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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共7条记录   A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation [作者：Chien, J; Narita, K; Rattan, R; Giri, S; Shridhar, R; Staub, J; Beleford, D; Lai, J; Roberts, LR; Molina, J; Kaufmann, SH; Prendergast, GC; Shridhar, V,期刊：Oncogene, 页码：7223-7234 , 文章类型： Article，,卷期：2008年27-58] The pathophysiological mechanisms that drive the development and progression of epithelial ovarian cancer remain obscure. Recently, we identified TCEAL7 as a transcriptional regulatory protein often downregulated in epit... Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling [作者：Guo, X; Waddell, DS; Wang, W; Wang, Z; Liberati, NT; Yong, S; Liu, X; Wang, XF,期刊：Oncogene, 页码：7235-7247 , 文章类型： Article，,卷期：2008年27-58] Transforming growth factor-beta (TGF-beta) elicits a variety of cellular activities primarily through a signaling cascade mediated by two key transcription factors, Smad2 and Smad3. Numerous regulatory mechanisms exist t... Loss of Hus1 sensitizes cells to etoposide-induced apoptosis by regulating BH3-only proteins [作者：Meyerkord, CL; Takahashi, Y; Araya, R; Takada, N; Weiss, RS; Wang, HG,期刊：Oncogene, 页码：7248-7259 , 文章类型： Article，,卷期：2008年27-58] The Rad9-Rad1-Hus1 (9-1-1) cell cycle checkpoint complex plays a key role in the DNA damage response. Cells with a defective 9-1-1 complex have been shown to be sensitive to apoptosis induced by certain types of genotoxi... Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor [作者：Wykosky, J; Palma, E; Gibo, DM; Ringler, S; Turner, CP; Debinski, W,期刊：Oncogene, 页码：7260-7273 , 文章类型： Article，,卷期：2008年27-58] The ephrinA1 ligand exerts antioncogenic effects in tumor cells through activation and downregulation of the EphA2 receptor and has been described as a membrane-anchored protein requiring clustering for function. However... Repression of E-cadherin by the polycomb group protein EZH2 in cancer [作者：Cao, Q; Yu, J; Dhanasekaran, SM; Kim, JH; Mani, RS; Tomlins, SA; Mehra, R; Laxman, B; Cao, X; Yu, J; Kleer, CG; Varambally, S; Chinnaiyan, AM,期刊：Oncogene, 页码：7274-7284 , 文章类型： Article，,卷期：2008年27-58] Enhancer of zeste homolog 2 (EZH2) is a critical component of the polycomb-repressive complex 2 (PRC2), which is involved in gene silencing and histone H3 lysine 27 methylation. EZH2 has a master regulatory function in c... TTK/Mps1 controls nuclear targeting of c-Abl by 14-3-3-coupled phosphorylation in response to oxidative stress [作者：Nihira, K; Taira, N; Miki, Y; Yoshida, K,期刊：Oncogene, 页码：7285-7295 , 文章类型： Article，,卷期：2008年27-58] Upon exposure to genotoxic stress, the c-Abl tyrosine kinase is released from cytoplasmic 14-3-3 proteins and then is targeted to the nucleus. Phosphorylation of Thr735 in c-Abl is critical for binding to 14-3-3; however... Implication of human N-alpha-acetyltransferase 5 in cellular proliferation and carcinogenesis [作者：Ametzazurra, A; Larrea, E; Civeira, MP; Prieto, J; Aldabe, R,期刊：Oncogene, 页码：7296-7306 , 文章类型： Article，,卷期：2008年27-58] The N-alpha-acetyltransferase NatB, composed in Saccharomyces cerevisiae by the Nat3p and Mdm20p subunits, is an important factor for yeast growth and resistance to several stress agents. However, the expression and func...