- Synthesis, Inhibitory Activity of Cholinesterases, and Neuroprotective Profile of Novel 1,8-Naphthyridine Derivatives
[作者:DE LOS RIOS CRISTOBAL; EGEA JAVIER; MARCOCONTELLES JOSE; LEON RAFAEL; SAMADI ABDELOUAHID; IRIEPA ISABEL; MORALEDA IGNACIO; GALVEZ ENRIQUE; GARCIA ANTONIO G; LOPEZ MANUELA G; VILLARROYA MERCEDES; ROMERO ALEJANDRO,期刊:Journal of Medicinal Chemistry, 页码:5129-5143 , 文章类型: Article,,卷期:2010年53-14]
- 1,8-Naphthyridine derivatives related to 17 (ITH4012), a neuroprotective compound reported by our research group, have been synthesized. In general, they have shown better inhibition of acetylcholinesterase (AChE) and bu...
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