- Specific targeting of the vasculature of gastric cancer by a new tumor-homing peptide CGNSNPKSC
[作者:Hui, XL; Han, Y; Liang, SH; Liu, ZG; Liu, JT; Hong, L; Zhao, L; He, L; Cao, SS; Chen, B; Yan, K; Jin, B; Chai, N; Wang, J; Wu, KC; Fan, DM,期刊:Journal of controlled release, 页码:86-93 , 文章类型: Article,,卷期:2008年131-2]
- Discovery of tumor vascular specific molecules to improve the targeting ability of cytotoxic agents plays an important role in antiangiogenesis. We had found a peptide GX1 (CGNSNPKSC) binding to vasculature endothelial c...
- A transcutaneous vaccination system using a hydrogel patch for viral and bacterial infection
[作者:Ishii, Y; Nakae, T; SakaMoto, F; Matsuo, K; Matsuo, K; Quan, YS; Kamiyama, F; Fujita, T; Yamamoto, A; Nakagawa, S; Okada, N,期刊:Journal of controlled release, 页码:113-120 , 文章类型: Article,,卷期:2008年131-2]
- One of the most important anthropic missions is preventing the global spread of infectious diseases. Vaccination is the only available preventive treatment for infectious diseases, but the availability of vaccines in dev...
- Treatment of osteomyelitis in rats by injection of degradable polymer releasing gentamicin
[作者:Brin, YS; Golenser, J; Mizrahi, B; Maoz, G; Domb, AJ; Peddada, S; Tuvia, S; Nyska, A; Nyska, M,期刊:Journal of controlled release, 页码:121-127 , 文章类型: Article,,卷期:2008年131-2]
- We evaluated the potential of an injectable degradable polymer-poly(sebacic-co-ricinoleic-ester-anhydride) containing gentamicin for the treatment of osteomyelitis. Osteomyelitis of both tibiae was induced in 13 female F...
- Loading dependent swelling and release properties of novel biodegradable, elastic and environmental stimuli-sensitive polyurethanes
[作者:Zhang, CH; Zhao, KJ; Hu, TY; Cui, XF; Brown, N; Boland, T,期刊:Journal of controlled release, 页码:128-136 , 文章类型: Article,,卷期:2008年131-2]
- A novel degradable, elastic, anionic, and linear polyurethane was synthesized from hexamethylene diisocyanate, polycaprolactone diol, and a bicine chain extender. The chemical structure, mechanical properties, degradatio...
- Supramolecular control of polyplex dissociation and cell transfection: Efficacy of amino groups and threading cyclodextrins in biocleavable polyrotaxanes
[作者:Yamashita, A; Kanda, D; Katoono, R; Yui, N; Ooya, T; Maruyama, A; Akita, H; Kogure, K; Harashima, H,期刊:Journal of controlled release, 页码:137-144 , 文章类型: Article,,卷期:2008年131-2]
- A novel strategy for gene delivery using biocleavable polyrotaxanes, in which dimethylaminoethyl-modified alpha-cyclodextrins (DMAE-alpha-CDs) are threaded onto a poly(ethylene glycol) (PEG) chain capped with benzyloxyca...
- Glycosaminoglycan-resistant and pH-sensitive lipid-coated DNA complexes produced by detergent removal method
[作者:Lehtinen, J; Hyvonen, Z; Subrizi, A; Bunjes, H; Urtti, A,期刊:Journal of controlled release, 页码:145-149 , 文章类型: Article,,卷期:2008年131-2]
- Cationic polymers are efficient gene delivery vectors in in vitro conditions, but these carriers can fail in vivo due to interactions with extracellular polyanions, i.e. glycosaminoglycans (GAG). The aim of this study wa...
- Galactosylated poly(ethylene glycol)-chitosan-graft-polyethylenimine as a gene carrier for hepatocyte-targeting
[作者:Jiang, HL; Kwon, JT; Kim, EM; Kim, YK; Arote, R; Jere, D; Jeong, HJ; Jang, MK; Nah, JW; Xu, CX; Park, IK; Cho, MH; Cho, CS,期刊:Journal of controlled release, 页码:150-157 , 文章类型: Article,,卷期:2008年131-2]
- Chitosan and chitosan derivatives have been proposed as alternative and biocompatible cationic polymers for non-viral gene delivery. However. the low transfection efficiency and low specificity of chitosan is an aspect o...
|