- Peroxynitrite scavenging by ferryl sperm whale myoglobin and human hemoglobin
[作者:Ascenzi, P; De Marinis, E; di Masi, A; Ciaccio, C; Coletta, M,期刊:Biochemical and Biophysical Research Communications, 页码:27-31 , 文章类型: Article,,卷期:2009年390-1]
- Globins protect from the oxidative and nitrosative cell damage. Here, kinetics of peroxynitrite scavenging by ferryl sperm whale myoglobin (Mb-Fe(IV)=O) and human hemoglobin (Hb-Fe(IV)=O), between pH 5.8 and 8.3 at 20.0 ...
- DNA polymerase mu interacts with a meiosis-specific RecA homolog Lim15 during meiosis in Coprinus cinereus
[作者:Yanai, T; Sakamoto, A; Iwabata, K; Koshiyama, A; Sugawara, H; Nara, T; Takakusagi, Y; Sakaguchi, K,期刊:Biochemical and Biophysical Research Communications, 页码:32-37 , 文章类型: Article,,卷期:2009年390-1]
- Meiosis is a fundamental process in eukaryotes. Homologous chromosomes are paired and recombined during meiotic prophase 1, which results in variation among the gametes. However, the mechanism of recombination between th...
- Mitochondrial apoptosis is amplified through gap junctions
[作者:Peixoto, PM; Ryu, SY; Pruzansky, DP; Kuriakose, M; Gilmore, A; Kinnally, KW,期刊:Biochemical and Biophysical Research Communications, 页码:38-43 , 文章类型: Article,,卷期:2009年390-1]
The death of one cell can precipitate the death of nearby cells in a process referred to as the bystander effect. We investigated whether mitochondrial apoptosis generated a bystander effect and, if so, by which pathw...
- Escape mechanisms from antibody therapy to lymphoma cells: Downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation
[作者:Sugimoto, T; Tomita, A; Hiraga, J; Shimada, K; Kiyoi, H; Kinoshita, T; Naoe, T,期刊:Biochemical and Biophysical Research Communications, 页码:48-53 , 文章类型: Article,,卷期:2009年390-1]
- Although rituximab is a critical monoclonal antibody therapy for CD20-positive B-cell lymphomas, rituximab resistance showing a CD20-negative phenotypic change has been a considerable clinical problem. Here we demonstrat...
- Usual and unusual biochemical properties of ADF/cofilin-like protein Adf73p in ciliate Tetrahymena thermophila
[作者:Shiozaki, N; Nakano, K; Takaine, M; Abe, H; Numata, O,期刊:Biochemical and Biophysical Research Communications, 页码:54-59 , 文章类型: Article,,卷期:2009年390-1]
- Actin-depolymerizing factor (ADF)/cofilin is a well-conserved actin-modulating protein, which induces reorganization of the actin cytoskeleton by severing and depolymerizing F-actin. ADF/cofilin also binds to G-actin and...
- Induction of oncogene addiction shift to NF-kappa B by camptothecin in solid tumor cells
[作者:Togano, T; Sasaki, M; Watanabe, M; Nakashima, M; Tsuruo, T; Umezawa, K; Higashihara, M; Watanabe, T; Horie, R,期刊:Biochemical and Biophysical Research Communications, 页码:60-64 , 文章类型: Article,,卷期:2009年390-1]
- The biological basis of the resistance of solid tumor cells to chemotherapy is not well understood. While addressing this problem, we found that gastric cancer cell line St-4/CPIT, lung cancer cell line A549/CPT, and col...
- Wnt modulators, SFRP-1, and SFRP-2 are expressed in osteoblasts and differentially regulate hematopoietic stem cells
[作者:Nakajima, H; Ito, M; Morikawa, Y; Komori, T; Fukuchi, Y; Shibata, F; Okamoto, S; Kitamura, T,期刊:Biochemical and Biophysical Research Communications, 页码:65-70 , 文章类型: Article,,卷期:2009年390-1]
- Writ signaling has been implicated in the self-renewal of hematopoietic stem cells (HSCs). Secreted frizzled-related proteins (SFRPs) are a family of soluble proteins containing a region homologous to a receptor for Writ...
