页码：6151-6163 , 文章类型： Article，,卷期：2008年27-47] In a breast tumor xenograft model, the MCT-1 oncogene increases the in vivo tumorgenicity of MCF7 cells by promoting angiogenesis and inhibiting apoptosis. Increases in the tumor microvascular density are accompanied by ... Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7 [作者：Ishikawa, Y; Onoyama, I; Nakayama, KI; Nakayama, K,期刊：Oncogene, 页码：6164-6174 , 文章类型： Article，,卷期：2008年27-47] The F-box protein Fbxw7 mediates the ubiquitylation and consequent degradation of proteins that regulate cell cycle progression, including cyclin E, c-Myc, c-Jun and Notch. Moreover, certain human cancer cell lines harbo...