- 2-methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A
[作者:Wang, YL; Chen, Y; Xu, W; Lee, DYW; Ma, ZZ; Rawls, SM; Cowan, A; Liu-Chen, LY,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:1073-1083 , 文章类型: Article,,卷期:2008年324-3]
Salvinorin ( Sal) A is a naturally occurring, selective kappa opioid receptor (KOPR) agonist with a short duration of action in vivo. Pharmacological properties of a C( 2) derivative, 2-methoxy-methyl (MOM)-Sal B, wer...
- Inhibitor binding in the human renal low- and high-affinity Na+/glucose cotransporters
[作者:Pajor, AM; Randolph, KM; Kerner, SA; Smith, CD,期刊:Journal of Pharmacology and Experimental Therapeutics, 页码:985-991 , 文章类型: Article,,卷期:2008年324-3]
The kidney contains two Na+/glucose cotransporters, called SGLT2 and SGLT1, arranged in series along the length of the proximal tubule. The low-affinity transporter, SGLT2, is responsible for the reabsorption of most ...
|