- Silibinin inhibits expression of HIF-1 alpha through suppression of protein translation in prostate cancer cells
[作者:Jung, HJ; Park, JW; Lee, JS; Lee, SR; Jang, BC; Suh, SI; Suh, MH; Baek, WK,期刊:Biochemical and Biophysical Research Communications, 页码:71-76 , 文章类型: Article,,卷期:2009年390-1]
- Silibinin is a polyphenolic flavonoid isolated from the milk thistle (Silybum marianum) and is reported to exhibit anticancer properties. Recently, it has been reported that silibinin inhibits hypoxia-inducible factor-1 ...
- Metabotropic glutamate receptor 4 interacts with microtubule-associated protein 1B
[作者:Moritz, A; Scheschonka, A; Beckhaus, T; Karas, M; Betz, H,期刊:Biochemical and Biophysical Research Communications, 页码:82-86 , 文章类型: Article,,卷期:2009年390-1]
- The metabotropic glutamate receptor 4 (mGluR4) is a G-protein-coupled receptor that mediates inhibition of neurotransmitter release. Here, we used a proteomic approach to identify novel interaction partners of mGluR4 and...
- Protein kinase A-dependent phosphorylation of ryanodine receptors increases Ca2+ leak in mouse heart
[作者:Morimoto, S; O-Uchi, J; Kawai, M; Hoshina, T; Kusakari, Y; Komukai, K; Sasaki, H; Hongo, K; Kurihara, S,期刊:Biochemical and Biophysical Research Communications, 页码:87-92 , 文章类型: Article,,卷期:2009年390-1]
- In heart failure, chronic catecholaminergic stimulation increases diastolic Ca2+ leak from ryanodine receptors (RyRs) of sarcoplasmic reticulum (SR), possibly due to the phosphorylation of RyRs through the activation of ...
- An advanced blue-white screening method for construction of shRNA expression vectors
[作者:Yang, J; Xu, J; Zhong, X; Zhang, Y; Wu, Q; Li, WJ; Zhang, X; Zhen, P; Yang, XS; Chen, L; Wang, YP; Zhu, DW; Zhai, C; Ma, LX,期刊:Biochemical and Biophysical Research Communications, 页码:97-102 , 文章类型: Article,,卷期:2009年390-1]
- Short hairpin RNA (shRNA) encoded within an expression vector is an effective tool for exploration of gene function in mammalian cells. Many of the current methods for constructing shRNA expression vectors require cumber...
- Demethylallosamidin, a chitinase inhibitor, suppresses airway inflammation and hyperresponsiveness
[作者:Matsumoto, T; Inoue, H; Sato, Y; Kita, Y; Nakano, T; Noda, N; Eguchi-Tsuda, M; Moriwaki, A; Kan-o, K; Matsumoto, K; Shimizu, T; Nagasawa, H; Sakuda, S; Nakanishi, Y,期刊:Biochemical and Biophysical Research Communications, 页码:103-108 , 文章类型: Article,,卷期:2009年390-1]
- Acidic mammalian chitinase is upregulated in response to allergen exposure in the lung. We investigated the effects of chitinase inhibitors, allosamidin (Allo) and demethylallosamidin (Dma), on asthmatic responses. Mice ...
- Sorting nexin 8 regulates endosome-to-Golgi transport
[作者:Dyve, AB; Bergan, J; Utskarpen, A; Sandvig, K,期刊:Biochemical and Biophysical Research Communications, 页码:109-114 , 文章类型: Article,,卷期:2009年390-1]
- Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family, whose members are involved in endocytosis and endosomal sorting and signaling. The function of SNX8 has so far been unknown. Here, we have investigated ...
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