This article describes the examination of several synthetic methodologies that have been developed in our laboratories, by application to the construction of a variety of natural product targets.
Inverse opal structured tungsten trioxide (WO3) films with mesoporous morphology were prepared using self-assembled polystyrene (PS) colloid as an organic template and by addition of polyethyleneglycol (PEG) to a precurs...
We report a method for detecting microRNAs encapsulated in exosomes using a microelectrode array in semiconductor-based potentiometry after RT-PCR. The inherent miniaturization of the electrical biosensor meets requireme...
An Rh4Ni alloy nanocatalyst exhibits highly-efficient performance in dehydrogenation of aqueous hydrazine borane. The hydrogen selectivity reaches almost 100%. More interestingly, catalyzed by the Rh4Ni nanocatalyst, the...
The characterisation of porous crystalline solids often relies on single crystal X-ray diffraction, which does not give direct information about the surface of the material. Here, crystals of a porous organic cage, CC3-R...
A novel and efficient palladium-catalysed direct di-heteroarylation of 1,2-dichloroperfluorocyclopentene with a variety of heteroarenes is reported, giving rise to 1,2-di(heteroaryl)ylperfluorocyclopentene photochromic c...
Highly fluorescent core-shell hybrid nanoparticles were readily fabricated from the soft template of a unimolecular star conjugated polymer (HCP-star-PDMAEMA). Since the hyperbranched conjugated polymer (HCP) core was is...
Yeast displaying glucose oxidase on their surface were encapsulated in a graphene oxide hydrogel. The ability of the modified yeast to reduce graphene oxide by glucose assimilation while maintaining viability was tested ...
A relay catalysis protocol for the functionalization of alpha-amino acids and dipeptides using a combination of visible-light photoredox and Lewis acid catalysis has been developed.
The frustrated Lewis pair, B(C6F5)(3)/Ph2PC6F5, acts as an efficient catalyst for the hydrogenation of the polycyclic hydrocarbons including anthracene derivatives, tetracene and tetraphene, at 80 degrees C and 100 atm H...
A novel multicomponent strategy for the efficient synthesis of tricyclic pyrrolo[1,2-a]quinolines has been described. The bond-forming efficiency, accessibility and generality of this synthesis make it highly attractive ...
A range of nucleoside phosphoramidites incorporating small amino substituents have been readily synthesised using ionic liquid stabilised phosphorodiamidites coupled with mechanochemistry.
The addition of a magnetic composite membrane to a traditional nickel electrocatalyst was employed to increase the methanol and n-butanol electrocatalysis in alkaline media.
Two peptidomimetic macrocycles, regioisomeric in terms of the position of triazole/amide, have been synthesized. Both undergo self-assembly in a parallel manner but in solvents of opposite polarity, ascribed to (beta, be...
The synthesis of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)-methylidene]piperidine-2,6-dione 4 from N-benzylglutarimide was achieved in three steps. The asymmetric hydrogenation of 4 gave either the product of partial redu...
Nitric oxide binds reversibly to the Fe(III) complex of a well-developed tetra-amido macrocyclic ligand. Reaction with NO results in formation of a species consistent with an S = 1 {Fe-NO}(6) ground state as characterize...