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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共10条记录   New wirings in the survivin networks [作者：Altieri, DC,期刊：Oncogene, 页码：6276-6284 , 文章类型： Review，,卷期：2008年27-48] A little over 10 years after its discovery in 1997, the small inhibitor of apoptosis (IAP) protein, survivin, continues to generate intense interest and keen attention from disparate segments of basic and disease-related... Regulation of angiogenesis: apoptotic cues from the ECM [作者：Cheresh, DA; Stupack, DG,期刊：Oncogene, 页码：6285-6298 , 文章类型： Review，,卷期：2008年27-48] The extracellular matrix (ECM) acts both as a physical scaffold for cells and as a repository for growth factors. Moreover, ECM structure and physical-chemical properties convey precise information to cells that profound... Regulation of apoptosis by PML and the PML-NBs [作者：Bernardi, R; Papa, A; Pandolfi, PP,期刊：Oncogene, 页码：6299-6312 , 文章类型： Review，,卷期：2008年27-48] The promyelocytic leukemia protein (PML) is a tumor suppressor identified in acute PML and implicated in the pathogenesis of a variety of tumors. PML is essential for the proper assembly of a nuclear macromolecular struc... Caspases in apoptosis and beyond [作者：Li, J; Yuan, J,期刊：Oncogene, 页码：6194-6206 , 文章类型： Review，,卷期：2008年27-48] The demonstration of protein sequence and functional homology of the Caenorhabditis elegans programmed cell death gene product, CED-3, with human caspase-1 in 1993 triggered an explosion of research activities toward the... The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway [作者：Wang, S,期刊：Oncogene, 页码：6207-6215 , 文章类型： Review，,卷期：2008年27-48] Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and has been shown to induce apoptosis in cancer cells but not normal cells. TRAIL triggers apoptosis through bindi... FLIP and the death effector domain family [作者：Yu, JW; Shi, Y,期刊：Oncogene, 页码：6216-6227 , 文章类型： Review，,卷期：2008年27-48] Death effector domains (DEDs) are protein interaction modules found in a number of proteins known to regulate apoptosis from death receptors. The core DED family members that orchestrate programmed cell death from death ... NF-kappa B signaling, liver disease and hepatoprotective agents [作者：Sun, B; Karin, M,期刊：Oncogene, 页码：6228-6244 , 文章类型： Review，,卷期：2008年27-48] The NF-kappa B signaling pathway has particular relevance to several liver diseases including hepatitis (liver infection by Helicobacter, viral hepatitis induced by HBV and HCV), liver fibrosis and cirrhosis and hepatoce... JNK signaling in apoptosis [作者：Dhanasekaran, DN; Reddy, EP,期刊：Oncogene, 页码：6245-6251 , 文章类型： Review，,卷期：2008年27-48] Jun N-terminal kinases or JNKs play a critical role in death receptor-initiated extrinsic as well as mitochondrial intrinsic apoptotic pathways. JNKs activate apoptotic signaling by the upregulation of pro-apoptotic gene... IAP-targeted therapies for cancer [作者：LaCasse, EC; Mahoney, DJ; Cheung, HH; Plenchette, S; Baird, S; Korneluk, RG,期刊：Oncogene, 页码：6252-6275 , 文章类型： Review，,卷期：2008年27-48] DNA damage, chromosomal abnormalities, oncogene activation, viral infection, substrate detachment and hypoxia can all trigger apoptosis in normal cells. However, cancer cells acquire mutations that allow them to survive ... Foreword [作者：Reed, JC,期刊：Oncogene, 页码：6192-+ , 文章类型： Editorial Material，,卷期：2008年27-48]