- Drosophila expresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties
[作者:Reynolds, B; Roversi, P; Laynes, R; Kazi, S; Boyd, CAR; Goberdhan, DCI,期刊:Biochemical Journal, 页码:363-372 , 文章类型: Article,,卷期:2009年420-Part 3]
- Mammalian CD98 heterodimeric amino acid transporters consist of a promiscuous single-pass transmembrane glycoprotein, CD98hc (CD98 heavy chain), and one of six multipass transmembrane proteins or 'light chains'. The hete...
- Triton X-100 promotes a cholesterol-dependent condensation of the plasma membrane
[作者:Ingelmo-Torres, M; Gaus, K; Herms, A; Gonzalez-Moreno, E; Kassan, A; Bosch, M; Grewal, T; Tebar, F; Enrich, C; Pol, A,期刊:Biochemical Journal, 页码:373-381 , 文章类型: Article,,卷期:2009年420-Part 3]
- The molecular components of membrane rafts are frequently defined by their biochemical partitioning into detergent-resistant membranes. In the present Study, we used a combination of epifluorescence and two-photon micros...
- Haemolytic anaemia and alterations in hepatic iron metabolism in aged mice lacking Cu,Zn-superoxide dismutase
[作者:Starzynski, RR; Canonne-Hergaux, F; Willemetz, A; Gralak, MA; Wolinski, J; Stys, A; Olszak, J; Lipinski, P,期刊:Biochemical Journal, 页码:383-390 , 文章类型: Article,,卷期:2009年420-Part 3]
- The continuous recycling of haem iron following phagocytosis and catabolism of senescent and damaged red blood cells by macrophages is a crucial process in the maintenance of systemic iron homoeostosis. However, little i...
- Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity
[作者:Riedle, S; Kiefel, H; Gast, D; Bondong, S; Wolterink, S; Gutwein, P; Altevogt, P,期刊:Biochemical Journal, 页码:391-402 , 文章类型: Article,,卷期:2009年420-Part 3]
- L1-CAM (L1 cell-adhesion molecule), or more simply L1, plays an important role ill the progression of human carcinoma. Overexpression promotes tumour-cell invasion and motility, growth in nude mice and tumour metastasis....
- KLF4 positively regulates human ghrelin expression
[作者:Lee, HJ; Kang, YM; Moon, CS; Joe, MK; Lim, JH; Suh, YH; Song, J; Jung, MH,期刊:Biochemical Journal, 页码:403-411 , 文章类型: Article,,卷期:2009年420-Part 3]
- Ghrelin, an endogenours ligand of the GH (growth hormone) secretagogue receptor, influences many metabolic processes including GH secretion, food intake, energy balance, insulin secretion and adipogenesis. Although ghrel...
- N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan
[作者:Aoyama, E; Hattori, T; Hoshijima, M; Araki, D; Nishida, T; Kubota, S; Takigawa, M,期刊:Biochemical Journal, 页码:413-420 , 文章类型: Article,,卷期:2009年420-Part 3]
- CCN2/CTGF (CCN family 2/connective tissue growth factor) is a multi-cellular protein with a broad range of activities. It modulates many cellular functions, including proliferation, migration, adhesion and extracellular ...
- RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II
[作者:Tang, W; You, WH; Shi, F; Qi, TY; Wang, L; Djouder, ZN; Liu, WG; Zeng, XL,期刊:Biochemical Journal, 页码:421-428 , 文章类型: Article,,卷期:2009年420-Part 3]
- Actin, the major component of the cytoplasmic skeleton, has been shown to exist in the nucleus. Nuclear actin functions in several steps of the transcription process, including chromatin remodelling and transcription ini...
- Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids
[作者:Akkaoui, M; Cohen, I; Esnous, C; Lenoir, V; Sournac, M; Girard, J; Prip-Buus, C,期刊:Biochemical Journal, 页码:429-438 , 文章类型: Article,,卷期:2009年420-Part 3]
- Liver mitochondrial beta-oxidation of LCFAs (long-chain fatty acids) is tightly regulated through inhibition of CPT1A (carnitine palmitoyltransferase 1A) by malonyl-CoA, all intermediate of lipogenesis stimulated by gluc...
- Role of nuclear-encoded subunit Vb in the assembly and stability of cytochrome c oxidase complex: implications in mitochondrial dysfunction and ROS production
[作者:Galati, D; Srinivasan, S; Raza, H; Prabu, SK; Hardy, M; Chandran, K; Lopez, M; Kalyanaraman, B; Avadhani, NG,期刊:Biochemical Journal, 页码:439-449 , 文章类型: Article,,卷期:2009年420-Part 3]
- CcO (cytochrome c oxidase) is a multisubunit bigenomic protein complex which catalyses the last step of the mitochondrial electron transport chain. The nuclear-encoded subunits are thought to have roles either in regulat...
- IscA/SufA paralogues are required for the [4Fe-4S] cluster assembly in enzymes of multiple physiological pathways in Escherichia coli under aerobic growth conditions
[作者:Tan, GQ; Lu, JX; Bitoun, JP; Huang, H; Ding, HG,期刊:Biochemical Journal, 页码:463-472 , 文章类型: Article,,卷期:2009年420-Part 3]
- IscA/SufA paralogues are the members of the iron-sulfur cluster-assembly machinery in Escherichia coli. Whereas deletion of either IscA or SufA has only a mild effect on cell growth, deletion of both IscA and SufA result...
- Human caspase 7 is positively controlled by SREBP-1 and SREBP-2
[作者:Gibot, L; Follet, J; Metges, JP; Auvray, P; Simon, B; Corcos, L; Le Jossic-Corcos, C,期刊:Biochemical Journal, 页码:473-483 , 文章类型: Article,,卷期:2009年420-Part 3]
- Statins are lipid-lowering drugs that may help limit cancer occurrence in humans. They drive blockage of the mevalonate pathway, trigger cancer cell apoptosis in vitro and reduce tumour incidence in animals. We have show...
- Thermodynamic characterization of the redox centres in a representative domain of a novel c-type multihaem cytochrome
[作者:Morgado, L; Fernandes, AR; Londer, YY; Pokkuluri, PR; Schiffer, M; Salgueiro, CA,期刊:Biochemical Journal, 页码:485-492 , 文章类型: Article,,卷期:2009年420-Part 3]
- Multihaem cytochromes that could form protein "nanowires" were identified in the Geobacter sulfurreducens genome, and represent a new type of mulithaem cytochrome. The sequences of these proteins, two with 12 haems (GSU ...
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